ChemicalBook >> CAS DataBase List >>4-chloro-7-Methoxyquinoline-6-carboxaMide

4-chloro-7-Methoxyquinoline-6-carboxaMide

4-chloro-7-Methoxyquinoline-6-carboxaMide structure

CAS No.: 417721-36-9

Chemical Name:: 4-chloro-7-Methoxyquinoline-6-carboxaMide

Synonyms: lenvaint-E;synthesis-024;synthesis-1-014;ine-6-carboxamide;oro-7-methoxyquinoL;Lenvatinib Impurity b;Lenvatinib Impurity 50;Lenvatinib Impurity LFS-B;4-chloro-7-Methoxy-6-QuinolinecarboxaMide;4-chloro-7-Methoxyquinoline-6-carboxaMide

CBNumber:: CB12596687

Molecular Formula:: C11H9ClN2O2

Molecular Weight:: 236.65

MDL Number:: MFCD13192256

MOL File:: 417721-36-9.mol

Last updated:2024-04-16 11:06:30

Request For Quotation

4-chloro-7-Methoxyquinoline-6-carboxaMide Properties

Melting point	>205°C (dec.)
Boiling point	426.7±45.0 °C(Predicted)
Density	1.380±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	15.28±0.30(Predicted)
form	Solid
color	Off-White to Light Beige
InChI	InChI=1S/C11H9ClN2O2/c1-16-10-5-9-6(4-7(10)11(13)15)8(12)2-3-14-9/h2-5H,1H3,(H2,13,15)
InChIKey	ZBTVNIDMGKZSGC-UHFFFAOYSA-N
SMILES	N1C2C(=CC(C(N)=O)=C(OC)C=2)C(Cl)=CC=1
CAS DataBase Reference	417721-36-9

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933499090

4-chloro-7-Methoxyquinoline-6-carboxaMide price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C369515	4-Chloro-7-methoxy-6-quinolinecarboxamide	417721-36-9	1g	$85	2021-12-16	Buy
Biosynth Carbosynth	FC158634	4-Chloro-7-methoxyquinoline-6-carboxamide	417721-36-9	2g	$120	2021-12-16	Buy
Biosynth Carbosynth	FC158634	4-Chloro-7-methoxyquinoline-6-carboxamide	417721-36-9	500mg	$45	2021-12-16	Buy
Apolloscientific	OR53151	4-Chloro-7-methoxyquinoline-6-carboxamide 97%	417721-36-9	5g	$145	2021-12-16	Buy
SynQuest Laboratories	4H48-5-C6	4-Chloro-7-methoxyquinoline-6-carboxamide 97%	417721-36-9	5G	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
C369515	1g	$85	Buy
FC158634	2g	$120	Buy
FC158634	500mg	$45	Buy
OR53151	5g	$145	Buy
4H48-5-C6	5G	$160	Buy

4-chloro-7-Methoxyquinoline-6-carboxaMide Chemical Properties,Uses,Production

Description

4-chloro-7-Methoxyquinoline-6-carboxaMide is a pharmaceutical intermediate compound used in the preparation of Lenvatinib, an oral multi-receptor tyrosine kinase inhibitor approved by the FDA for the treatment of radioiodine-refractory differentiated thyroid cancer (DTC), unresectable (DTC), unresectable hepatocellular carcinoma (HCC), and advanced renal cell carcinoma (RCC).

Chemical Properties

light yellow powder

Uses

Pharmaceutical Intermediates. 4-chloro-7-Methoxyquinoline-6-carboxaMide is used as an intermediate for synthesizing Lenvatinibis.

4-chloro-7-Methoxyquinoline-6-carboxaMide synthesis

Synthesis of 4-chloro-7-Methoxyquinoline-6-carboxaMide from 4-chloro-7-Methoxyquinoline-6-carbonitrile

4-chloro-7-Methoxyquinoline-6-carboxaMide Preparation Products And Raw materials

Raw materials

Methyl 4-chloro-7-Methoxyquinoline-6-carboxylate 4-chloro-7-Methoxyquinoline-6-carbonitrile

Preparation Products

4-chloro-7-Methoxyquinoline-6-carboxaMide Suppliers

Global( 339)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
SyncoZymes (Shanghai) Co., Ltd.,	+86-021-68187180-811 +86-13681683526	lchen@syncozymes.com	China	188	58
Beijing Mediking Biopharm Co., Ltd	+undefined15901403431	sales01@mediking.cn	China	150	58
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Jinan Million Pharmaceutical Co., Ltd	+86-531-68659554 +8613031714605	info@millionpharm.com	China	153	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55

Supplier	Advantage
SyncoZymes (Shanghai) Co., Ltd.,	58
Beijing Mediking Biopharm Co., Ltd	58
Hebei Guanlang Biotechnology Co,.LTD	58
Henan Bao Enluo International TradeCo.，LTD	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Jinan Million Pharmaceutical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 4-chloro-7-Methoxyquinoline-6-carboxaMide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	4-chloro-7-Methoxyquinoline-6-carboxaMide 417721-36-9	US $100.00-95.00 / kg	1kg	99.99%	100Tons	Hebei Dangtong Import and export Co LTD
2024-04-19	4-chloro-7-Methoxyquinoline-6-carboxaMide 417721-36-9	US $1.00-0.50 / kg	1kg	99%	200kg	Jinan Million Pharmaceutical Co., Ltd
2024-01-02	4-chloro-7-Methoxyquinoline-6-carboxaMide 417721-36-9	US $90.00-900.00 / kg	10kg	0.99	20tons	Zibo Hangyu Biotechnology Development Co., Ltd

4-chloro-7-Methoxyquinoline-6-carboxaMide
417721-36-9
US $100.00-95.00 / kg
99.99%
Hebei Dangtong Import and export Co LTD

4-chloro-7-Methoxyquinoline-6-carboxaMide
417721-36-9
US $1.00-0.50 / kg
99%
Jinan Million Pharmaceutical Co., Ltd

4-chloro-7-Methoxyquinoline-6-carboxaMide
417721-36-9
US $90.00-900.00 / kg
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

4-chloro-7-Methoxyquinoline-6-carboxaMide Spectrum

4-chloro-7-Methoxyquinoline-6-carboxaMide(417721-36-9)¹HNMR

417721-36-9(4-chloro-7-Methoxyquinoline-6-carboxaMide)Related Search:

7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxaMide 1-(2-chloro-4-hydroxyphenyl)-3-cyclopropylurea 7-methoxy-4-chloro-quinoline-6-carbonyl chloride Cyhalothrin Clioquinol

Lansoprazole L-Glutamine, phenylmethyl ester 2-AMINOMETHYLPYRIMIDINE HYDROCHLORIDE Lenvatinib Impurity d Lenvatinib Impurity 12

Lenvatinib Impurity g synthesis-020 synthesis-022 4-Amino-3-chlorophenol hydrochloride lenvatinib Mesylate

Methyl 7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylate Methyl 4-chloro-7-Methoxyquinoline-6-carboxylate 4-Amino-3-chlorophenol

1of4

6-QuinolinecarboxaMide, 4-chloro-7-Methoxy- 4-chloro-7-Methoxyquinoline-6-carboxaMide 4-chloro-7-Methoxy-6-QuinolinecarboxaMide Lenvatinib Impurity b 4-Chloro-7-methoxy-quinoline-6-carboxylic acid amide 4-Chloro-7-methoxyquinazoline-6-carboxamide Lenvatinib Impurity LFS-B synthesis-024 lenvaint-E ine-6-carboxamide oro-7-methoxyquinoL synthesis-1-014 Lenvatinib Impurity 50 417721-36-9 477721-36-9 Intermediate 417721-36-9