ChemicalBook >> CAS DataBase List >>(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL

CAS No.
3947-65-7
Chemical Name:
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
Synonyms
NEAMINE;Neamine CRS;U-5214;neamin;C01441;Negamicin;neomycina;dekamycinv;nebramycinx;Framycetin EP Impurity A
CBNumber:
CB1262623
Molecular Formula:
C12H26N4O6
Molecular Weight:
322.36
MDL Number:
MFCD00023857
MOL File:
3947-65-7.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Properties

Melting point 225.5°C (rough estimate)
Boiling point 460.98°C (rough estimate)
alpha D25+112.8° (c = 1)
Density 1.1885 (rough estimate)
refractive index 1.6120 (estimate)
storage temp. Hygroscopic, Refrigerator, Under inert atmosphere
solubility Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)
pka 13.24±0.70(Predicted)
color White to Pale Yellow
Stability Hygroscopic
FDA UNII 5981U00LY0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N0300000 Neamine European Pharmacopoeia (EP) Reference Standard 3947-65-7 n0300000 $220 2024-03-01 Buy
Usbiological 297624 Neamine 3947-65-7 5mg $333 2021-12-16 Buy
TRC N386010 Neamine 3947-65-7 100mg $435 2021-12-16 Buy
Biosynth Carbosynth ON32335 Neamine 3947-65-7 50mg $350 2021-12-16 Buy
AK Scientific A779 Neamine 3947-65-7 5mg $234 2021-12-16 Buy
Product number Packaging Price Buy
N0300000 n0300000 $220 Buy
297624 5mg $333 Buy
N386010 100mg $435 Buy
ON32335 50mg $350 Buy
A779 5mg $234 Buy

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Chemical Properties,Uses,Production

Uses

Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents.

Definition

ChEBI: 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group.

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL U-5214 2-deoxy-4-o-(2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl)-d-streptamin (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL dekamycinv neamin nebramycinx neomycina 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine Negamicin C01441 Neomycin A sulfate (Neamine) 5-amino-2-(aminomethyl)-6-(4,6-diamino-2,3-dihydroxycyclohexyl)oxyoxane-3,4-diol 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine (neamine or neomycin A-LP) Neomycin sulfate impurity A Neomycin Sulfate Impurity 1(Neomycin Sulfate EP Impurity A) Neomycin Sulfate EP Impurity A (Neamine) Neomycin Sulfate EP Impurity A D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)- Framycetin EP Impurity A Tobramycin Impurity 3 (Tobramycin EP Impurity C) (Neamine) (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol (1R,3S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL Framycetin Impurity 1 (Framycetin EP Impurity A) Framycetin sulfate EP Impurity A Neamine (N0300000)Q: What is Neamine (N0300000) Q: What is the CAS Number of Neamine (N0300000) Q: What are the applications of Neamine (N0300000) Neomycin Sulfate EP Impurity A (Neamine)Q: What is Neomycin Sulfate EP Impurity A (Neamine) Q: What is the CAS Number of Neomycin Sulfate EP Impurity A (Neamine) Q: What is the storage condition of Neomycin Sulfate EP Impurity A (Neamine) Q: What are the applications of Neomycin Sulfate EP Impurity A (Neamine) NEAMINE Neamine CRS Neamine (synonym: Neomycin Sulfate EP Impurity A) 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine (neamine or neomycin A-LP) 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine (neamine) Neomycin Sulfate EP Impurity A(Tobramycin EP Impurity C) Neomycin A Sulfate (Neamine), EvoPure 3947-65-7 C12H26N4O6 Intermediates