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Rolapitant

CAS No.
552292-08-7
Chemical Name:
Rolapitant
Synonyms
Roltant;SCH619734;Rolapitant;Rolapitant-d4;Rolapitant HCl;brand name: Varubi;Rolapitant USP/EP/BP;SCH619734 SCH-619734;Rolapitant(sch619734);rolapitant,914462-92-3
CBNumber:
CB12628366
Molecular Formula:
C25H26F6N2O2
Molecular Weight:
500.48
MDL Number:
MFCD23105917
MOL File:
552292-08-7.mol
Last updated:2023-09-04 15:51:00

Rolapitant Properties

Boiling point 523.5±50.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 3 mg/ml
pka 15.88±0.40(Predicted)
form Powder
FDA UNII NLE429IZUC
ATC code A04AD14

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

Rolapitant price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23906 Rolapitant ≥98% 552292-08-7 1mg $32 2024-03-01 Buy
Cayman Chemical 23906 Rolapitant ≥98% 552292-08-7 5mg $116 2024-03-01 Buy
Cayman Chemical 23906 Rolapitant ≥98% 552292-08-7 10mg $214 2024-03-01 Buy
AK Scientific 3912BB Rolapitant 552292-08-7 1mg $133 2021-12-16 Buy
ChemScene CS-6387 Rolapitant 98.43% 552292-08-7 10mg $150 2021-12-16 Buy
Product number Packaging Price Buy
23906 1mg $32 Buy
23906 5mg $116 Buy
23906 10mg $214 Buy
3912BB 1mg $133 Buy
CS-6387 10mg $150 Buy

Rolapitant Chemical Properties,Uses,Production

Definition

ChEBI: An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 115)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanxi Xuanran Import and Export Trade Co., Ltd.
+8617735180244 mike_yan@xuanranglobal.com CHINA 4022 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hong Kong Tiansheng New Material Trading Co., Ltd
+8617320695765 zxx@hktiansheng.com China 981 58

View Lastest Price from Rolapitant manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rolapitant pictures 2024-03-20 Rolapitant
552292-08-7
US $8.00 / g 1g 98% 500g Wuhan Topule Biopharmaceutical Co., Ltd
Rolapitant pictures 2023-03-24 Rolapitant
552292-08-7
US $35.00 / kg 1kg 99% 20 tons Hebei Duling International Trade Co. LTD
rolapitant pictures 2022-02-25 rolapitant
552292-08-7
US $45.99 / KG 1KG 99% 100KG Hong Kong Tiansheng New Material Trading Co., Ltd
  • Rolapitant pictures
  • Rolapitant
    552292-08-7
  • US $8.00 / g
  • 98%
  • Wuhan Topule Biopharmaceutical Co., Ltd
  • Rolapitant pictures
  • Rolapitant
    552292-08-7
  • US $35.00 / kg
  • 99%
  • Hebei Duling International Trade Co. LTD
  • rolapitant pictures
  • rolapitant
    552292-08-7
  • US $45.99 / KG
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd

Rolapitant Spectrum

Rolapitant (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride. Rolapitant HCl Rolapitant(sch619734) (5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one (5S,8S)-8-({(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one 1,7-Diazaspiro[4.5]decan-2-one,8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-,(5S,8S)- (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one Rolapitant-d4 SCH619734 Rolapitant USP/EP/BP Roltant 3-Tritetradecanoylglycerol brand name: Varubi SCH619734 SCH-619734 rolapitant,914462-92-3 foot tapping,long-acting,emesis,retches,Rolapitant,NK receptor,Neurokinin Receptor,vomits,SCH 619734,SCH-619734,anti-emetic,Inhibitor,inhibit,orally active,Mongolian Gerbils,Tachykinin receptor,ferret (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one 552292-08-7 C25H26F6N2O2