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ChemicalBook >> CAS DataBase List >>5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione Structure
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione structure
CAS No.
73326-98-4
Chemical Name:
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione
Synonyms
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione
CBNumber:
CB12645396
Molecular Formula:
C15H8N2O2
Molecular Weight:
248.24
MDL Number:
MFCD28953033
MOL File:
73326-98-4.mol
Last updated:2023-03-31 09:12:57
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5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione Properties

Melting point >300 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling point 543.0±40.0 °C(Predicted)
Density 1.506±0.06 g/cm3(Predicted)
pka 11.81±0.20(Predicted)

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione Chemical Properties,Uses,Production

Description

Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency than the current std. Drp1 GTPase inhibitor, mdivi-?1, (IC50 for mitochondrial fragmentation are (0.06, and 10 μM, resp.)?. Ellipticine quinone suppressed lung cancer tumor growth in a mouse xenograft model. Ellipticine quinone also inhibited mitochondrial ROS prodn., prevented mitochondrial fission, and improved right ventricular diastolic dysfunction during IR injury.

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione synthesis

1544198-71-1
73326-98-4
Synthesis of 5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione from 1H-Indole-3-carboxylic acid, 2-(4-pyridinylcarbonyl)-, ethyl ester

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione Preparation Products And Raw materials

Raw materials

1H-Indole-3-carboxylic acid, 2-(4-pyridinylcarbonyl)-, ethyl ester 1H-Indole-3-carboxylic acid, 2-(4-pyridinylcarbonyl)- 5H-Pyrido[4',3':5,6]oxepino[3,2-b]indol-5-one, 6,12-dihydro- 1H-Indole-2-carboxylic acid, 3-(3-pyridinylcarbonyl)-, ethyl ester N-(methoxymethyl)-3-indolecarboxaldehyde
sodiuM 2-(2-aMinophenyl)-2-oxoacetate Isatin Indole-3-carboxaldehyde Indole

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Preparation Products

5H-Pyrido[3,4-b]carbazole-5,11(10H)-dione

5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Ltstc Optoelectronics Technology Co., Ltd.. +86 029 88320727-808 China 119 58
Supplier Advantage
Shaanxi Ltstc Optoelectronics Technology Co., Ltd.. 58

73326-98-4(5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione)Related Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
5H-Pyrido[4,3-b]carbazole-5,11(6H)-dione 73326-98-4