ChemicalBook >> CAS DataBase List >>(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- CAS No.
- 327623-37-0
- Chemical Name:
- (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- Synonyms
- Aprepitant Impurity 1;Aprepitant Impurity 11;Fosaprepitant Impurity 30;Aprepitant M2 Metabolite Enantiomer;Aprepitant Impurity 1 Hydrochloride;Aprepitant Impurity 10 Hydrochloride;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1’Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- CBNumber:
- CB12657010
- Molecular Formula:
- C20H18F7NO2
- Molecular Weight:
- 437.35
- MDL Number:
- MFCD25976444
- MOL File:
- 327623-37-0.mol
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemical Properties,Uses,Production
Uses
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 40)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14335 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 5056 | 50 |
CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1785 | 58 | |
GIHI CHEMICALS CO.,LTD | 0086-571-86217390 | Sales@gihichem.com | China | 861 | 58 |
Shanghai Ranxon Chemical Co., Ltd. | 13148101715 | 2073632910@qq.com | China | 38 | 55 |
Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9798 | 50 |
327623-37-0((2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine)Related Search:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine
Aprepitant
Fosaprepitant dimeglumine
Aprepitant
Aprepitant
Aprepitant
Fosaprepitant Impurity 6
(2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
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(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
(2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine
Aprepitant Impurity 1
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant
Aprepitant Impurity 11
Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer
Fosaprepitant Impurity 30
Aprepitant Impurity 1 Hydrochloride
Aprepitant M2 Metabolite Enantiomer
Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-
Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1&rsquo
Aprepitant Impurity 10 Hydrochloride
327623-37-0