ChemicalBook >> CAS DataBase List >>4-Amino-3-chlorophenol

4-Amino-3-chlorophenol

CAS No.
17609-80-2
Chemical Name:
4-Amino-3-chlorophenol
Synonyms
4-amino-3-chloro-pheno;3-chloro-4-aminophenol;lenvaint-G;Brn 2802558;synthesis-023;synthesis-1-013;Einecs 241-583-3;4-AMINO-3-CHLOROPHENOL;lenvatinib intermediate;AMINO(4-)-3-CHLOROPHENOL
CBNumber:
CB1266045
Molecular Formula:
C6H6ClNO
Molecular Weight:
143.57
MDL Number:
MFCD00801116
MOL File:
17609-80-2.mol
MSDS File:
SDS
Last updated:2023-12-11 17:28:48

4-Amino-3-chlorophenol Properties

Melting point 159-160℃
Boiling point 287.3±25.0 °C(Predicted)
Density 1.406±0.06 g/cm3(Predicted)
RTECS SJ5710000
storage temp. 2-8°C(protect from light)
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
pka 9.26±0.18(Predicted)
color White
Stability Hygroscopic
CAS DataBase Reference 17609-80-2(CAS DataBase Reference)
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332-H335
Precautionary statements  P261-P280-P304+P340-P305+P351+P338-P405-P501a
HazardClass  6.1
HS Code  2922290090
NFPA 704
0
2 0

4-Amino-3-chlorophenol price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H66310 4-Amino-3-chlorophenol, 95% 17609-80-2 1g $293 2023-06-20 Buy
Alfa Aesar H66310 4-Amino-3-chlorophenol, 95% 17609-80-2 250mg $88.9 2021-12-16 Buy
TRC A601735 4-Amino-3-chlorophenol 17609-80-2 250mg $45 2021-12-16 Buy
TRC A601735 4-Amino-3-chlorophenol 17609-80-2 1g $55 2021-12-16 Buy
SynQuest Laboratories 4656-5-1F 4-Amino-3-chlorophenol 17609-80-2 5G $114 2021-12-16 Buy
Product number Packaging Price Buy
H66310 1g $293 Buy
H66310 250mg $88.9 Buy
A601735 250mg $45 Buy
A601735 1g $55 Buy
4656-5-1F 5G $114 Buy

4-Amino-3-chlorophenol Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Uses

4-Amino-3-Chlorophenol acts as a synthetic reagent for the preparation of Benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer''s disease treatment.

Application

The 4-amino-3-chlorophenol is a crucial intermediate for preparing a tyrosine kinase inhibitor, tivozanib, and a late liver cancer drug, lenvatinib. As a crucial pharmaceutical chemical intermediate, 4-amino-3-chlorophenol is widely applied to the design and synthesis of medicaments for resisting tumors, cardiovascular diseases, neurological diseases, and the like.

Synthesis

Starting from o-chloronitrobenzene with introducing hydroxyl groups in the presence of strong acids and molybdenum salts as catalysts could synthesize 4-amino-3-chlorophenol. Besides, using m-chlorophenol as a starting material and introducing hydroxyl on a benzene ring through diazotization and coupling also could synthesize 4-Amino-3-chlorophenol.

491-11-2
17609-80-2
Synthesis of 4-Amino-3-chlorophenol from 3-chloro-4-nitrophenol

4-Amino-3-chlorophenol Preparation Products And Raw materials

Global( 313)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Qiwei Pharmatech Co.,Ltd
13282840061 mw@qwpharmatech.com China 109 58
Jinan Million Pharmaceutical Co., Ltd
+86-531-68659554 +8613031714605 info@millionpharm.com China 153 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958 bj1@bj-chem.com China 298 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60

View Lastest Price from 4-Amino-3-chlorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Amino-3-chlorophenol pictures 2024-04-19 4-Amino-3-chlorophenol
17609-80-2
US $1.00-0.50 / kg 1kg 99% 200 Jinan Million Pharmaceutical Co., Ltd
4-Amino-3-chlorophenol pictures 2023-12-01 4-Amino-3-chlorophenol
17609-80-2
US $0.00-0.00 / kg 1kg ≥98% by HPLC 100kg Zison Pharmaceutical (Shandong) Co., Ltd.
4-Amino-3-chlorophenol pictures 2023-03-12 4-Amino-3-chlorophenol
17609-80-2
US $0.00 / kg 1kg 98.0%min 100kg LY Global chemicals co.,ltd .
AMINO(4-)-3-CHLOROPHENOL 4-AMINO-3-CHLOROPHENOL Brn 2802558 Einecs 241-583-3 Phenol, 4-amino-3-chloro- lenvaint-G lenvatinib intermediate synthesis-023 synthesis-1-013 3-chloro-4-aminophenol 4-amino-3-chloro-pheno 4-Amino-3-chlorophenol 17609-80-2 Lenvatinib Intermediate V 17609-80-2 17609-80-2