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2-AMino-5-chloro-4'-hydroxybenzophenone

2-AMino-5-chloro-4'-hydroxybenzophenone Structure
2-AMino-5-chloro-4'-hydroxybenzophenone structure
CAS No.
784-41-8
Chemical Name:
2-AMino-5-chloro-4'-hydroxybenzophenone
Synonyms
DIAZEPAM - IN HOUSE IMPURITY;2-AMino-5-chloro-4'-hydroxybenzophenone;Methanone, (2-amino-5-chlorophenyl)(4-hydroxyphenyl)-;(2-Amino-5-chloro-phenyl)-(4-hydroxy-phenyl)-methanone
CBNumber:
CB12709922
Molecular Formula:
C13H10ClNO2
Molecular Weight:
247.68
MDL Number:
MFCD22053716
MOL File:
784-41-8.mol
Last updated:2023-07-12 08:29:12
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2-AMino-5-chloro-4'-hydroxybenzophenone Properties

Melting point 174°C
solubility soluble in DCM, Ethyl Acetate
form Solid
color Yellow

2-AMino-5-chloro-4'-hydroxybenzophenone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A603980 2-Amino-5-chloro-4''-hydroxybenzophenone 784-41-8 100mg $580 2021-12-16 Buy
Medical Isotopes, Inc. 43010 2-Amino-5-chloro-4??-hydroxybenzophenone 784-41-8 25mg $675 2021-12-16 Buy
Product number Packaging Price Buy
A603980 100mg $580 Buy
43010 25mg $675 Buy

2-AMino-5-chloro-4'-hydroxybenzophenone Chemical Properties,Uses,Production

Uses

2-Amino-5-chloro-4'-hydroxybenzophenone is an intermediate in the preparation of Diazepam (D416855), an anxiolytic agent, muscle relaxant and anticonvulsant agent.

Preparation

Preparation by cleavage of 5-chloro-3-(phydroxyphenyl)- 2,1-benzisoxazole (other name: 5-chloro-3-(p-hydroxy-phenyl)anthranil) (SM),
? by heating at reflux with aluminium iodide for 50 min (87%);
? by reaction with concentrated hydrochloric acid and an excess of tin in boiling ethanol or acetic acid. SM (m.p. 241°) was prepared by condensation of o-nitrobenzaldehyde with phenol in the presence of hydrogen chloride or phosphorous oxychloride in cold acetic acid;
? by hydrogenation in the presence of 10% Pd/C in ethyl acetate between 40° and 60° at a pressure of 3 atmospheres (quantitative yield).

2-AMino-5-chloro-4'-hydroxybenzophenone synthesis

67445-85-6
784-41-8
Synthesis of 2-AMino-5-chloro-4'-hydroxybenzophenone from 5-Chloro-3-(4-hydroxyphenyl)-2,1-benzisoxazole

2-AMino-5-chloro-4'-hydroxybenzophenone Preparation Products And Raw materials

Raw materials

Preparation Products

2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide

2-AMino-5-chloro-4'-hydroxybenzophenone Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 2918 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55672 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Supplier Advantage
sgtlifesciences pvt ltd 		58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Cochemical Ltd. 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Energy Chemical 58
2-AMino-5-chloro-4'-hydroxybenzophenone Methanone, (2-amino-5-chlorophenyl)(4-hydroxyphenyl)- DIAZEPAM - IN HOUSE IMPURITY (2-Amino-5-chloro-phenyl)-(4-hydroxy-phenyl)-methanone 784-41-8