1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)
- CAS No.
- 799279-67-7
- Chemical Name:
- 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt)
- Synonyms
- C18 LPA;1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt);1-O-OCTADECYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE (AMMONIUM SALT);C18 LPA
- CBNumber:
- CB12720763
- Molecular Formula:
- C21H48NO6P
- Molecular Weight:
- 441.59
- MDL Number:
- MFCD22416844
- MOL File:
- 799279-67-7.mol
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Chemical Properties,Uses,Production
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
General Description
Lysophosphatidic?acid (LPA) is a class of phospholipids, which is water-soluble. It has a glycerol backbone attached?via?a phosphate group, an aliphatic chain and a hydroxyl group.?The aliphatic chain is linked to either?sn-1 or?sn-2 position and the phosphate group is connected to the?sn-3 position. The hydroxyl group is linked to the remaining?sn-1 or?sn-2?position.
Biochem/physiol Actions
Lysophosphatidic?acid (LPA) is a signaling molecule and alters various cellular responses through G protein-coupled receptors (GPCRs). It stimulates smooth muscle contraction, cytoskeleton rearrangement and chemotaxis. LPA is also involved in inducing neurotransmitter release, cell proliferation, platelet aggregation and Ca2+ mobilization. Increased levels of LPA in human plasma leads to ovarian cancer and atherosclerosis. LPA acts as a potential biomarker for ovarian cancer.
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate (aMMoniuM salt) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17698 | 55 |
Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14623 | 60 |
Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29803 | 58 |
Supplier | Advantage |
---|---|
Creative Enzymes | 58 |
Sigma-Aldrich | 80 |
Codow Chemical Co.,Ltd. | 55 |
Chengdu Dianchun Technology Co., Ltd | 60 |
Shanghai Maclean Biochemical Technology Co., LTD | 58 |