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DIFLUOROACETIC ANHYDRIDE

DIFLUOROACETIC ANHYDRIDE structure

CAS No.: 401-67-2

Chemical Name:: DIFLUOROACETIC ANHYDRIDE

Synonyms: 2,2-difluoroacetic anhydride;DIFLUOROACETIC ANHYDRIDE;DifluoroaceticAnhydride>DIFLUOROACETIC ACID ANHYDRIDE;2,2-Difluoro-acetic acid 1,1'-anhydride;1,1,5,5-Tetrafluoro-3-oxapentan-2,4-dione;Acetic acid,2,2-difluoro-, 1,1'-anhydride;2,2-difluoroacetic acid (2,2-difluoro-1-oxoethyl) ester

CBNumber:: CB1274448

Molecular Formula:: C4H2F4O3

Molecular Weight:: 174.05

MDL Number:: MFCD02093315

MOL File:: 401-67-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:23:31

Product description	Number	Pack Size	Price
Difluoroacetic Anhydride >98.0%(GC)	D4164	5g	$87
Difluoroacetic anhydride 97%	PC3791	5g	$25
Difluoroacetic anhydride 97%	PC3791	25g	$55
Difluoroacetic anhydride 97%	PC3791	100g	$143
Difluoroacetic anhydride 97%	PC3791	5g	$25
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DIFLUOROACETIC ANHYDRIDE Properties

Boiling point	94℃
Density	1.4
refractive index	1.3410-1.3450
Flash point	11℃
form	clear liquid
color	Colorless to Light yellow to Light orange
Specific Gravity	1.59
InChI	InChI=1S/C4H2F4O3/c5-1(6)3(9)11-4(10)2(7)8/h1-2H
InChIKey	QNRXDQIHPGZCFB-UHFFFAOYSA-N
SMILES	C(=O)(C(F)F)OC(=O)C(F)F
CAS DataBase Reference	401-67-2

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H227-H290-H314

Precautionary statements

P210-P234-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P403+P235-P405-P406-P501

Hazard Codes

RIDADR

3265

HazardClass

CORROSIVE

PackingGroup

HS Code

29189900

Limited Quantities

1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

NFPA 704

	4
3		0

DIFLUOROACETIC ANHYDRIDE price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D4164	Difluoroacetic Anhydride >98.0%(GC)	401-67-2	5g	$87	2026-04-30	Buy
Apolloscientific	PC3791	Difluoroacetic anhydride 97%	401-67-2	5g	$25	2026-06-04	Buy
Apolloscientific	PC3791	Difluoroacetic anhydride 97%	401-67-2	25g	$55	2026-06-04	Buy
Apolloscientific	PC3791	Difluoroacetic anhydride 97%	401-67-2	100g	$143	2026-06-04	Buy
Apolloscientific	PC3791	Difluoroacetic anhydride 97%	401-67-2	5g	$25	2026-06-04	Buy

Product number	Packaging	Price	Buy
D4164	5g	$87	Buy
PC3791	5g	$25	Buy
PC3791	25g	$55	Buy
PC3791	100g	$143	Buy
PC3791	5g	$25	Buy

DIFLUOROACETIC ANHYDRIDE Chemical Properties,Uses,Production

Application

Difluoroacetic anhydride is mainly used as an acylation reagent in organic synthesis to introduce difluoroacetyl groups. Difluoroacetate is mainly used as an intermediate in pesticides, pharmaceuticals, and fluorine-containing fine chemicals, and can also be used as a solvent in lithium battery electrolytes.

Chemical Properties

Light yellow liquid

Synthesis

1. Difluoroacetic acid reacts with phosphorus pentoxide. Distillation yields difluoroacetic anhydride.
2. More difluoroacetic acid is added to the residue from step 1. Distillation gives a mixture containing the anhydride.
3. Difluoroacetic acid and methanol are added to the residue from step 2. Distillation yields methyl difluoroacetate.
4. The mixture from step 2 is reacted with phosphorus pentoxide. Distillation yields more difluoroacetic anhydride.

DIFLUOROACETIC ANHYDRIDE synthesis

Synthesis of DIFLUOROACETIC ANHYDRIDE from Difluoroacetic acid

DIFLUOROACETIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-Difluoromethyl-1H-benzoimidazole 1-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-2,2-difluoroethanone 6-CHLORO-3-(TRIFLUOROMETHYL)[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE

DIFLUOROACETIC ANHYDRIDE Suppliers

Global( 183)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9333	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16512	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	28755	58

Supplier	Advantage
Henan Aochuang Chemical Co.,Ltd.	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Antai Fine Chemical Technology Co.,Limited	58
Longyan Tianhua Biological Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58

View Lastest Price from DIFLUOROACETIC ANHYDRIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-06	DIFLUOROACETIC ANHYDRIDE 401-67-2	$80.00-800.00	10kg	0.99	20tons	Zibo Hangyu Biotechnology Development Co., Ltd
2026-07-02	Difluoroacetic anhydride 401-67-2	$3.00-9.00		99%		ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-06-30	DIFLUOROACETIC ANHYDRIDE 401-67-2		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

DIFLUOROACETIC ANHYDRIDE
401-67-2
$80.00-800.00
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

Difluoroacetic anhydride
401-67-2
$3.00-9.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

DIFLUOROACETIC ANHYDRIDE
401-67-2
98.0%
Shaanxi Dideu New Materials Co. Ltd

DIFLUOROACETIC ANHYDRIDE Spectrum

DIFLUOROACETIC ANHYDRIDE(401-67-2)¹HNMR

401-67-2(DIFLUOROACETIC ANHYDRIDE)Related Search:

Chlorodifluoroacetic acid ethyl ester Difluoroacetic acid Trifluoroacetic anhydride CHLORODIFLUOROACETIC ANHYDRIDE PERFLUOROHEPTANOIC ANHYDRIDE

PERFLUOROPENTANOIC ANHYDRIDE Perfluoropropionic anhydride HEXAFLUOROGLUTARIC ANHYDRIDE TETRAFLUOROSUCCINIC ANHYDRIDE Heptafluorobutyric anhydride

DIFLUOROACETIC ANHYDRIDE PERFLUOROOCTANOIC ANHYDRIDE

1of3

2,2-Difluoro-acetic acid 1,1'-anhydride 1,1,5,5-Tetrafluoro-3-oxapentan-2,4-dione DIFLUOROACETIC ANHYDRIDE DIFLUOROACETIC ACID ANHYDRIDE 2,2-difluoroacetic acid (2,2-difluoro-1-oxoethyl) ester DifluoroaceticAnhydride> Acetic acid,2,2-difluoro-, 1,1'-anhydride 2,2-difluoroacetic anhydride 401-67-2