ChemicalBook >> CAS DataBase List >>NSC 150117 hydrochloride
NSC 150117 hydrochloride
- CAS No.
- 95130-23-7
- Chemical Name:
- NSC 150117 hydrochloride
- Synonyms
- (E/Z)-BCI;BCI (hydrochloride);(E)-BCI hydrochloride;(E/Z)-BCI hydrochloride;NSC 150117 hydrochloride;BCI hydrochloride - NSC 150117 hydrochloride;(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one;2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride;(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one;3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
- CBNumber:
- CB12756032
- Molecular Formula:
- C22H24ClNO
- Molecular Weight:
- 353.885
- MDL Number:
- MFCD16875416
- MOL File:
- 95130-23-7.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
NSC 150117 hydrochloride price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B4313 | (E/Z)-BCI hydrochloride ≥98% (HPLC) | 95130-23-7 | 5mg | $247 | 2024-03-01 | Buy |
| Sigma-Aldrich | B4313 | (E/Z)-BCI hydrochloride ≥98% (HPLC) | 95130-23-7 | 25mg | $579.6 | 2024-03-01 | Buy |
| Cayman Chemical | 21945 | BCI (hydrochloride) ≥95% | 95130-23-7 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 21945 | BCI (hydrochloride) ≥95% | 95130-23-7 | 5mg | $202 | 2024-03-01 | Buy |
| Cayman Chemical | 21945 | BCI (hydrochloride) ≥95% | 95130-23-7 | 10mg | $384 | 2024-03-01 | Buy |
NSC 150117 hydrochloride Chemical Properties,Uses,Production
Uses
(E/Z)-BCI hydrochloride has been used:
- to evaluate the role of the Duox-H2O2-Dusp6 derepression signaling pathway in heart regeneration
- as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
- as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells
Biochem/physiol Actions
BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.
NSC 150117 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
NSC 150117 hydrochloride Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3538 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
(E/Z)-BCI hydrochloride
2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride
3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
NSC 150117 hydrochloride
BCI (hydrochloride)
(E/Z)-BCI
BCI hydrochloride - NSC 150117 hydrochloride
(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
(E)-BCI hydrochloride
95130-23-7