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Ginsenoside Rd

Ginsenoside Rd structure

CAS No.: 52705-93-8

Chemical Name:: Ginsenoside Rd

Synonyms: Chikusetsusaponin FK7;Gypenoside VIII;ginsenosideR;Panaxoside Rd;GINSENOSIDE RD;GINSENOOSIDERD;Sanchinoside Rd;Rd Ginsenoside Rd;Ginsenoside Rd-RM;Ginsenoside Rd(AS)

CBNumber:: CB1281187

Molecular Formula:: C48H82O18

Molecular Weight:: 947.15

MDL Number:: MFCD00799993

MOL File:: 52705-93-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Ginsenoside Rd ≥98% (HPLC)	SML4126	10 mg	$106
Ginsenoside Rd ≥98% (HPLC)	SML4126	50 mg	$320
Ginsenoside Rd phyproof? Reference Substance	PHL89211	10MG	$232
Ginsenoside Rd analytical standard	01518	10mg	$317
Ginsenoside Rd ≥98% (HPLC)	SML4126	1 unit	$94.05
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Ginsenoside Rd Properties

Melting point	204～206℃
Boiling point	1015.6±65.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	12.85±0.70(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic
Cosmetics Ingredients Functions	ANTIOXIDANT
InChIKey	FBFMBWCLBGQEBU-FIKSETHBNA-N
LogP	3.110 (est)
CAS DataBase Reference	52705-93-8(CAS DataBase Reference)
FDA UNII	WB232T95AV
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P501

Hazard Codes

Risk Statements

Safety Statements

2-45

WGK Germany

HS Code

29389090

NFPA 704

	0
2		0

Ginsenoside Rd price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML4126	Ginsenoside Rd ≥98% (HPLC)	52705-93-8	10 mg	$106	2026-04-30	Buy
Sigma-Aldrich	SML4126	Ginsenoside Rd ≥98% (HPLC)	52705-93-8	50 mg	$320	2026-04-30	Buy
Sigma-Aldrich	PHL89211	Ginsenoside Rd phyproof? Reference Substance	52705-93-8	10MG	$232	2026-04-30	Buy
Sigma-Aldrich	01518	Ginsenoside Rd analytical standard	52705-93-8	10mg	$317	2026-04-30	Buy
Sigma-Aldrich	SML4126	Ginsenoside Rd ≥98% (HPLC)	52705-93-8	1 unit	$94.05	2025-07-31	Buy

Product number	Packaging	Price	Buy
SML4126	10 mg	$106	Buy
SML4126	50 mg	$320	Buy
PHL89211	10MG	$232	Buy
01518	10mg	$317	Buy
SML4126	1 unit	$94.05	Buy

Ginsenoside Rd Chemical Properties,Uses,Production

Description

Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities.

Chemical Properties

White to off-white crystals powder

Uses

Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.

Definition

ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.

in vivo

Ginsenosides Rd is a major compound isolated from Gynostemma pentaphyllum that holistically improves gut microenvironment and induces anti-polyposis in Apc^Min/+ mice. Six-weeks-old mice are subjected to Ginsenoside Rd treatment, before the appearance of the intestinal polyps. All the mice are monitored for food intake, water consumption, and weight changes. Throughout the experiment, no Rb3/ Ginsenoside Rd-associated weight loss in mice is observed. In addition, none of the treated mice show variations in food and water consumption. Whereas, the number and size of the polyps are effectively reduced by Ginsenoside Rd treatments^[3].

IC 50

NF-κB: 12.05 μM (IC₅₀, in HepG2 cells); COX-2; L-type calcium channel; CYP2D6: 58 μM (IC₅₀); CYP1A2: 78.4 μM (IC₅₀); CYP3A4: 81.7 μM (IC₅₀); CYP2C9: 85.1 μM (IC₅₀)

References

[1] CHIEH-FU CHEN Jun tian Z Wen fei Chiou. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium[J]. Acta Pharmacologica Sinica, 2008, 29 9: 1103-1108. DOI: 10.1111/j.1745-7254.2008.00868.x
[2] YANG WANG. Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway.[J]. PLoS ONE, 2013: e70956. DOI: 10.1371/journal.pone.0070956
[3] X. LIU. Ginsenoside-Rd improves outcome of acute ischaemic stroke – a randomized, double-blind, placebo-controlled, multicenter trial[J]. European Journal of Neurology, 2012, 19 6: 855-863. DOI: 10.1111/j.1468-1331.2011.03634.x
[4] SEOK BEAN SONG. Inhibition of TNF-α-mediated NF-κB Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves.[J]. Journal of Ginseng Research, 2012, 36 2: 146-152. DOI: 10.5142/jgr.2012.36.2.146

Ginsenoside Rd Preparation Products And Raw materials

Raw materials

Preparation Products

Ginsenoside Rd Suppliers

Global( 376)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618791163155	18791163155@163.com	China	3397	58
Shaanxi Xianhe Biotech Co., Ltd	+86-17709210191; +8617709210191	Jerry@xhobio.com	China	906	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	1287	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	+8613815430202	sale02@cqherb.com	CHINA	376	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58

Supplier	Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58
Shaanxi Xianhe Biotech Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	58
BOC Sciences	58
Shanghai Standard Technology Co., Ltd.	58

The Role of Ginsenoside Rd in Neurological Diseases
Ginsenoside Rd crosses the blood-brain barrier and exerts neuroprotective effects via anti-inflammatory, anti-apoptotic pathwa....
Feb 12，2026

View Lastest Price from Ginsenoside Rd manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	GINSENOSIDE Rd 52705-93-8	US $0.00 / kg	1kg	0.99	1000kg	Shaanxi Xianhe Biotech Co., Ltd
2026-04-22	Ginsenoside Rd 52705-93-8	US $33.00-106.00 / mg		99.50%	10g	TargetMol Chemicals Inc.
2023-02-24	Ginsenoside Rd 52705-93-8	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.

GINSENOSIDE Rd
52705-93-8
US $0.00 / kg
0.99
Shaanxi Xianhe Biotech Co., Ltd

Ginsenoside Rd
52705-93-8
US $33.00-106.00 / mg
99.50%
TargetMol Chemicals Inc.

Ginsenoside Rd
52705-93-8
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Ginsenoside Rd Spectrum

Ginsenoside Rd(52705-93-8)¹HNMR

52705-93-8(Ginsenoside Rd)Related Search:

Ginsenoside Rh2 Ginsenoside Re Ginsenoside Rg1 Ginsenoside Rb1 Ginseng extract

20(R)-Ginsenoside Rg3 TRIBULOSIDE GINSENOSIDE RE Ginsenoside Rh1 Ginsenoside Rf

GINSENOSIDEF1 Ginsenoside-Rg5 Ginsenoside Rb3 Ginsenoside Rk3 Ginsenoside Rg2

GINSENOSIDE RB2 GinsenosideRo Ginsenoside Rc

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2-o-beta-d-glucopyranosyl-(3beta,12beta)-20-(beta-d-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-d-glucopyranoside GINSENOSIDE RD beta-d-glucopyranoside,(3-beta,12-beta)-20-(beta-d-glucopyranosyloxy)-12-hydro (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside xydammar-24-en-3-yl2-o-beta-d-glucopyranosyl- GINSENOOSIDERD Ginsenoside Rd (CAS# 52705-93-87) GINSENOSIDE Rd hplc Ginsenoside Rd std. GINSENOSIDE RD WITH HPLC (20S)-3β-[[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy]-20-(β-D-glucopyranosyloxy)dammaran-24-ene-12β-ol (20S)-3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol [20-(β-D-Glucopyranosyloxy)-12β-hydroxydammar-24-en-3β-yl]2-O-β-D-glucopyranosyl-β-D-glucopyranoside 20-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-ene-3β-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside 3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol ginsenoside--Rd standard Ginsenoside Rd ,98% Herba Gynostemmatis Pentaphylli glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl2-O-β-D-glucopyranosyl- β-D-Glucopyranoside,(3β,12β)-20-(β-D- Ginsenoside Rd 52705-93-8 b-D-Glucopyranoside, (3b,12b)-20-(b-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-b-D-glucopyranosyl- Panaxoside Rd Sanchinoside Rd β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl- ginsenosideR 2-O-beta-Glucopyranosyl-(3beta,12beta)-20-beta-D-glucopyranosyloxy-12-hydroxydammar-24-en-3-yl-beta-D-glucopyranoside (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chikusetsusaponin FK7 Gypenoside VIII (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Rd Ginsenoside Rd Ginsenoside Rd(AS) Ginsenoside Rd-RM β-?D-?Glucopyranoside, (3β,?12β)?-?20-?(β-?D-?glucopyranosyloxy)?-?12-?hydroxydammar-?24-?en-?3-?yl 2-?O-?β-?D-?glucopyranosyl- 52705-93-8 C48H82O19 Inhibitors reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Ginsenoside series chemical reagent pharmaceutical intermediate phytochemical The group of Ginsenosides Saponins