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RO-31-7549

RO-31-7549 Structure
RO-31-7549 structure
CAS No.
125313-65-7
Chemical Name:
RO-31-7549
Synonyms
RO-31-7549;RO 31-7549 ACETATE SALT;Bisindolylmaleimide VIII;BISINDOLYLMALEIMIDE VIII ACETATE;BIDINDOLYLMALEIMIDE VIII, ACETETE;Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem;2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-
CBNumber:
CB1281637
Molecular Formula:
C24H22N4O2
Molecular Weight:
398.46
MDL Number:
MOL File:
125313-65-7.mol
Last updated:2023-04-23 13:52:06
Request For Quotation

RO-31-7549 Properties

storage temp. −20°C
solubility DMSO: soluble
form Red to reddish-orange solid
FDA UNII Y6197FQK8I

SAFETY

Risk and Safety Statements

WGK Germany  3

RO-31-7549 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 557508 Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem
A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. 		125313-65-7 1mg $216 2024-03-01 Buy
Usbiological 044608 Bisindolylmaleimide VIII acetate 125313-65-7 1mg $286 2021-12-16 Buy
Product number Packaging Price Buy
557508 1mg $216 Buy
044608 1mg $286 Buy

RO-31-7549 Chemical Properties,Uses,Production

Uses

It is a potent inhibitor of protein kinase C (PKC) activity.

General Description

A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Does not inhibit the tyrosine phosphorylation or the activation of phospholipase Cγ1. Exhibits some degree of PKC isozyme specificity (IC50 = 53 nM for PKCα, 195 nM for PKCβI, 163 nM for PKCβII, 213 nM for PKCγ, and 175 nM for PKCε). Inhibits carbachol-evoked noradrenaline release (IC50 = 600 nM).

Biochem/physiol Actions

Cell permeable: yes

RO-31-7549 Preparation Products And Raw materials

Raw materials

Preparation Products

RO-31-7549 Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55591 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
J & K SCIENTIFIC LTD. 76
Chemsky (shanghai) International Co.,Ltd 60
Sigma-Aldrich 80
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Energy Chemical 58

125313-65-7(RO-31-7549)Related Search:

Bisindolylmaleimide V RO 31-7549, IMMOBILIZED RO 31-7549 ACETATE 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione 3-Isopropenyl-1-methyl-1H-pyrrole
RO-31-7549

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BISINDOLYLMALEIMIDE VIII ACETATE 1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)- 3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Bisindolylmaleimide VIII 2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE RO-31-7549 RO 31-7549 ACETATE SALT BIDINDOLYLMALEIMIDE VIII, ACETETE Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem 125313-65-7 C24H22N4O2C2H4O2 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators