MYELIN BASIC PROTEIN ANTIGEN
- CAS No.
- Chemical Name:
- MYELIN BASIC PROTEIN ANTIGEN
- Synonyms
- MYELIN BASIC PROTEIN ANTIGEN;Myelin Basic Protein Antigen from human brain
- CBNumber:
- CB1282508
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03457654
- MOL File:
- Mol file
MYELIN BASIC PROTEIN ANTIGEN Chemical Properties,Uses,Production
Uses
Myelin basic protein antigen from human brain has been used in enzyme-linked immunosorbent spot assays.
General Description
Myelin basic protein (MBP) is an 18.5kDa protein encoded by the gene mapped to human chromosome 18q22qter. MBP is a major component of myelin sheath and is highly expressed in central nervous system (CNS).
Biochem/physiol Actions
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). It also has a crucial role to play in human demyelinating diseases including multiple sclerosis (MS). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis.
MYELIN BASIC PROTEIN ANTIGEN Preparation Products And Raw materials
Raw materials
Preparation Products
MYELIN BASIC PROTEIN ANTIGEN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |