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Triclabendazole

CAS No.
68786-66-3
Chemical Name:
Triclabendazole
Synonyms
Triclabendazol;Tricalbendazole;6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE;FASINEX;CGA-89317;snalvbendaz;TRICLABENDAZOLE;CGA-89317, Egaten;Triclabendazole EP;Triclabendazole CRS
CBNumber:
CB1282896
Molecular Formula:
C14H9Cl3N2OS
Molecular Weight:
359.66
MDL Number:
MFCD00864519
MOL File:
68786-66-3.mol
MSDS File:
SDS
Last updated:2024-04-25 17:59:01

Triclabendazole Properties

Melting point 175-176°C
Boiling point 240.6°C (rough estimate)
Density 1.3875 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Acetonitrile (Slightly, Sonicated), Methanol (Slightly)
pka 7.91±0.10(Predicted)
color White to Beige
Merck 14,9652
BCS Class 4/3
Stability Stability
InChI InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
InChIKey NQPDXQQQCQDHHW-UHFFFAOYSA-N
SMILES C1(SC)NC2=CC(Cl)=C(OC3=CC=CC(Cl)=C3Cl)C=C2N=1
CAS DataBase Reference 68786-66-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 4784C8E03O
ATC code P02BX04

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
RTECS  DD6747000
HS Code  29339900
Toxicity LD50 oral in rabbit: 206mg/kg
NFPA 704
1
2 0

Triclabendazole price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001737 Triclabendazole EuropePharmacopoeia (EP) Reference Standard 68786-66-3 y0001737 $153 2024-03-01 Buy
Sigma-Aldrich Y0001723 Triclabendazole for system suitability EuropePharmacopoeia (EP) Reference Standard 68786-66-3 y0001723 $153 2024-03-01 Buy
TCI Chemical T2826 Triclabendazole >98.0%(HPLC)(T) 68786-66-3 1g $29 2024-03-01 Buy
TCI Chemical T2826 Triclabendazole >98.0%(HPLC)(T) 68786-66-3 5g $79 2024-03-01 Buy
Cayman Chemical 18883 Triclabendazole ≥98% 68786-66-3 1g $72 2024-03-01 Buy
Product number Packaging Price Buy
Y0001737 y0001737 $153 Buy
Y0001723 y0001723 $153 Buy
T2826 1g $29 Buy
T2826 5g $79 Buy
18883 1g $72 Buy

Triclabendazole Chemical Properties,Uses,Production

Description

Triclabendazole is a benzimidazole anthelmintic. It eliminates both immature and adult flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg. Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.

Chemical Properties

Off-White Solid

Uses

An anthelmintic (fasciola).

Uses

Triclabendazole is classified under the category of ‘Anthelmintic flukicide for veterinary use.

Definition

ChEBI: 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole is an aromatic ether.

68828-69-3
74-88-4
68786-66-3
Synthesis of Triclabendazole from 5-chloro-6-(2,3-dichorophenoxy)-2-thio-1H-benzimidazole and Iodomethane

Triclabendazole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 391)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Langyou International Trading Co., Ltd
+8618874586545 linda@xrdchem.cn China 197 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850 hbjbtech@163.com China 1000 58
Wuhan Xinhao Biotechnology Co., Ltd
+86-18120578002 +86-18120578002 xinhao-6@xinhaoshengwu.com China 350 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 874 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

Related articles

View Lastest Price from Triclabendazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Triclabendazole pictures 2024-04-25 Triclabendazole
68786-66-3
US $1.00 / KG 1KG 99.91% 200000 Ouhuang Engineering Materials (Hubei) Co., Ltd
6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole pictures 2024-04-25 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
68786-66-3
US $6.00 / KG 1KG More than 99% 2000KG/Month Hebei Saisier Technology Co., LTD
Triclabendazole pictures 2024-04-09 Triclabendazole
68786-66-3
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
  • Triclabendazole pictures
  • Triclabendazole
    68786-66-3
  • US $1.00 / KG
  • 99.91%
  • Ouhuang Engineering Materials (Hubei) Co., Ltd

Triclabendazole Spectrum

FASINEX CGA-89317 5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-1H-BENZIMIDAZOLE TRICLABENDAZOLE 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1h-benzimidazol 5-Chloro-6-(2,3-dichlorophenoxy)-2-methylthio-1H-benzimidazole, CGA-89317, Fasinex 1H-Benzimidazole, 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)- 5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLTHIO)-1H-BENZIMIDAZOL(TRICLABENDAZOLE) 6-Chloro-5-(2,3-dichlorophenoxy)-2-(Methylthio)-1H-benzo[d]iMidazole 5-Chloro-6-(2,3-dichlorophenoxy)-2-MethylthiobenziMidazole CGA-89317, Egaten 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole 6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole 1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)- 5-Chloro-6 (2,3-Dichlorophenoxy)-2- Methylthio-1H- Bezimidazole Triclabendazole for system suitability 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole snalvbendaz Triclabendazole Standard Triclabendazole CRS Triclabendazole for system suitability CRS 6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzoimidazole Triclabendazole USP/EP/BP Triclabendazole (CGA89317) Triclabendazole (Y0001737) 6-CHLORO-5-(2,3-DICHLOROPHENOXY)-2-METHYLTHIO-BENZIMIDAZOLE Tricalbendazole Triclabendazol Triclabendazole EP Triclabendazole API Trichlorobenzimidazole Triclabendazole (25 mg) 68786-66-3 68788-66-3 68766-86-3 168786-66-3 C14H19Cl3N2OS C14H9Cl3N2OS Veterinary drugs APIs Intermediates & Fine Chemicals Pharmaceuticals API's Pharmaceutical intermediate 68786-66-3