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AG 825

AG 825 structure

CAS No.: 149092-50-2

Chemical Name:: AG 825

Synonyms: AG 825;Zinc02572484;TYRPHOSTIN C15;AG 825 USP/EP/BP;TYRPHOSTIN AG 825;AG 825 (Tyrphostin AG 825);AG 825 - CAS 149092-50-2 - Calbiochem;4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE;5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE;5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE

CBNumber:: CB1283828

Molecular Formula:: C19H15N3O3S2

Molecular Weight:: 397.47

MDL Number:: MFCD01074971

MOL File:: 149092-50-2.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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AG 825 Properties

storage temp.	−20°C
solubility	DMSO: soluble
form	Yellow solid
Sensitive	Light Sensitive

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

AG 825 price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T5443	Tyrphostin AG 825 ≥92.5%	149092-50-2	2mg	$52.8	2024-03-01	Buy
Sigma-Aldrich	121765	AG 825	149092-50-2	2mg	$172	2024-03-01	Buy
Alfa Aesar	J65227	Tyrphostin C15	149092-50-2	10mg	$233.65	2024-03-01	Buy
Cayman Chemical	10010243	AG 825 ≥98%	149092-50-2	1mg	$28	2024-03-01	Buy
Cayman Chemical	10010243	AG 825 ≥98%	149092-50-2	5mg	$90	2024-03-01	Buy

Product number	Packaging	Price	Buy
T5443	2mg	$52.8	Buy
121765	2mg	$172	Buy
J65227	10mg	$233.65	Buy
10010243	1mg	$28	Buy
10010243	5mg	$90	Buy

AG 825 Chemical Properties,Uses,Production

Uses

A selective ErbB2 inhibitor

Uses

AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.

Definition

ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

Biological Activity

Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

storage

Store at +4°C

AG 825 Preparation Products And Raw materials

Raw materials

Preparation Products

AG 825 Suppliers

Global( 90)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29322	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Suzhou Chireach Biomedical Technology Co., Ltd.	0512-65856968	sales@chireach.com	China	60	70
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9664	60
Synchem OHG	+49 5662 408730	info@synchem.de	Germany	4708	70

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Suzhou Chireach Biomedical Technology Co., Ltd.	70
VDM Biochemicals	64
Spectrum Chemical Manufacturing Corp.	60
Synchem OHG	70

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TYRPHOSTIN AG 825 TYRPHOSTIN C15 AG 825 5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE 5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE 4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE 3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- 2-Propenamide Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide AG 825 (Tyrphostin AG 825) (E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE Zinc02572484 AG 825 USP/EP/BP 2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- AG 825 - CAS 149092-50-2 - Calbiochem 149092-50-2 Cell Signaling and Neuroscience Cell Biology BioChemical Kinase/Phosphatase Biology Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) Protein Kinase