1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
- CAS No.
- 214701-49-2
- Chemical Name:
- 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
- Synonyms
- 1-(5-Bromopyridin-2-yl)ethan-1-one;5-Bromo-2-acetopyridine;2-Acetyl-5-bromopyridine;5-BROMO-2-ACETYLPYRIDINE;2-Acetyl-5-bromopyridine 98%;1-(5-Bromo-2-pyridyl)ethanone;1-(5-bromo-2-pyridinyl)ethanone;1-(5-Bromopyridine-2-yl)ethanone;1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE;Ethanone, 1-(5-broMo-2-pyridinyl)-
- CBNumber:
- CB1288999
- Molecular Formula:
- C7H6BrNO
- Molecular Weight:
- 200.03
- MDL Number:
- MFCD04974523
- MOL File:
- 214701-49-2.mol
| Product description | Number | Pack Size | Price |
| 1-(5-Bromo-2-pyridyl)ethanone | B679130 | 10g | $280 |
| 2-Acetyl-5-bromopyridine | FA46381 | 2g | $300 |
| 2-Acetyl-5-bromopyridine | OR51752 | 10g | $301 |
| 2-Acetyl-5-bromopyridine 98% | 4H17-9-X4 | 10g | $332 |
| 2-Acetyl-5-bromopyridine | OR51752 | 5g | $186 |
| More product size | |||
| Melting point | 112 °C |
|---|---|
| Boiling point | 257.2±25.0 °C(Predicted) |
| Density | 1.534±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | Solid |
| pka | 0?+-.0.10(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C7H6BrNO/c1-5(10)7-3-2-6(8)4-9-7/h2-4H,1H3 |
| InChIKey | IDZRAUUUHXQGKC-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=NC=C(Br)C=C1)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P280-P271 |
| HS Code | 2933399990 |
1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B679130 | 1-(5-Bromo-2-pyridyl)ethanone | 214701-49-2 | 10g | $280 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA46381 | 2-Acetyl-5-bromopyridine | 214701-49-2 | 2g | $300 | 2021-12-16 | Buy |
| Apolloscientific | OR51752 | 2-Acetyl-5-bromopyridine | 214701-49-2 | 10g | $301 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H17-9-X4 | 2-Acetyl-5-bromopyridine 98% | 214701-49-2 | 10g | $332 | 2021-12-16 | Buy |
| Apolloscientific | OR51752 | 2-Acetyl-5-bromopyridine | 214701-49-2 | 5g | $186 | 2021-12-16 | Buy |
1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE Chemical Properties,Uses,Production
Uses
1-(5-Bromo-2-pyridyl)ethanone is a reagent used to synthesize substituted pyridin-3-yl)phenyloxazolidinones as antibacterial agents with reduced activity against monoamine oxidase A.
Synthesis
624-28-2
127-19-5
214701-49-2
2,5-Dibromopyridine (I-1-1) 8 g (33.7 mmol) was stirred with 337 mL of toluene at -40 °C in a nitrogen atmosphere. After stirring for 40 min, 21.4 mL (1.02 eq.) of a hexane solution of 1.6 M n-butyllithium was added slowly and dropwise to the reaction system, followed by 9.38 mL (3.0 eq.) of N,N-dimethylacetamide (DMAc). The reaction mixture was stirred and gradually warmed to 20 °C. Upon completion of the reaction, the reaction was quenched by the addition of saturated aqueous ammonium chloride, followed by extraction and liquid-liquid separation. The organic phase was purified by silica gel column chromatography to afford the target product 2-acetyl-5-bromopyridine (Compound I-1-2) 6.74 g in 100% yield as a white solid.
References
[1] Patent: JP2016/56276, 2016, A. Location in patent: Paragraph 0111; 0112
[2] Tetrahedron, 2008, vol. 64, # 17, p. 3794 - 3801
[3] Dalton Transactions, 2011, vol. 40, # 29, p. 7534 - 7540
[4] Journal of the American Chemical Society, 2016, vol. 138, # 38, p. 12643 - 12647
[5] Patent: WO2015/27021, 2015, A1. Location in patent: Page/Page column 78
1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16514 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2161 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
View Lastest Price from 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-10-13 | 1-(5-Bromopyridin-2-yl)ethanone
214701-49-2
|
US $1.10-9.90 / KG | 1KG | 99% min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
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2021-08-19 | 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
214701-49-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
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2020-02-01 | 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
214701-49-2
|
US $3.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
-

- 1-(5-Bromopyridin-2-yl)ethanone
214701-49-2
- US $1.10-9.90 / KG
- 99% min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
214701-49-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-

- 1-(5-BROMO-PYRIDIN-2-YL)-ETHANONE
214701-49-2
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
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