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2-(4-Fluorophenyl)-thiophene

2-(4-Fluorophenyl)-thiophene Structure
2-(4-Fluorophenyl)-thiophene structure
CAS No.
58861-48-6
Chemical Name:
2-(4-Fluorophenyl)-thiophene
Synonyms
2-(4-FL;AKOS BAR-1344;Canagliflozin INT2;IFLAB-BB F2108-0130;Impurity of caglitazin;FLUOROPHENYL)THIOPHENE;Cagliflozin Impurity 14;2-(4-Fluorphenyl)thiophen;2-(4-fluorophenyl)thiophen;Canagliflozin intermediate
CBNumber:
CB1294813
Molecular Formula:
C10H7FS
Molecular Weight:
178.23
MDL Number:
MFCD06802535
MOL File:
58861-48-6.mol
Last updated:2024-04-16 14:59:45
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2-(4-Fluorophenyl)-thiophene Properties

Melting point 51.0 to 55.0 °C
Boiling point 252.3±15.0 °C(Predicted)
Density 1.200±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility soluble in Methanol
form powder to crystal
color Light orange to Yellow to Green
InChI InChI=1S/C10H7FS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H
InChIKey PURJRGMZIKXDMW-UHFFFAOYSA-N
SMILES C1(C2=CC=C(F)C=C2)SC=CC=1
CAS DataBase Reference 58861-48-6
FDA UNII 72TG563TMB

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
HS Code  2934999090

2-(4-Fluorophenyl)-thiophene price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0724 2-(4-Fluorophenyl)thiophene >95.0%(GC) 58861-48-6 1g $50 2024-03-01 Buy
TCI Chemical F0724 2-(4-Fluorophenyl)thiophene >95.0%(GC) 58861-48-6 5g $153 2024-03-01 Buy
TRC F591560 2-(4-Fluorophenyl)-thiophene 58861-48-6 5g $1295 2021-12-16 Buy
Matrix Scientific 090403 2-(4-Fluorophenyl)thiophene 95+% 58861-48-6 5g $1418 2021-12-16 Buy
American Custom Chemicals Corporation HCH0010377 2-(4-FLUORO-PHENYL)-THIOPHENE 95.00% 58861-48-6 20G $1903 2021-12-16 Buy
Product number Packaging Price Buy
F0724 1g $50 Buy
F0724 5g $153 Buy
F591560 5g $1295 Buy
090403 5g $1418 Buy
HCH0010377 20G $1903 Buy

2-(4-Fluorophenyl)-thiophene Chemical Properties,Uses,Production

Chemical Properties

white solid

Uses

2-(4-Fluorophenyl)-thiophene can be used to prepare Canagliflozin (C175190) as sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor for treatment of type 2 diabetes mellitus.

Synthesis

4-fluorobenzoic boric acid and 2-bromothiophene, Pd catalyst are added in organic solvent and dissolves, obtain material 3, wherein: 4-fluorine Phenylboric acid molar concentration in organic solvent is 0.5mol/L～2mol/L, and 4-fluorobenzoic boric acid with the mol ratio of 2-bromothiophene is 1:1.0～1:1.5,4-fluorobenzoic boric acid is 1:0.005～1:0.1 with the mol ratio of catalyst；Using material 3 with as material 4 Inorganic base aqueous solution carries out pre-incubation respectively to being 1:1.0～1 according to the mol ratio of 4-fluorobenzoic boric acid Yu alkali after reaction temperature: The mode of 3.0 mixes, and reacts under conditions of 50 ℃～80 ℃, then carries out post processing and obtains 2-(4-fluorophenyl) Thiophene.

2-(4-Fluorophenyl)-thiophene synthesis

1003-09-4
1765-93-1
58861-48-6
Synthesis of 2-(4-Fluorophenyl)-thiophene from 2-Bromothiophene and 4-Fluorobenzeneboronic acid

2-(4-Fluorophenyl)-thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

5-(4-Fluorophenyl)thiophene-2-carboxylic acid (5-broMo-2-Methylphenyl)(5-(4-fluorophenyl)thiophen-2-yl)Methanone

2-(4-Fluorophenyl)-thiophene Suppliers

Global( 365)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
+86-18616643091 +86-18616643091 info@rochipharma.com China 246 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 811 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 341 58
Supplier Advantage
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Hi-Tech Chemistry Corp 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Anqing Chico Pharmaceutical Co., Ltd. 		58

View Lastest Price from 2-(4-Fluorophenyl)-thiophene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-Fluorophenyl)-thiophene pictures 2024-04-16 2-(4-Fluorophenyl)-thiophene
58861-48-6
 US $5.00-0.10 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-(p-Fluorophenyl)thiophene pictures 2024-01-02 2-(p-Fluorophenyl)thiophene
58861-48-6
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
2-(4-FLUOROPHENYL)THIOPHENE pictures 2023-09-15 2-(4-FLUOROPHENYL)THIOPHENE
58861-48-6
 US $0.00 / kg 1kg 99% 20tons Hebei Yanxi Chemical Co., Ltd.

58861-48-6( 2-(4-Fluorophenyl)-thiophene)Related Search:

3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE METHYL 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLATE DUP-697 Ethyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate ,98% 3-AMINO-2-CYANO-5-(4-FLUOROPHENYL)THIOPHENE,3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBONITRILE
3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE 5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLI& 6-(4-FLUOROPHENYL)-3,4-DIHYDROTHIENO[3,2-D]-PYRIMIDIN-4-ONE METHYL 5-(4-FLUOROPHENYL)-2-THIOPHENECARBOXYLATE 4-CHLORO-6-(4-FLUOROPHENYL)THIENO[3,2-D]PYRIMIDINE
Methyl 2-[(chloroacetyl)amino]-4-(4-fluorophenyl)-thiophene-3-carboxylate 2-Amino-N-(2-fluorophenyl)thiophene-3-carboxamide Isopropyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate N-(5-amino-2-fluorophenyl)thiophene-2-sulfonamide 5-(3-fluorophenyl)thiophene-2-carboxylic acid
methyl 2-[(cyanoacetyl)amino]-4-(4-fluorophenyl)thiophene-3-carboxylate ethyl 2-amino-4-(3-fluorophenyl)thiophene-3-carboxylate N-(3-amino-4-fluorophenyl)thiophene-2-carboxamide

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IFLAB-BB F2108-0130 2-(4-FLUOROPHENYL)THIOPHENE AKOS BAR-1344 Thiophene, 2-(4-fluorophenyl)- Canagliflozin Intermediate I Canagliflozin INT2 2-(4-fluorophenyl)thiophen Canagliflozin Related Impurity 14 Cagliflozin Impurity 14 2-(4-Fluorophenyl)thiophene> 2-(4-FL Impurity of caglitazin 2-(4-FLUOROPHENYL)THIOPHENE 58861-48-6 2-(4-FLUOROPHENYL)THIOPHENE ISO 9001：2015 REACH Canagliflozin intermediate 2-(4-Fluorphenyl)thiophen 2-(p-Fluorophenyl)thiophene FLUOROPHENYL)THIOPHENE 58861-48-6 58861-48-6