ChemicalBook >> CAS DataBase List >>Hydroxypioglitazone
Hydroxypioglitazone
- CAS No.
- 146062-44-4
- Chemical Name:
- Hydroxypioglitazone
- Synonyms
- Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV) ;Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
- CBNumber:
- CB1299313
- Molecular Formula:
- C19H20N2O4S
- Molecular Weight:
- 372.44
- MDL Number:
- MFCD00916074
- MOL File:
- 146062-44-4.mol
- MSDS File:
- SDS
Last updated:2023-07-12 16:47:46
| Melting point | 157-1580C |
|---|---|
| Boiling point | 627.6±55.0 °C(Predicted) |
| Density | 1.325±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
| pka | 6.35±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| CAS DataBase Reference | 146062-44-4 |
| FDA UNII | K824X25AYA |
Hydroxypioglitazone price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28043 | Hydroxy Pioglitazone | 146062-44-4 | 1mg | $275 | 2024-03-01 | Buy |
| Cayman Chemical | 28043 | Hydroxy Pioglitazone | 146062-44-4 | 5mg | $820 | 2024-03-01 | Buy |
| Usbiological | 293691 | Hydroxy pioglitazone | 146062-44-4 | 1mg | $827 | 2021-12-16 | Buy |
| Usbiological | 293692 | Hydroxy pioglitazone | 146062-44-4 | 1mg | $891 | 2021-12-16 | Buy |
| TRC | H952075 | HydroxyPioglitazone(M-IV) | 146062-44-4 | 10mg | $1450 | 2021-12-16 | Buy |
Hydroxypioglitazone Chemical Properties,Uses,Production
Description
Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (Ki = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC50 = 2.1 μM).
Chemical Properties
Off-White Solid
Uses
A metabolite of Pioglitazone (P471000).
Definition
ChEBI: Hydroxypioglitazone is a member of the class of thiazolidenediones that is the hydroxy derivative of pioglitazone. It has a role as a human xenobiotic metabolite. It is a member of thiazolidinediones, a member of pyridines and an aromatic ether. It is functionally related to a pioglitazone.
Hydroxypioglitazone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
View Lastest Price from Hydroxypioglitazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Hydroxypioglitazone
146062-44-4
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- Hydroxypioglitazone
146062-44-4
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
146062-44-4(Hydroxypioglitazone)Related Search:
Pioglitazone hydrochloride
a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester
Pioglitazone Aldehyde Impurity
5-(4-Fluorobenzyl)-2,4-thiazolidinedione
4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde
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HYDROXYPIOGLITAZONE
Hydroxy Pioglitazone (M-IV)
5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
Pioglitazone, hydroxy M-IV
Pioglitazone Impurity 18
Hydroxy Pioglitazone Solution, 100ppm
Pioglitazone M4 Metabolite
Leriglitazone
Pioglitazone Impurity 4
2,4-Thiazolidinedione, 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-
Hydroxypioglitazone M4
146062-44-4
Sulfur & Selenium Compounds
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals