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methyl 3-bromo-5-fluoro-2-methylbenzoate

CAS No.
1187318-53-1
Chemical Name:
methyl 3-bromo-5-fluoro-2-methylbenzoate
Synonyms
methyl 3-bromo-5-fluoro-2-methylbenzoate;3-BROMO-5-FLUORO-2-METHYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-bromo-5-fluoro-2-methyl-, methyl ester
CBNumber:
CB13033143
Molecular Formula:
C9H8BrFO2
Molecular Weight:
247.06
MDL Number:
MFCD19440363
MOL File:
1187318-53-1.mol
Last updated:2025-07-24 18:13:43

methyl 3-bromo-5-fluoro-2-methylbenzoate Properties

Boiling point 262.9±40.0 °C(Predicted)
Density 1.506±0.06 g/cm3(Predicted)
storage temp. 2-8°C
Appearance Colorless to light yellow Solid-Liquid Mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2916399090

methyl 3-bromo-5-fluoro-2-methylbenzoate price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B679560 3-Bromo-5-fluoro-2-methyl-benzoicAcidMethylEster 1187318-53-1 500mg $330 2021-12-16 Buy
Apolloscientific PC510281 Methyl 3-Bromo-5-fluoro-2-methylbenzoate 1187318-53-1 5g $1122 2021-12-16 Buy
ChemScene CS-0061182 Methyl3-bromo-5-fluoro-2-methylbenzoate 1187318-53-1 5g $597 2021-12-16 Buy
ChemScene CS-0061182 Methyl3-bromo-5-fluoro-2-methylbenzoate 1187318-53-1 100mg $54 2021-12-16 Buy
ChemScene CS-0061182 Methyl3-bromo-5-fluoro-2-methylbenzoate 1187318-53-1 250mg $94 2021-12-16 Buy
Product number Packaging Price Buy
B679560 500mg $330 Buy
PC510281 5g $1122 Buy
CS-0061182 5g $597 Buy
CS-0061182 100mg $54 Buy
CS-0061182 250mg $94 Buy

methyl 3-bromo-5-fluoro-2-methylbenzoate Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

3-bromo-5-fluoro-2-methylbenzoic acid

1187318-52-0

methyl 3-bromo-5-fluoro-2-methylbenzoate

1187318-53-1

At room temperature, 2-methyl-3-bromo-5-fluorobenzoic acid (4.2 g, crude) was dissolved in methanol (16 mL) and thionyl chloride (2.5 mL) was added slowly. The reaction mixture was heated to 70 °C with continuous stirring for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed under reduced pressure by rotary evaporator to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (50:1, v/v) to afford methyl 3-bromo-5-fluoro-2-methylbenzoate (2.3 g, 51% yield) as a yellow oil.

References

[1] Patent: WO2017/201069, 2017, A1. Location in patent: Paragraph 0516

175278-29-2
1187318-53-1
Synthesis of methyl 3-bromo-5-fluoro-2-methylbenzoate from Methyl 5-fluoro-2-methylbenzoate

methyl 3-bromo-5-fluoro-2-methylbenzoate Preparation Products And Raw materials

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methyl 3-bromo-5-fluoro-2-methylbenzoate Spectrum

methyl 3-bromo-5-fluoro-2-methylbenzoate 3-BROMO-5-FLUORO-2-METHYL-BENZOIC ACID METHYL ESTER Benzoic acid, 3-bromo-5-fluoro-2-methyl-, methyl ester 1187318-53-1