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Nonapeptide-1

Nonapeptide-1 structure

CAS No.: 158563-45-2

Chemical Name:: Nonapeptide-1

Synonyms: melanostatine;Melanostatine-5;Melitan;Neptide-1;Jiupeptide-1;NONAPEPTIDE-1;Metanostatine-5;Melitane / Nonapeptide-1;hexapeptide-2/Dermostatyl;4-Hydroxypyridine 626-64-2

CBNumber:: CB13052001

Molecular Formula:: C61H87N15O9S

Molecular Weight:: 1206.5

MDL Number:: MFCD00672435

MOL File:: 158563-45-2.mol

Last updated:2024-04-18 17:30:06

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Nonapeptide-1 Properties

Density	1.38±0.1 g/cm3(Predicted)
solubility	soluble in water(≥0.1g/ml)
pka	13.32±0.46(Predicted)
color	white or off-white powder
InChIKey	KNFLNGRLKALWRF-LDXSYGEZSA-N
FDA UNII	64W45420K5

Nonapeptide-1 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biorbyt Ltd	orb372551	Melanostatine-5 > 95%	158563-45-2	1mg	$287.3	2021-12-16	Buy
Biorbyt Ltd	orb372551	Melanostatine-5 > 95%	158563-45-2	5mg	$552.5	2021-12-16	Buy
Biorbyt Ltd	orb372551	Melanostatine-5 > 95%	158563-45-2	10mg	$708.9	2021-12-16	Buy
Chemenu	CM100718	Nonapeptide-1 97%	158563-45-2	1g	$355	2021-12-16	Buy
Crysdot	CD22004464	H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 97%	158563-45-2	1g	$376	2021-12-16	Buy

Product number	Packaging	Price	Buy
orb372551	1mg	$287.3	Buy
orb372551	5mg	$552.5	Buy
orb372551	10mg	$708.9	Buy
CM100718	1g	$355	Buy
CD22004464	1g	$376	Buy

Nonapeptide-1 Chemical Properties,Uses,Production

Description

Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.

Uses

A skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.

Application

skin radiance, skin Lightening-whitening, anti-dark spot

Definition

Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.

benefits

Nonapeptide-1inhibits melanin production originally induced bya-MSH.Whitening, spot-removing as well as preventing hyperpigmentation.Its recommended dosage in skin care products is 0.5~3%.

Biological Functions

1. Inhibit melanin synthesis by interfering with the action of tyrosinase in melanocytes. Reduce hyperpigmentation and lighten darker areas that have been damaged by the sun and certain diseases.2. Interfer with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure.3. Nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin in fungi.4. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43%

Biotechnological Applications

Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1].

Side effects

May cause drowsiness, dizziness, hypotension, or a headache as side-effects when using Nonapeptide-1 Topical medicine. Patients not drink alcohol with medicines as alcohol intensifies drowsiness side-effects.

storage

Common storage 2-8℃, long time storage -20℃.

Nonapeptide-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Nonapeptide-1 Suppliers

Global( 257)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Getian Industrial Co., LTD	+undefined15373193816	mike@ge-tian.com	China	272	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
Xinxiang Hongqi District Houyuan Trading Co.,Ltd	+86-0373-3695376 +86-13937349994	HYJM@houyuanjm.com	China	300	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Hantai Biomedical Group Co. LTD	+8618819265912	id002@cnhantide.com	China	37	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58
Wuhan Marco Pharmaceutical Technology Co., Ltd.	+86-86-18572802410 +8618572802410	sales@marcopht.com	China	55	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6711	58

Supplier	Advantage
Shanghai Getian Industrial Co., LTD	58
Cellmano Biotech Limited	58
Xinxiang Hongqi District Houyuan Trading Co.,Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Hantai Biomedical Group Co. LTD	58
GIHI CHEMICALS CO.,LIMITED	58
Wuhan Marco Pharmaceutical Technology Co., Ltd.	58
Hebei Mojin Biotechnology Co., Ltd	58
Shanghai UCHEM Inc.	58

View Lastest Price from Nonapeptide-1 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	Nonapeptide-1 158563-45-2	US $0.00 / g	10g	99%	10000g	Shaanxi TNJONE Pharmaceutical Co., Ltd
2024-04-19	Nonapeptide-1 158563-45-2	US $10.00 / mg	15mg	0.98	1kg	Shanghai UCHEM Inc.
2024-04-19	Nonapeptide-1 158563-45-2	US $30.00 / kg	1kg	99%	100kg	Wuhan Cell Pharmaceutical Co., Ltd

Nonapeptide-1
158563-45-2
US $0.00 / g
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Nonapeptide-1
158563-45-2
US $10.00 / mg
0.98
Shanghai UCHEM Inc.

Nonapeptide-1
158563-45-2
US $30.00 / kg
99%
Wuhan Cell Pharmaceutical Co., Ltd

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1of4

L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide Melanostatine-5(nonpeptide-1) Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH₂ Melitane / Nonapeptide-1 Melanostatine-5, Nonapeptide-1 NONAPEPTIDE-1 Nonapeptide-1, Melanostatine-5, Melanostatine Melitan Nonapeptide-1/Melitane/Melanostatine Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val- L-Valinamide, L-methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl- Cosmetics peptide Nonapeptide-1 powder Nonapeptide-1(Melanostatine-5) Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 USP/EP/BP hexapeptide-2/Dermostatyl superior quality Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 CAS 158563-45-2 CAS 158563-45-2 Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2 Melanostatine-5 melanostatine Metanostatine-5 4-Hydroxypyridine 626-64-2 (Met?,Pro?,D-Phe?,D-Trp?,Phe1?)-α-MSH (5-13) (Met?,Pro?,D-Phe?,D-Trp?,Phe??)-α-MSH (5-13) Jiupeptide-1 Neptide-1 158563-45-2 951-78-9 C61H87N15O9S 158563-45-2