ChemicalBook >> CAS DataBase List >>Mal-PEG2-acid
Mal-PEG2-acid
- CAS No.
- 1374666-32-6
- Chemical Name:
- Mal-PEG2-acid
- Synonyms
- Mal-PEG2-acid;Mal-PEG2-C2-COOH;Mal-NH-PEG2-acid;Mal-PEG2-CH2CH2COOH;Maleimide-PEG2-CH2CH2COOH;α-Maleimidyl-ω-propionyloxy poly(ethylene glycol);3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid;3-[2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic acid;3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
- CBNumber:
- CB13062529
- Molecular Formula:
- C11H15NO6
- Molecular Weight:
- 257.24
- MDL Number:
- MFCD23726620
- MOL File:
- 1374666-32-6.mol
Last updated:2024-03-27 13:09:27
| Boiling point | 455.7±35.0 °C(Predicted) |
|---|---|
| Density | 1.329±0.06 g/cm3(Predicted) |
| pka | 4.27±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| CAS DataBase Reference | 1374666-32-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P271-P261-P280 | |||||||||
| HS Code | 2942000090 | |||||||||
| NFPA 704 |
|
Mal-PEG2-acid price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M3203 | Mal-PEG2-acid | 1374666-32-6 | 250MG | $93 | 2024-03-01 | Buy |
| TCI Chemical | M3203 | Mal-PEG2-acid | 1374666-32-6 | 1G | $294 | 2024-03-01 | Buy |
| TRC | M158208 | Mal-PEG2-acid | 1374666-32-6 | 5mg | $65 | 2021-12-16 | Buy |
| TRC | M158208 | Mal-PEG2-acid | 1374666-32-6 | 10mg | $90 | 2021-12-16 | Buy |
| TRC | M158208 | Mal-PEG2-acid | 1374666-32-6 | 50mg | $330 | 2021-12-16 | Buy |
Mal-PEG2-acid Chemical Properties,Uses,Production
Description
Mal-PEG2-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Mal-PEG2-acid is a non-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It can bind to Tubulysin (HY-128914) and its cytotoxic derivatives activity. It can also be used as a PROTAC linker for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Non-cleavable < span> | PEGs
|
Mal-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18456 | 58 |
View Lastest Price from Mal-PEG2-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-27 | Mal-PEG2-acid
1374666-32-6
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
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- Mal-PEG2-acid
1374666-32-6
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
Mal-PEG2-acid
Maleimide-PEG2-CH2CH2COOH
Mal-PEG2-CH2CH2COOH
Mal-NH-PEG2-acid
3-[2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic acid
α-Maleimidyl-ω-propionyloxy poly(ethylene glycol)
Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid
Mal-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
Mal-PEG2-C2-COOH
3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid
1374666-32-6
peg