Ethopabate
- CAS No.
- 59-06-3
- Chemical Name:
- Ethopabate
- Synonyms
- METHYL 4-ACETAMIDO-2-ETHOXYBENZOATE;4-Acetamido-2-ethoxybenzoic acid, methyl ester;Ethopatate;ETHOPABATE;Ethytpatate;Ethyl pabate;Isovaleraldehvde;Ethopabate (125 mg);Ethopabate, Vetranal;Ethopabate (1262801)
- CBNumber:
- CB1307306
- Molecular Formula:
- C12H15NO4
- Molecular Weight:
- 237.25
- MDL Number:
- MFCD00075809
- MOL File:
- 59-06-3.mol
- MSDS File:
- SDS
| Melting point | 148-151 °C |
|---|---|
| Boiling point | 426.1±35.0 °C(Predicted) |
| Density | 1.180±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: 50 mg/mL (210.75 mM) |
| form | A solid |
| pka | 14.12±0.70(Predicted) |
| Merck | 13,3781 |
| InChI | InChI=1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14) |
| InChIKey | GOVWOKSKFSBNGD-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(NC(C)=O)C=C1OCC |
| FDA 21 CFR | 556.260 |
| CAS DataBase Reference | 59-06-3(CAS DataBase Reference) |
| FDA UNII | F4X3L6068O |
| EPA Substance Registry System | Ethopabate (59-06-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924296000 | |||||||||
| NFPA 704 |
|
Ethopabate price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1262801 | Ethopabate United States Pharmacopeia (USP) Reference Standard | 59-06-3 | 125mg | $358 | 2024-03-01 | Buy |
| Usbiological | 011457 | Ethopabate | 59-06-3 | 250mg | $418 | 2021-12-16 | Buy |
| TRC | E890800 | Ethopabate | 59-06-3 | 250mg | $145 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | APN0000389 | METHYL-4-ACETAMIDO-2-ETHOXYBENZOATE 95.00% | 59-06-3 | 1G | $329.7 | 2021-12-16 | Buy |
| ChemScene | CS-8028 | Ethopabate 99.42% | 59-06-3 | 500mg | $96 | 2021-12-16 | Buy |
Ethopabate Chemical Properties,Uses,Production
Description
Ethopabate is a veterinary drug belonging to the class of antibiotics which contains an arylamide with a phenyl ring, a monocyclic aromatic hydrocarbon, and is a very safe drug used for the prophylaxis and treatment of coccidiosis in chickens. It has anticoccidial activity, especially against the intestinal form, and lacks activity against E. tenella of the cecum worm. The drug is a competitor of PABA, which is absorbed by the parasite and interferes with folate synthesis. It has good activity against E. acervulina and some strains of E. maxima and E. brunette. It is used only in combination with amprolium, first at a concentration of 4 ppm and later at a concentration of 40 ppm.This drug reaches peak activity on day 4 of the cycle.
Chemical Properties
White to Off-White Solid
Uses
A supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens.
Uses
antidepressant
Definition
ChEBI: Ethopabate is an amidobenzoic acid.
Clinical Use
Ethopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide.
Molecular Interactions
Ethopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones.
Ethopabate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 893 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Ethopabate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-11 | Ethopabate
59-06-3
|
US $0.00 / kg | 1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-03-12 | Ethopabate
59-06-3
|
US $0.00 / kg | 1kg | 98% HPLC | 100kg | shandong perfect biotechnology co.ltd | |
 |
2023-09-26 | Ethopabate
59-06-3
|
US $0.00 / kg | 1kg | 98.00% | 20tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Ethopabate
59-06-3
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Ethopabate
59-06-3
- US $0.00 / kg
- 98% HPLC
- shandong perfect biotechnology co.ltd
-
- Ethopabate
59-06-3
- US $0.00 / kg
- 98.00%
- Hebei Yanxi Chemical Co., Ltd.