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DCEBIO

CAS No.
60563-36-2
Chemical Name:
DCEBIO
Synonyms
DCEBIO;Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor;5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE;2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-
CBNumber:
CB1308237
Molecular Formula:
C9H8Cl2N2O
Molecular Weight:
231.08
MDL Number:
MFCD04040030
MOL File:
60563-36-2.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

DCEBIO Properties

Melting point 205-207 °C(Solv: ethyl acetate (141-78-6))
Density 1.412±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: >10mg/mL
form solid
pka 10.28±0.30(Predicted)
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

DCEBIO price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D9190 DCEBIO ≥98% (HPLC), solid 60563-36-2 5mg $200 2024-03-01 Buy
Sigma-Aldrich D9190 DCEBIO ≥98% (HPLC), solid 60563-36-2 25mg $770 2023-06-20 Buy
Cayman Chemical 29426 DCEBIO 60563-36-2 5mg $68 2024-03-01 Buy
Cayman Chemical 29426 DCEBIO 60563-36-2 10mg $116 2024-03-01 Buy
Cayman Chemical 29426 DCEBIO 60563-36-2 25mg $268 2024-03-01 Buy
Product number Packaging Price Buy
D9190 5mg $200 Buy
D9190 25mg $770 Buy
29426 5mg $68 Buy
29426 10mg $116 Buy
29426 25mg $268 Buy

DCEBIO Chemical Properties,Uses,Production

Description

DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl- secretion in T84 colonic cells. DCEBIO stimulates Cl- secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl- conductance. 

Uses

DCEBIO is a small Ca2+sensitive K+ channel (SKCa) agonist. It also stimulate nitric oxide (NO) synthesis and vasodilation in resistance arteries.

Definition

ChEBI: DCEBIO is a dichlorobenzene.

Biological Activity

Stimulates Cl - secretion via activation of hIK1 K + channels and the activation of an apical Cl - conductance. More potent than its analog 1-EBIO (1-Ethyl-2-benzimidazolinone ).

storage

Store at RT

DCEBIO Preparation Products And Raw materials

Raw materials

Preparation Products

DCEBIO Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
PharmOrgSyn Laboratories Co., Ltd.
+86-021-38228826 +86-13916602830 sales@pharmorgsyn.cn China 140 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4271 65
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9900 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9442 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9901 58

DCEBIO Spectrum

DCEBIO 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE 5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE 5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE 2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro- Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor 60563-36-2 C9H8N2OCl2 Chloride Channel Modulators Voltage-gated Ion Channels Monovalent Ion Channels Ion Channels Cell Biology Cell Signaling and Neuroscience BioChemical Potassium channel