ANTI-AMYLOID, BETA
- CAS No.
- 879564-86-0
- Chemical Name:
- ANTI-AMYLOID, BETA
- Synonyms
- Anti-PN2;Anti-AAA;Anti-AD1;Anti-APPI;Anti-CVAP;Anti-ABPP;ANTI-ABETA;Rhodblock 3;Clone BAM91;Anti-CTFgamma
- CBNumber:
- CB1309375
- Molecular Formula:
- C11H10ClNO2
- Molecular Weight:
- 223.66
- MDL Number:
- MFCD06771404
- MOL File:
- 879564-86-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
ANTI-AMYLOID, BETA price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2100135 | Anti-APP (ab2) antibody produced in rabbit affinity isolated antibody | 879564-86-0 | 100μL | $478 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB4200536 | Anti-APP (N-terminal region) antibody produced in rabbit IgG fraction of antiserum | 200μL | $489 | 2023-06-20 | Buy | |
| Sigma-Aldrich | R1533 | Rhodblock 3 ≥98% (HPLC) | 879564-86-0 | 5mg | $137 | 2022-05-15 | Buy |
| Sigma-Aldrich | R1533 | Rhodblock 3 ≥98% (HPLC) | 879564-86-0 | 25mg | $544 | 2022-05-15 | Buy |
ANTI-AMYLOID, BETA Chemical Properties,Uses,Production
Uses
The antibody is useful in immunohistochemistry, immunoblotting, ELISA, and competitive ELISA. Also, this antibody has been used to neutralize Aβ assemblies in brains of transgenic mice expressing a mutant form of amyloid precursor protein, and for in vivo deep tissue imaging using near-IR optical spectrum.
General Description
The antibody reacts specifically with β-amyloid protein. The epitope recognized by the antibody resides within amino acids 1-12 of the β-amyloid protein. It specifically stains amyloid plaques within the cortex and amyloid deposits in blood vessels using formic acid-treated, formalin-fixed, paraffin-embedded, and Methacarn-fixed sections of human Alzheimer′s disease (AD) brain tissue.
Biochem/physiol Actions
β-amyloid gene acts as the substrate of insulin-degrading enzyme (IDE). It plays a major role in the pathogenesis of Alzheimer′s disease (AD) and type 2 diabetes mellitus (DM2).
ANTI-AMYLOID, BETA Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-AMYLOID, BETA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Sigma-Aldrich | 80 |
| Energy Chemical | 58 |
| TargetMol Chemicals Inc. | 58 |