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ChemicalBook >> CAS DataBase List >>1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Structure
1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid structure
CAS No.
1144504-35-7
Chemical Name:
1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid
Synonyms
PQCA;1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid;4H-Quinolizine-3-carboxylic acid, 1-[[4-cyano-4-(2-pyridinyl)-1-piperidinyl]methyl]-4-oxo-
CBNumber:
CB13100995
Molecular Formula:
C22H20N4O3
Molecular Weight:
388.42
MDL Number:
MFCD26403374
MOL File:
1144504-35-7.mol
Last updated:2023-05-21 10:59:17
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1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Properties

Boiling point 708.5±60.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 10 mg/mL (25.75 mM; ultrasonic and warming and heat to 80°C)
pka 1.83±0.20(Predicted)

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0065722 PQCA 99.78% 1144504-35-7 5mg $400 2021-12-16 Buy
ChemScene CS-0065722 PQCA 99.78% 1144504-35-7 10mg $680 2021-12-16 Buy
ChemScene CS-0065722 PQCA 99.78% 1144504-35-7 25mg $1350 2021-12-16 Buy
ChemScene CS-0065722 PQCA 99.78% 1144504-35-7 50mg $2200 2021-12-16 Buy
ChemScene CS-0065722 PQCA 99.78% 1144504-35-7 100mg $3400 2021-12-16 Buy
Product number Packaging Price Buy
CS-0065722 5mg $400 Buy
CS-0065722 10mg $680 Buy
CS-0065722 25mg $1350 Buy
CS-0065722 50mg $2200 Buy
CS-0065722 100mg $3400 Buy

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Chemical Properties,Uses,Production

Uses

PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA is a novel M1 muscarinic potentiator that improves cognition without adverse effects compared to donepezil and xanomeline in rhesus monkey.

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24023 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
TargetMol Chemicals Inc. 58
1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid PQCA 4H-Quinolizine-3-carboxylic acid, 1-[[4-cyano-4-(2-pyridinyl)-1-piperidinyl]methyl]-4-oxo- 1144504-35-7