Acebilustat
- CAS No.
- 943764-99-6
- Chemical Name:
- Acebilustat
- Synonyms
- ZK-322;ZK 322;CS-2501;CTX-4430;Acebilustat;ZK 322;ZK-322;Acebilustat(ZK322);Acebilustat,CTX-4430;Acebilustat USP/EP/BP;Acebilustat,Aminopeptidase,Inhibitor,inhibit,CTX 4430,CTX4430
- CBNumber:
- CB13155056
- Molecular Formula:
- C29H27N3O4
- Molecular Weight:
- 481.54
- MDL Number:
- MFCD30496703
- MOL File:
- 943764-99-6.mol
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
|---|---|
| solubility | Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble |
| form | A crystalline solid |
| CAS DataBase Reference | 943764-99-6 |
| FDA UNII | J64RI4D29U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| NFPA 704 |
|
Acebilustat price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Ambeed | A639379 | Acebilustat 99% | 943764-99-6 | 5mg | $373 | 2021-12-16 | Buy |
| DC Chemicals | DC9986 | Acebilustat(ZK322) >98% | 943764-99-6 | 250mg | $1200 | 2021-12-16 | Buy |
| DC Chemicals | DC9986 | Acebilustat(ZK322) >98% | 943764-99-6 | 1g | $2500 | 2021-12-16 | Buy |
Acebilustat Chemical Properties,Uses,Production
Description
Acebilustat (also known as CTX-4430) is a new once-daily oral anti-inflammatory drug in development for treatment of cystic fibrosis (CF) and other diseases. It is an inhibitor of leukotriene A4 hydrolase, which is responsible for the production of leukotriene B4 (LTB4). The later is a molecule that leads to inflammation. Therefore, Acebilustat can treat inflammation through suppressing the production of leukotriene B4.
References
https://www.cff.org/Trials/Pipeline/details/108/CTX-4430
Springman, E., et al. "127 Pharmacokinetic and pharmacodynamic profile of CTX-4430 in two phase 1 studies." Journal of Cystic Fibrosis14(2015):S90-S90.
Springman, E., et al. "126 A phase 1 clinical study of CTX-4430 in cystic fibrosis patients." Journal of Cystic Fibrosis 14(2015):S90-S90.
Elborn, J. S., et al. "Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction." Clinical & Translational Science 10.1(2017):20-27.
Acebilustat Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
View Lastest Price from Acebilustat manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-10-16 | Acebilustat
943764-99-6
|
US $0.00 / kg | 1kg | 0.99 | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2021-08-18 | Acebilustat USP/EP/BP
943764-99-6
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-
- Acebilustat
943764-99-6
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Acebilustat USP/EP/BP
943764-99-6
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited