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Diclazuril

CAS No.
101831-37-2
Chemical Name:
Diclazuril
Synonyms
Qiujia;Nuoqiu;Vecoxan;R-64433;CLINACOX;clinazox;iclazuril;DICLAZUTIL;DICLAZURIL;To g beads
CBNumber:
CB1317293
Molecular Formula:
C17H9Cl3N4O2
Molecular Weight:
407.64
MDL Number:
MFCD00867203
MOL File:
101831-37-2.mol
MSDS File:
SDS
Last updated:2024-03-26 17:16:27

Diclazuril Properties

Melting point 290.5°
Density 1.56±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL
pka 5.89±0.20(Predicted)
color White to Light yellow to Light orange
Merck 14,3080
InChI InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)
InChIKey ZSZFUDFOPOMEET-UHFFFAOYSA-N
SMILES C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O
LogP 2.439 (est)
CAS DataBase Reference 101831-37-2(CAS DataBase Reference)
FDA 21 CFR 556.185; 558.205; 558.4
FDA UNII K110K1B1VE

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361d-H373
Precautionary statements  P202-P260-P280-P308+P313-P405-P501
Safety Statements  24/25
WGK Germany  2
RTECS  CY1697600
HS Code  29336990

Diclazuril price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34057 Diclazuril VETRANAL?, analytical standard 101831-37-2 100mg $113 2024-03-01 Buy
Sigma-Aldrich 1188560 Diclazuril United States Pharmacopeia (USP) Reference Standard 101831-37-2 200mg $436 2024-03-01 Buy
TCI Chemical D5457 Diclazuril >98.0%(HPLC)(T) 101831-37-2 1g $53 2024-03-01 Buy
TCI Chemical D5457 Diclazuril >98.0%(HPLC)(T) 101831-37-2 5g $262 2024-03-01 Buy
Cayman Chemical 27047 Diclazuril 101831-37-2 5g $68 2024-03-01 Buy
Product number Packaging Price Buy
34057 100mg $113 Buy
1188560 200mg $436 Buy
D5457 1g $53 Buy
D5457 5g $262 Buy
27047 5g $68 Buy

Diclazuril Chemical Properties,Uses,Production

Description

Diclazuril (molecular formula: C17H9Cl3N4O2, Trade name: Vecoxan) belongs to a kind of coccidiostat and potent antiprotozoal agents. It is mainly used for the treatment, control, prevention and improvements of Coccidal infections. It alleviates the symptoms of the patients by interrupting the life cycle of the parasites. It induces the morphological changes and attenuates the mitochondrial transmembrane potential in meroites. It can prevent congenital toxoplasmosis and have anticoccidial effects in vivo. It is active through oral administration.  

References

http://www.tabletwise.com/medicine/diclazuril
https://en.wikipedia.org/wiki/Diclazuril
http://www.abcam.com/diclazuril-ab143604.html

Chemical Properties

Light yellow or off-white powder, almost insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methylformamide (DMF), dimethylsulfone (DMSO), tetrahydrofuran (THF).

Uses

Diclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits.

Definition

ChEBI: 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile is a nitrile.

Application

Diclazuril is a less toxic, orally administered triazine antiprotozoal. It is widely used in veterinary medicine as a feed additive and veterinary drug. It is registered for oral use in broilers and lambs. Its use in cats (one dose of 25 mg/kg BW) is off-label only. It may be used clinically for the treatment of bovine protozoa. It is also used for the treatment of equine protozoan spinal cord encephalitis (EPM) caused by neuronal sarcocysts.

Veterinary Drugs and Treatments

Diclazuril is a coccidiostat. It is indicated for the treatment of equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona and as a coccidiostat in broiler chickens. Diclazuril could potentially be useful in treating coccidiosis, Neospora caninum and Toxoplasma infections in dogs or cats.

Diclazuril Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 456)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei ZB Gamay Biological Technology Co.,Ltd
+86-031189171450 +86-15632359451 chem@zbvet.net China 222 58
shandong perfect biotechnology co.ltd
+86-53169958659; +8618596095638 sales@sdperfect.com China 294 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12453 58
Changzhou Rokechem Technology Co., Ltd.
18758118018 sales001@rokechem.com China 255 58
Anhui Yiao New Material Technology Co., Ltd
+86-199-55145978 +8619955145978 sales8@anhuiyiao.com China 253 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Wuhan Quanjinci New Material Co.,Ltd.
+8615271838296 kyra@quanjinci.com China 1532 58

Related articles

View Lastest Price from Diclazuril manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diclazuril pictures 2024-04-16 Diclazuril
101831-37-2
US $0.00-0.00 / kg 1kg 96% 200kg Hebei ZB Gamay Biological Technology Co.,Ltd
Diclazuril pictures 2024-04-12 Diclazuril
101831-37-2
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Diclazuril pictures 2024-03-26 Diclazuril
101831-37-2
US $0.00 / KG 1KG 99% 2000KG Shaanxi TNJONE Pharmaceutical Co., Ltd
  • Diclazuril pictures
  • Diclazuril
    101831-37-2
  • US $0.00-0.00 / kg
  • 96%
  • Hebei ZB Gamay Biological Technology Co.,Ltd
  • Diclazuril pictures
  • Diclazuril
    101831-37-2
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Diclazuril pictures
  • Diclazuril
    101831-37-2
  • US $0.00 / KG
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd

Diclazuril Spectrum

2,6-Dichloro-a-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile Nuoqiu Vecoxan 2-[3,5-Dichloro-4-(α-cyano-4-chlorobenzyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione 2-[4-(4-Chloro-α-cyanobenzyl)-3,5-dichlorophenyl]-1,2,4-triazine-3,5(2H,4H)-dione CLINACOX DICLAZURIL DICLAZUTIL Diclazuril premix 0.5%,1% Diclazuril 0.5% 1% premix Qiujia DiclazurilCpv2000 clinazox R-64433 2,6-dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl]benzeneacetonitrile iclazuril Diclazuril 0 Diclazuril (200 mg) 2,6-Dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)- Diclazuril HOUSE STANDARD Soluble Diclazuril Diclazuril premixes 2,6-DICHLORO-A-(4-CHLOROPHENYL)-4(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2-YL)BENZENEACETONITRILE 2,6-DICHLORO-ALPHA-(4-CHLOROPHENYL)-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2 (3H)-YL)BENZENEACETONITRILE 2,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3h)-yl)benzeneacetonitrile (4-chlorophenyl)[2,6-dichloro-3-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl]acetonitrile (4-chlorophenyl)[2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl]acetonitrile Diclazuril 101831-37-2 2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile Diclazuril for system suitability CRS Diclazuril powder Benzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)- Diclazuril solution in Acetonitrile/DMF, 1000μg/mL 2-(4-Chlorophenyl)-2-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetonitrile 2,6-Dichloro-alpha-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile Diclazuril USP/EP/BP DICLAZURIL PREMIX 0.5% DiclazurilQ: What is Diclazuril Q: What is the CAS Number of Diclazuril Q: What is the storage condition of Diclazuril Q: What are the applications of Diclazuril Diclazuril (1188560) To g beads Diclozuril 3'-FLUORO-54'-(TRIFLUOROMETHYL)ACETOPHENONE DiclazurilSoiuble Sildenafil Impurity 76-d3 101831-37-2 831-37-2 C17H9Cl3N4O2 Pharmaceuticals Aromatics Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides Veterinaries 101831-37-2