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5-Methyluridine

CAS No.
1463-10-1
Chemical Name:
5-Methyluridine
Synonyms
RIBOTHYMIDINE;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione;1-(BETA-D-RIBOFURANOSYL)THYMINE;5-Me-U;5-Me-Ur;Methyluridine;5-methyuridine;ribosylthymine;5-methyl-uridin;THYMINERIBOSIDE
CBNumber:
CB1322473
Molecular Formula:
C10H14N2O6
Molecular Weight:
258.23
MDL Number:
MFCD00006535
MOL File:
1463-10-1.mol
Last updated:2023-10-11 17:37:18

5-Methyluridine Properties

Melting point 183-184 °C(lit.)
Density 1.576±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
pka 9.55±0.10(Predicted)
form powder
color white
InChI InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey DWRXFEITVBNRMK-JXOAFFINSA-N
SMILES OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O
CAS DataBase Reference 1463-10-1(CAS DataBase Reference)
FDA UNII ZS1409014A

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  24/25
WGK Germany  3
HS Code  29349990
NFPA 704
1
0 0

5-Methyluridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R752002 5-METHYLURIDINE AldrichCPR 1463-10-1 25MG $29.8 2024-03-01 Buy
Sigma-Aldrich 535893 5-Methyluridine 97% 1463-10-1 25g $89.3 2023-06-20 Buy
Sigma-Aldrich 535893 5-Methyluridine 97% 1463-10-1 100g $235 2023-06-20 Buy
TCI Chemical M1405 5-Methyluridine >98.0%(HPLC)(T) 1463-10-1 1g $21 2024-03-01 Buy
TCI Chemical M1405 5-Methyluridine >98.0%(HPLC)(T) 1463-10-1 5g $29 2024-03-01 Buy
Product number Packaging Price Buy
R752002 25MG $29.8 Buy
535893 25g $89.3 Buy
535893 100g $235 Buy
M1405 1g $21 Buy
M1405 5g $29 Buy

5-Methyluridine Chemical Properties,Uses,Production

Description

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.

Chemical Properties

White Powder

Uses

A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

Definition

ChEBI: Ribothymidine is a methyluridine having a single methyl substituent at the 5-position on the uracil ring. It has a role as a human metabolite, an Escherichia coli metabolite and an antigen.

3180-76-5
93-89-0
55-21-0
1463-10-1
Synthesis of 5-Methyluridine from Uridine, 5-methyl-, 2',3',5'-tribenzoate
Global( 432)Suppliers
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Wuhu Nuowei chemistry Co., Ltd.
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Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58

View Lastest Price from 5-Methyluridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Methyluridine pictures 2024-03-16 5-Methyluridine
1463-10-1
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
5-Methyluridine pictures 2023-10-11 5-Methyluridine
1463-10-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
5-Methyluridine pictures 2023-09-06 5-Methyluridine
1463-10-1
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
  • 5-Methyluridine pictures
  • 5-Methyluridine
    1463-10-1
  • US $0.00 / KG
  • 98%+
  • WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
  • 5-Methyluridine pictures
  • 5-Methyluridine
    1463-10-1
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • 5-Methyluridine pictures
  • 5-Methyluridine
    1463-10-1
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
5-methyl-uridin 5-methyuridine 5-Methyluridine (Patent ) THYMINERIBOSIDE URIDINE, 5-METHYL- 5-METHYLURIDINE(5-Methyl-1-ˉ-ribofuranosyl uracil 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 5-methyluridine/ribothymidine ribosylthymine/5-methyluridine Methyluridine 5-Me-U 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione RibosylthyMine(5-Methyluridine,RibothyMidine) 1-β-D-Ribofuranosylthymine 5-Methyl-1-β-D-ribofuranosyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-quinone 5-Methyluridine, >=99% 5-Methyluridine≥ 99% (HPLC) 5-METHYLURIDINE 5-METHYL-D-URIDINE 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL 1-(BETA-D-RIBOFURANOSYL)THYMIDINE BETA-D-THYMINE RIBOSIDE BETA-RIBOFURANOSIDE ribosylthymine 5-methyluridine (produced by synthesis) 5-Me-Ur 5-Methyluridine> 5-Methyluridine USP/EP/BP 5-Methyluridine extrapure, 98% 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione 1-(BETA-D-RIBOFURANOSYL)THYMINE RIBOTHYMIDINE 5-Methyluridine, RNA modified ribo-nucleoside m5U 5-Methyfuridine 1463-10-1 1436-10-1 1463-10-3 C10H14N2O6 Specialty Synthesis Nucleosides Oligonucleotide Synthesis Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs BioChemical Biochemicals and Reagents Carbohydrates & Derivatives Heterocycles Biochemistry Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents Bases & Related Reagents Nucleotides Pyridines, Pyrimidines, Purines and Pteredines Miscellaneous Biochemicals Nucleotides and Nucleosides bc0001