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FENFLURAMINE

FENFLURAMINE
FENFLURAMINE structure
CAS No.
458-24-2
Chemical Name:
FENFLURAMINE
Synonyms
Acino;Pesos;S-768;C06996;EQUINE;Obedrex;Adipomin;Ponderex;Pondimin;Rotondin
CBNumber:
CB1325500
Molecular Formula:
C12H16F3N
Formula Weight:
231.26
MOL File:
458-24-2.mol

FENFLURAMINE Properties

Melting point:
170°C
Boiling point:
bp12 108-112°
Density 
1.0950 (estimate)
storage temp. 
?20°C
pka
pKa 9.10 (Uncertain)

SAFETY

Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  16-36/37-45
Toxicity LD50 i.p. in mice: 144 mg/kg

FENFLURAMINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

FENFLURAMINE Chemical Properties,Uses,Production

Uses

Anorexic.

Definition

ChEBI: A secondary amino compound that is 1-phenyl-propan-2-amine in which one of the meta-hydrogens is substituted by trifluoromethyl, and one of the hydrogens attached to the nitrogen is substituted by an ethyl group. It binds to the serotonin reu take pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding ehavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine was used as the hydrochloride for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertensio .

brand name

Pondimin (Robins).

World Health Organization (WHO)

Fenfluramine, dexfenfluramine and phentermine were approved individually more than 20 years ago in the USA for single-drug, short-term treatment of obesity. The manufacturers of fenfluramine and dexfenfluramine have since voluntarily withdrawn both products from the market worldwide. Phentermine remains available.

FENFLURAMINE Preparation Products And Raw materials

Raw materials

Preparation Products


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458-24-2(FENFLURAMINE)Related Search:


  • FENFLURAMINE
  • AURORA KA-7683
  • AURORA KA-7684
  • 1-(meta-Trifluoromethyl-phenyl)-2 ethylaminopropane
  • Phenethylamine, N-ethyl-alpha-methyl-m-(trifluoromethyl)-
  • 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
  • Acino
  • Adipomin
  • N-Ethyl-1-[3-(trifluoromethyl)phenyl]-2-propanamine
  • N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine
  • Obedrex
  • Pesos
  • Ponderax PA
  • Ponderex
  • Pondimin
  • Rotondin
  • ethyl(alpha-methyl-3-trifluoromethylphenethyl)amine
  • Phenfluoramine
  • n-ethyl-alpha-methyl-m-(trifluoromethyl)-phenethylamin
  • n-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine
  • FENCLORIN
  • N-Ethyl-α-methyl-3-(tfifluoromethyl)benzeneethanamine
  • Ponderal:Pon-derax
  • S-768
  • Fenfluramin
  • N-Ethyl-3-trifluoromethyl-α-methylbenzeneethanamine
  • N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine
  • N-Ethyl-α-methyl-m-(trifluoromethyl)benzeneethanamine
  • dl-Fenfluramine
  • C06996
  • Methanol(Test Fenfluramine, 1.0 mg/mL)
  • FenfluraMine API
  • EQUINE
  • Fenfluramine solution
  • 458-24-2
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