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4-Chlorophenylhydrazine hydrochloride

4-Chlorophenylhydrazine hydrochloride Structure
4-Chlorophenylhydrazine hydrochloride structure
CAS No.
1073-70-7
Chemical Name:
4-Chlorophenylhydrazine hydrochloride
Synonyms
CHLOROPHENYLHYDRAZINE(4-) HCL;LABOTEST-BB LT01147712;P-CHLOROPHENYLHYDRAZINE HCL;P-Chloropheyl hydrazine HCl;4-CHLOROPHENYLHYDRAZINE HCL;p-Chlorphenylhydrazinhydrochlorid;4-chlorophenyl hydrazine, 98%min;hlorophenylhydrazine hydrochloride;Chlorphenylhydrazine hydrochloride;P-CHLOROPHENYLHYDRAZINE HYDROCHLORIDE
CBNumber:
CB1330472
Molecular Formula:
C6H8Cl2N2
Molecular Weight:
179.05
MDL Number:
MFCD00012943
MOL File:
1073-70-7.mol
Last updated:2025-09-02 17:37:48
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4-Chlorophenylhydrazine hydrochloride Properties

Melting point 216 °C (dec.)(lit.)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form Crystalline Powder
color White to pink
Water Solubility Soluble in hot water, methanol.
BRN 3596254
InChI InChI=1S/C6H7ClN2.ClH/c7-5-1-3-6(9-8)4-2-5;/h1-4,9H,8H2;1H
InChIKey YQVZREHUWCCHHX-UHFFFAOYSA-N
SMILES N(C1=CC=C(Cl)C=C1)N.[H]Cl
CAS DataBase Reference 1073-70-7(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  36/37-36-26
RIDADR  2811
WGK Germany  3
Hazard Note  Harmful/Irritant
HazardClass  6.1(b)
PackingGroup  III
HS Code  29280090
NFPA 704
1
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4-Chlorophenylhydrazine hydrochloride price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C65807 4-Chlorophenylhydrazine hydrochloride 98% 1073-70-7 5g $56.3 2025-07-31 Buy
Sigma-Aldrich C65807 4-Chlorophenylhydrazine hydrochloride 98% 1073-70-7 25g $105 2025-07-31 Buy
TCI Chemical C0257 4-Chlorophenylhydrazine Hydrochloride >98.0%(HPLC)(T) 1073-70-7 25g $95 2025-07-31 Buy
TCI Chemical C0257 4-Chlorophenylhydrazine Hydrochloride >98.0%(HPLC)(T) 1073-70-7 250g $614 2025-07-31 Buy
Usbiological 267343 4-Chlorophenylhydrazine HCl 1073-70-7 100g $322 2021-12-16 Buy
Product number Packaging Price Buy
C65807 5g $56.3 Buy
C65807 25g $105 Buy
C0257 25g $95 Buy
C0257 250g $614 Buy
267343 100g $322 Buy

4-Chlorophenylhydrazine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

white to pink crystalline powder

Uses

4-Chlorophenylhydrazine hydrochloride is used as a pharmaceutical intermediates.

General Description

4-Chlorophenylhydrazine hydrochloride reacts with 3-acetonyl-5-cyano-1,2,4-thiadiazole to yield 5-cyano-3-(5-chloro-2-methylindol-3-yl)-1,2,4-thiadiazole and 5-cyano-3-[1-(4-chlorophenyl)-3,5-dimethylpyrazol-4-yl]-1,2,4-thiadiazole.

Synthesis

4-Bromochlorobenzene

106-39-8

4-Chlorophenylhydrazine hydrochloride

1073-70-7

The general procedure for the synthesis of p-chlorophenylhydrazine hydrochloride from 4-bromochlorobenzene is as follows: 98.25 g of 4-bromochlorobenzene and 3.3 equivalents of 71% hydrazine hydrate were added to a reaction vessel, to which were added 10 wt.% of the phase transfer catalyst PEG400, 3 times the weight of the solvent acrylhydrazine, and 20 wt.% of a catalyst (copper sulfate in the ratio of copper sulfate to cobalt chloride by mass of 3:1). The reaction process consisted of slowly increasing the temperature to 152 °C, refluxing or packing pressure reaction at atmospheric pressure, and maintaining the reaction at this temperature for 10 hours. During this time, the reaction process was monitored by HPLC and stopped when the amount of p-chlorophenylhydrazone no longer increased. After completion of the reaction, the solid was separated by filtration and the filtrate was distilled to remove the solvent. To the obtained residue, 30% hydrochloric acid was added, the pH was adjusted to 3, and the residue was filtered with thorough stirring. The filtrate was washed with water and dried at 55°C to finally obtain p-chlorophenylhydrazine hydrochloride. In this embodiment, the yield of p-chlorophenylhydrazine hydrochloride was 88.1% and the HPLC purity was 99.29%.

References

[1] Patent: CN105968048, 2016, A. Location in patent: Paragraph 0030-0054; 0055-0059; 0060-0069
[2] Patent: CN106045876, 2016, A. Location in patent: Paragraph 0055; 0056; 0057; 0058; 0059
[3] Chinese Journal of Chemistry, 2018, vol. 36, # 11, p. 1003 - 1006
[4] Tetrahedron, 2014, vol. 70, # 26, p. 4043 - 4048

4-Chlorophenylhydrazine hydrochloride synthesis

2028-74-2
1073-70-7
Synthesis of 4-Chlorophenylhydrazine hydrochloride from Benzenediazonium, 4-chloro-, chloride

4-Chlorophenylhydrazine hydrochloride Preparation Products And Raw materials

Raw materials

4-Bromochlorobenzene 4-Chloroaniline Benzenediazonium, 4-chloro-, chloride Copper(II) sulfate Cobalt chloride
Hydrochloric acid Hydrazine hydrate Propylene glycol Water

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Preparation Products

Ethyl 5-chloro-2-indolecarboxylate 5-Chloroindole-2-carboxylic acid 5-CHLORO-1H-INDOLE-2-CARBALDEHYDE 4'-CHLORO-BIPHENYL-4-YLAMINE 1-(4-Chlorophenyl)-3-methyl-2-pyrazolin-5-one
4,4'-DICHLORODIPHENYL DISULFIDE 1-(4-CHLOROPHENYL)-3-HYDROXY-1H-PYRAZOLE ETHYL 1-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE 1,3-Cyclohexanedione, mono[(4-chlorophenyl)hydrazone] (9CI) ETHYL 1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE
5-Amino-1-(4-chloro-phenyl)-1H-pyrazole-4-carboxylic acid amide Propanoic acid, 2-[2-(4-chlorophenyl)hydrazinylidene]-, ethyl ester, (2E)- Nsc21429 4,5-Dibromo-2-(4-chloro-phenyl)-2H-pyridazin-3-one

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4-Chlorophenylhydrazine hydrochloride Suppliers

Global( 624)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd 		+8613288715578 sales@hbmojin.com China 12433 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5251 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9297 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20193 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29733 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 12869 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Aochuang Chemical Co.,Ltd. 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55

View Lastest Price from 4-Chlorophenylhydrazine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chlorophenylhydrazine hydrochloride pictures 2025-09-02 4-Chlorophenylhydrazine hydrochloride
1073-70-7
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
4-Chlorophenylhydrazine hydrochloride pictures 2025-08-29 4-Chlorophenylhydrazine hydrochloride
1073-70-7
 US $30.00 / g 99.66% 10g TargetMol Chemicals Inc.
4-Chlorophenylhydrazine hydrochloride pictures 2025-06-24 4-Chlorophenylhydrazine hydrochloride
1073-70-7
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd

4-Chlorophenylhydrazine hydrochloride Spectrum

4-Chlorophenylhydrazine hydrochloride(1073-70-7)MS4-Chlorophenylhydrazine hydrochloride(1073-70-7)1HNMR4-Chlorophenylhydrazine hydrochloride(1073-70-7)IR14-Chlorophenylhydrazine hydrochloride(1073-70-7)IR24-Chlorophenylhydrazine hydrochloride(1073-70-7)IR3

1073-70-7(4-Chlorophenylhydrazine hydrochloride)Related Search:

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4-Methylphenylhydrazine hydrochloride D-Glucosamine hydrochloride Topotecan hydrochloride

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LABOTEST-BB LT01147712 CHLOROPHENYLHYDRAZINE(4-) HCL 1-(4-CHLOROPHENYL)HYDRAZINE HYDROCHLORIDE 4-CHLORO PHENYL HYDRAZXINE HYDROCHLORIDE 4-Chlorophenylhydrazine hydrochloride 97% Hydrazine, (4-chlorophenyl)-, monohydrochloride 4-Chlorophenylhydrazine hydrochloride,97% 4-Hydrazino-1-chlorobenzene hydrochloride 4-Chlorophenylhydrazine hydrochloride, 97% 25GR 4-Chlorophenylhydrazine hydrochloride, 97% 5GR 4 - chlorobenzene hydrazine hydrochloride P-CHLOROPHENYLHYDRAZINE HCL P-CHLOROPHENYLHYDRAZINE HYDROCHLORIDE 1-[3,5-Di(tert-butyl)-4-hydroxybenzylidene]-2-(4-chlorophenyl)hydrazine P-Chloropheyl hydrazine HCl P-Chlorophenyluhydrazinehydrochloride 4-CHLOROPHENYLHYDRAZINE HCL 4-CHLOROPHENYLHYDRAZINE HYDROCHLORIDE hlorophenylhydrazine hydrochloride 4-Chlorophenylhydrazine Hydrochloride > Chlorphenylhydrazine hydrochloride 4-CHLOROPHENYLHYDRAZINE HYDROCHLORIDE 1073-70-7 4-Chlorophenylhydrazine hydrochloride ISO 9001：2015 REACH Chlorobenzene hydrazine hydrochloride 4-Chlorophenylhydrazine hydrochloride CAS NO.1073-70-7 Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) (4-chlorophenyl)-Hydrazine hydrochloride (1:1) Para-Chlorophenyl Hydrazine Hydrochloride p-Chlorphenylhydrazinhydrochlorid 4-chlorophenyl hydrazine, 98%min 1073-70-7 1073-70-3 C6H7ClN2HClC6H8Cl2N2 C6H7ClN2HCl Building Blocks Organic Building Blocks Hydrazines Nitrogen Compounds Hydrazines Nitrogen Compounds Organic Building Blocks Phenylhydrazine Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes Intermediates API 1073-70-7 john's