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Maleimide-NH-PEG12-CH2CH2COOPFP Ester

CAS No.
2136296-33-6
Chemical Name:
Maleimide-NH-PEG12-CH2CH2COOPFP Ester
Synonyms
Mal-NH-PEG12-CH2CH2COOPFP ester;Maleimide-NH-PEG12-CH2CH2COOPFP Ester;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber:
CB13309446
Molecular Formula:
C40H59F5N2O17
Molecular Weight:
934.89
MDL Number:
MFCD34470033
MOL File:
2136296-33-6.mol
Last updated:2023-02-23 14:24:01

Maleimide-NH-PEG12-CH2CH2COOPFP Ester Properties

Boiling point 872.2±65.0 °C(Predicted)
Density 1.272±0.06 g/cm3(Predicted)
pka 15.01±0.46(Predicted)

Maleimide-NH-PEG12-CH2CH2COOPFP Ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
purepeg 436312 Maleimide-NH-PEG12-CH2CH2COOPFPEster min.95% 2136296-33-6 250mg $340 2021-12-16 Buy
Product number Packaging Price Buy
436312 250mg $340 Buy

Maleimide-NH-PEG12-CH2CH2COOPFP Ester Chemical Properties,Uses,Production

Biological Activity

Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Maleimide-NH-PEG12-CH2CH2COOPFP Ester Preparation Products And Raw materials

Raw materials

Preparation Products

Maleimide-NH-PEG12-CH2CH2COOPFP Ester Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Chemleader Biomedical Co., Limited. 021-58180488 sales@MedChemLeader.com China 999 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Nantong Hanfang Biotechnology Co. , Ltd. 3674309880 hanfangpharma@126.com China 30968 58
Maleimide-NH-PEG12-CH2CH2COOPFP Ester Mal-NH-PEG12-CH2CH2COOPFP ester 4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester 2136296-33-6