ChemicalBook >> CAS DataBase List >>Maleimide-NH-PEG12-CH2CH2COOPFP Ester
Maleimide-NH-PEG12-CH2CH2COOPFP Ester
- CAS No.
- 2136296-33-6
- Chemical Name:
- Maleimide-NH-PEG12-CH2CH2COOPFP Ester
- Synonyms
- Mal-NH-PEG12-CH2CH2COOPFP ester;Maleimide-NH-PEG12-CH2CH2COOPFP Ester;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester
- CBNumber:
- CB13309446
- Molecular Formula:
- C40H59F5N2O17
- Molecular Weight:
- 934.89
- MDL Number:
- MFCD34470033
- MOL File:
- 2136296-33-6.mol
Last updated:2023-02-23 14:24:01
Maleimide-NH-PEG12-CH2CH2COOPFP Ester Chemical Properties,Uses,Production
Biological Activity
Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Maleimide-NH-PEG12-CH2CH2COOPFP Ester Preparation Products And Raw materials
Raw materials
Preparation Products
Maleimide-NH-PEG12-CH2CH2COOPFP Ester Suppliers
Global( 6)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Chemleader Biomedical Co., Limited. | 021-58180488 | sales@MedChemLeader.com | China | 999 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
Nantong Hanfang Biotechnology Co. , Ltd. | 3674309880 | hanfangpharma@126.com | China | 30968 | 58 |
Maleimide-NH-PEG12-CH2CH2COOPFP Ester
Mal-NH-PEG12-CH2CH2COOPFP ester
4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester
2136296-33-6