Adenine hydrochloride
- CAS No.
- 2922-28-3
- Chemical Name:
- Adenine hydrochloride
- Synonyms
- ADENINE HCL;6-AMINOPURINE HCL;ADENINIUM CHLORIDE;TIMTEC-BB SBB003841;Adenine hydrocloride;ADENINE HYDROCHLORIDE;7H-adenine hydrochloride;ADENINE MONOHYDROCHLORIDE;Adenine hydrochloride ,98%;6-AMINOPURINE HYDROCHLORIDE
- CBNumber:
- CB1334849
- Molecular Formula:
- C5H6ClN5
- Molecular Weight:
- 171.59
- MDL Number:
- MFCD00075782
- MOL File:
- 2922-28-3.mol
- MSDS File:
- SDS
| Melting point | ~285 °C (dec.) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | White to Off-White |
| Merck | 14,152 |
| BRN | 4009585 |
| CAS DataBase Reference | 2922-28-3(CAS DataBase Reference) |
| FDA UNII | 364H11M7OD |
| EPA Substance Registry System | 1H-Purin-6-amine, monohydrochloride (2922-28-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301-H315-H319 | |||||||||
| Precautionary statements | P270-P301+P310a-P321-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36-36/37/39-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-8 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
Adenine hydrochloride price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A8751 | Adenine hydrochloride hydrate ≥99% | 2922-28-3 | 1g | $40.08 | 2024-03-01 | Buy |
| Sigma-Aldrich | 01840 | Adenine monohydrochloride ≥99.0% (HPLC) | 2922-28-3 | 25g | $51 | 2024-03-01 | Buy |
| TCI Chemical | A0150 | Adenine Hydrochloride Hemihydrate >98.0%(T) | 2922-28-3 | 5g | $27 | 2022-04-27 | Buy |
| TCI Chemical | A0150 | Adenine Hydrochloride Hemihydrate >98.0%(T) | 2922-28-3 | 25g | $79 | 2022-04-27 | Buy |
| Alfa Aesar | A17622 | Adenine hydrochloride, 98+%, cont. up to ca 5% water | 2922-28-3 | 5g | $24.65 | 2024-03-01 | Buy |
Adenine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
Adenine hydrochloride hydrate has been used:
- As a component of FAD cell culture media
- In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
- In limbal-corneal epithelial culturing and keratinocytes
Uses
Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD) and signaling molecules (cAMP).
Biological Activity
adenine hcl, a purine derivative and a nucleobase, plays crucial roles in substantial biochemistry processes in vivo, including cellular respiration, formation of the energy-rich adenosine triphosphate (atp), the cofactors nicotinamide adenine dinucleotide (nad) and flavin adenine dinucleotide (fad) as well as protein synthesis. in addition, adenine hcl also serves as a chemical component of dna and rna. adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between chemical reactions. [1]
in vitro
the cyto-protective effect of adenosine was measured using an in vitro model of acute tubular necrosis in rat kidney tubular cells. the finding suggested that adenosine at the concentration of 100 m could significantly decrease cellular injury. the ec50 value of adenosine was detected to be 14 m. [2]
in vivo
a study was performed to investigate the effects of dietary adenine on fatty liver induced by orotic acid (oa) in rats. 1% oa-supplemented diets with/ without 0.25% adenine was administered to rats for 10 days. enzyme assay kits were then applied to measure serum lipid profiles of tested rats, such as liver lipid concentrations in different treatment groups. moreover, the activities of fatty acid synthase (fas) and fatty acid β-oxidation were also detected. the findings suggested that addition of adenine to the diet offset the effect of oa and reversed promotion of liver tg content to basal level. administration of adenine also inhibited fas activities in rat liver. in conclusion, the ameliorating of fatty liver in adenine-treated rats was associated with the reduction of fas activities accompanied with the increase of mitochondrial fatty acid β-oxidation and the promotion of serum lipid secretion from the hepatic tissue into the bloodstream. [1]
storage
Desiccate at RT
References
[1]buang y. dietary adenine alleviates fatty liver induced by orotic acid. indo. j. chem. 2010; 10 (3): 363 - 369.
[2] módis k, ger d, nagy n, szoleczky p, tóth zd and szabó c. cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis. br j pharmacol. 2009 nov; 158(6): 1565–8.
Adenine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Adenine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-15 | Adenine hydrochloride
2922-28-3
|
US $60.00 / KG | 25KG | 99.99% | 200ton | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-07-06 | ADENINE HYDROCHLORIDE HEMIHYDRATE
2922-28-3
|
US $70.00 / kg | 1kg | 99% | 30 tons | Hebei Duling International Trade Co. LTD | |
 |
2023-06-27 | Adenine hydrochloride
2922-28-3
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
-
- Adenine hydrochloride
2922-28-3
- US $60.00 / KG
- 99.99%
- Hebei Mojin Biotechnology Co., Ltd
-
- ADENINE HYDROCHLORIDE HEMIHYDRATE
2922-28-3
- US $70.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
-
- Adenine hydrochloride
2922-28-3
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
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