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AC 186

AC 186 Structure
AC 186 structure
CAS No.
1421854-16-1
Chemical Name:
AC 186
Synonyms
AC 186;4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol;Phenol, 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]-
CBNumber:
CB13356112
Molecular Formula:
C18H17F3O
Molecular Weight:
306.32
MDL Number:
MFCD28502295
MOL File:
1421854-16-1.mol
Last updated:2023-06-30 15:45:59
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AC 186 Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

AC 186 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 5053 AC186 ≥99%(HPLC) 1421854-16-1 10 $227 2021-12-16 Buy
Tocris 5053 AC186 ≥99%(HPLC) 1421854-16-1 50 $925 2021-12-16 Buy
Usbiological 254507 AC 186 1421854-16-1 10mg $489 2021-12-16 Buy
TRC A305300 AC186 1421854-16-1 5mg $880 2021-12-16 Buy
Ambeed A958678 4-(4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl)phenol 99% 1421854-16-1 100mg $1103 2021-12-16 Buy
Product number Packaging Price Buy
5053 10 $227 Buy
5053 50 $925 Buy
254507 10mg $489 Buy
A305300 5mg $880 Buy
A958678 100mg $1103 Buy

AC 186 Chemical Properties,Uses,Production

Uses

AC 186 is a selective estrogen receptor β (ERβ) agonist moderates cognitive deficits and amyloid-β levels in a mouse model of Alzheimer’s Disease. AC 186 also shows gender specific neuroprotection in a Parkinsons disease rat model.

storage

Store at RT

AC 186 synthesis

1421854-34-3
108-95-2
1421854-16-1
Synthesis of AC 186 from Benzene, 1-(4,4-difluoro-1-cyclohexen-1-yl)-2-fluoro- and Phenol

AC 186 Preparation Products And Raw materials

Raw materials

Benzene, 1-(4,4-difluoro-1-cyclohexen-1-yl)-2-fluoro- Cyclohexanone, 4-(2-fluorophenyl)-4-(4-hydroxyphenyl)- Methanesulfonic acid, 1,1,1-trifluoro-, 4,4-difluoro-1-cyclohexen-1-yl ester 4,4-DIFLUOROCYCLOHEXANONE 2-FLUORO-4'-HYDROXYBENZOPHENONE
Phenol

1of2

Preparation Products

AC 186 Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Nanjing Chemlin Chemical Co., Ltd 025-83697070 info@chemlin.com.cn China 17987 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9445 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255 63313187@qq.com China 1971 58
Tianjin Nuokang Pharmaceutical Technology Co., Ltd. 022-23989838 13810451150 44766350@qq.com China 1473 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
Nanjing Chemlin Chemical Co., Ltd 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
Shanghai Hongye Biotechnology Co. Ltd 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 58
Tianjin Nuokang Pharmaceutical Technology Co., Ltd. 58
AC 186 4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol Phenol, 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]- 1421854-16-1