ANTI-MCL-1
- CAS No.
- Chemical Name:
- ANTI-MCL-1
- Synonyms
- Anti-TM;Anti-EAT;mcl1/EAT;Anti-MCI1;EAT/MCL-1;Anti-MCL1L;Anti-MCL1S;ANTI-MCL-1;Anti-APOER2;Anti-BCL2L3
- CBNumber:
- CB1338751
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01324498
- MOL File:
- Mol file
| storage temp. | −20°C |
|---|---|
| form | buffered aqueous solution |
| FDA UNII | 566CLA8XXQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312-H412 |
| Precautionary statements | P273-P301+P312+P330-P302+P352+P312 |
| Hazard Codes | T |
| Risk Statements | 24/25-52/53 |
| Safety Statements | 36/37-45-61 |
| WGK Germany | - |
ANTI-MCL-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4501844 | Anti-MCL1 antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4501843 | Anti-MCL1 antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2103110 | Anti-LRP8 antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | M8434 | Anti-Mcl-1 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 0.2ML | $528 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA031125 | Anti-MCL1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy |
ANTI-MCL-1 Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Immunohistochemistry (1 paper)
General Description
Induced myeloid leukemia cell differentiation protein Mcl-1(MCL1) belongs to the Bcl-2 family and contains the characteristic Bcl-2 homology (BH) domain. The gene encoding this protein is present on chromosome 1q21.
Biochem/physiol Actions
Induced myeloid leukemia cell differentiation protein Mcl-1(MCL1) plays an important role in inhibiting apoptosis and is expressed only during particular stages of cell differentiation and in response to specific signals. It is a viability-promoting protein that interacts with fortilin (an anti-apoptotic protein) and regulates cell viability. Specific differentiation- and apoptosis-inducing stimuli enhance the expression of this protein. MCL1 acts as a chaperone of fortilin by binding and stabilizing it. It also interacts and negatively regulates the proliferating cell nuclear antigen (PCNA), which a cell cycle-regulatory protein essential for G1 to S phase transition. Hence, it functions to retard the cell cycle progression.
ANTI-MCL-1 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MCL-1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |