ChemicalBook
Chinese Japanese Germany Korea

TRIOXSALEN

TRIOXSALEN
TRIOXSALEN structure
CAS No.
3902-71-4
Chemical Name:
TRIOXSALEN
Synonyms
LACTONE;NSC-71047;Trioxalen;Trioxsale;Trixsalen;Elder 8011;TRISORALEN;TRIOXSALEN;TRIOXSALIN;TRIOXYSALEN
CBNumber:
CB1363250
Molecular Formula:
C14H12O3
Formula Weight:
228.24
MOL File:
3902-71-4.mol

TRIOXSALEN Properties

Melting point:
229-231 °C(lit.)
Boiling point:
310.05°C (rough estimate)
Density 
1.2196 (rough estimate)
refractive index 
1.5557 (estimate)
storage temp. 
2-8°C
solubility 
DMSO: soluble
form 
powder
color 
white
Merck 
14,9735
BRN 
221723
CAS DataBase Reference
3902-71-4
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  C
Risk Statements  34-40
Safety Statements  26-36/37/39-45
RIDADR  UN 1759 8/PG 1
WGK Germany  2
RTECS  LV1576000
8-10
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29322985
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

TRIOXSALEN price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1693009 Trioxsalen United States Pharmacopeia (USP) Reference Standard 3902-71-4 200mg $348 2018-11-13 Buy
Sigma-Aldrich T6137 Trioxsalen ≥98% (HPLC), powder 3902-71-4 1g $468 2018-11-13 Buy
TCI Chemical T2267 Trioxsalen >98.0%(HPLC) 3902-71-4 1g $89 2018-11-22 Buy
TCI Chemical T2267 Trioxsalen >98.0%(HPLC) 3902-71-4 5g $269 2018-11-22 Buy
Alfa Aesar J63226 4,5',8-Trimethylpsoralen, 99% 3902-71-4 1g $66.5 2018-11-13 Buy

TRIOXSALEN Chemical Properties,Uses,Production

Chemical Properties

White to slightly beige crystalline powder

Uses

melanizing agent, antipsoriatic

Definition

ChEBI: 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phot therapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermi .

brand name

Trisoralen (Valeant).

Purification Methods

Purify trioxsalen by recrystallisation from CHCl3. If too impure, it is fractionally crystallised from CHCl3/pet ether (b 30-60o) using Norit and finally crystallised from CHCl3 alone to give colourless prisms, m 234.5-235o. It is a photosensitiser so it should be stored in the dark. [UV: Kaufmann J Org Chem 26 117 1961, Baeme et al. J Chem Soc 2976 1949, Beilstein 19/4 V 472.]

TRIOXSALEN Preparation Products And Raw materials

Raw materials

Preparation Products


TRIOXSALEN Suppliers

Global( 70)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40277 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15884 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24560 81
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44046 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32365 50
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13013 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 QQ:452520369
+86 (573) 82222643 sales@maya-r.com China 11744 57
Spectrum Chemical Manufacturing Corp. 021-67601398,18616765336,QQ:3003443155
021-57711696 mkt@spectrumchina.net China 9692 60

3902-71-4(TRIOXSALEN)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved