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2-Ketoglutaric acid

Description References
2-Ketoglutaric acid
2-Ketoglutaric acid
CAS No.
328-50-7
Chemical Name:
2-Ketoglutaric acid
Synonyms
α-KG;328-50-7;KETO-GLU;α-‍FEMA 3891;Oxoglurate;Alpha - ketone;Oxoglutaric acid;-Ketoglutaricacid;β-ketoadipic acid
CBNumber:
CB1371815
Molecular Formula:
C5H6O5
Formula Weight:
146.1
MOL File:
328-50-7.mol

2-Ketoglutaric acid Properties

Melting point:
113-115 °C
Boiling point:
185.67°C (rough estimate)
Density 
1.2821 (rough estimate)
refractive index 
1.3920 (estimate)
FEMA 
3891 | 2-OXOPENTANEDIOIC ACID
storage temp. 
2-8°C
solubility 
H2O: soluble0.1g/mL, clear, colorless
form 
Crystalline Powder
pka
2.47(at 25℃)
color 
White to slightly yellow
Water Solubility 
Soluble in water, methanol and dimethyl sulfoxide.
Merck 
14,5303
BRN 
1705689
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-N
CAS DataBase Reference
328-50-7(CAS DataBase Reference)
NIST Chemistry Reference
2-Oxopentanedioic acid(328-50-7)
EPA Substance Registry System
Pentanedioic acid, 2-oxo-(328-50-7)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,T
Risk Statements  37/38-41-36/37/38-23/24/25
Safety Statements  26-39-45-36/37/39
WGK Germany  3
TSCA  Yes
HS Code  29183000
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

2-Ketoglutaric acid price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 75890 α-Ketoglutaric acid ≥99.0% (T) 328-50-7 25g $33.2 2018-11-20 Buy
Sigma-Aldrich 75890 α-Ketoglutaric acid ≥99.0% (T) 328-50-7 100g $77.9 2018-11-20 Buy
TCI Chemical K0005 2-Oxoglutaric Acid >99.0%(T) 328-50-7 25g $26 2018-11-22 Buy
TCI Chemical K0005 2-Oxoglutaric Acid >99.0%(T) 328-50-7 100g $66 2018-11-22 Buy
Alfa Aesar A10256 2-Ketoglutaric acid, 98% 328-50-7 100g $50.3 2018-11-13 Buy

2-Ketoglutaric acid Chemical Properties,Uses,Production

Description

2-Ketoglutaric acid also known as α-Ketoglutaric acid (AKG) is a chemical found in the body. It is a ketone derivative of the organic compound glutaric acid. It is important for the proper metabolism of all essential amino acids and the transfer of cellular energy in the citric acid or Krebs cycle. In combination with L-glutamate, AKG can reduce levels of ammonia formed in the brain, muscles, and kidneys, as well as help balance the body’s nitrogen chemistry and prevent nitrogen excess in body tissues and fluids.
α-Ketoglutaric acid is used for kidney disease; intestinal and stomach disorders, including bacterial infections; liver problems; cataracts; and recurring yeast infections. It is also used for improving the way kidney patients receiving hemodialysis treatments process protein.

References

[1] http://www.webmd.com
[2] https://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid

Chemical Properties

Crystalline

Uses

A derivative of glutaric acid.

Definition

ChEBI: An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle.

Purification Methods

Crystallise the keto-acid repeatedly from Me2CO/*benzene, EtOAc or ethyl propionate. Dry it in vacuo.[Beilstein 3 IV 1813.]

2-Ketoglutaric acid Preparation Products And Raw materials

Raw materials

Preparation Products


2-Ketoglutaric acid Suppliers

Global( 355)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4525 58
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 894 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1659 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 10967 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19990 58
Chengdu Baishixing Science and Technology Industry Co.,Ltd 15882326242
QQ1410835067 stephen.xu@cd-bsx.com China 118 55

View Lastest Price from 2-Ketoglutaric acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-25 2-Ketoglutaric acid
328-50-7
US $100.00 / KG 100G 98% 10KG,20KG career henan chemical co

2-Ketoglutaric acid Spectrum


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