ChemicalBook >> CAS DataBase List >>2,2,6,6-Tetramethyl-3,5-heptanedione

2,2,6,6-Tetramethyl-3,5-heptanedione

2,2,6,6-Tetramethyl-3,5-heptanedione structure

CAS No.: 1118-71-4

Chemical Name:: 2,2,6,6-Tetramethyl-3,5-heptanedione

Synonyms: TMHD;2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE;DIPIVALOYLMETHANE;2,2,6,6-Tetramethyl heptanedione;2,2,6,6-Tetramethyl-3,5-heptadione;butan-1-ol,propan-2-ol,titanium;3,5-Heptanedione, 2,2,6,6-tetramethyl-;dpm-h;5-heptanedione;6-Tetramethyl-3

CBNumber:: CB1373637

Molecular Formula:: C11H20O2

Molecular Weight:: 184.28

MDL Number:: MFCD00008848

MOL File:: 1118-71-4.mol

MSDS File:: SDS

Last updated:2023-11-29 16:31:21

Request For Quotation

2,2,6,6-Tetramethyl-3,5-heptanedione Properties

Melting point	>400 °C (decomp)
Boiling point	72-73 °C/6 mmHg (lit.)
Density	0.883 g/mL at 25 °C (lit.)
refractive index	n20/D 1.459(lit.)
Flash point	153 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Difficult to mix.
pka	11.60±0.10(Predicted)
form	Liquid
color	Clear colorless to slightly yellow
Specific Gravity	0.883
BRN	1447269
InChIKey	YRAJNWYBUCUFBD-UHFFFAOYSA-N
LogP	2.818 (est)
CAS DataBase Reference	1118-71-4(CAS DataBase Reference)
FDA UNII	R8UI909HOY
EPA Substance Registry System	3,5-Heptanedione, 2,2,6,6-tetramethyl- (1118-71-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227-H302

Precautionary statements

P210e-P264-P280a-P301+P312a-P501a-P210-P280-P370+P378-P403+P235-P501

Hazard Codes

Risk Statements

22-40-36/37/38

Safety Statements

24/25-36-26-22

RIDADR

UN 1993 / PGIII

WGK Germany

TSCA

HS Code

29141900

NFPA 704

	2
1		0

2,2,6,6-Tetramethyl-3,5-heptanedione price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	155756	2,2,6,6-Tetramethyl-3,5-heptanedione 98%	1118-71-4	5g	$49.8	2024-03-01	Buy
Sigma-Aldrich	155756	2,2,6,6-Tetramethyl-3,5-heptanedione 98%	1118-71-4	25g	$144	2024-03-01	Buy
TCI Chemical	D1678	Dipivaloylmethane >97.0%(GC)	1118-71-4	5g	$61	2024-03-01	Buy
TCI Chemical	D1678	Dipivaloylmethane >97.0%(GC)	1118-71-4	25g	$173	2024-03-01	Buy
Alfa Aesar	A15118	2,2,6,6-Tetramethyl-3,5-heptanedione, 98%	1118-71-4	5g	$44.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
155756	5g	$49.8	Buy
155756	25g	$144	Buy
D1678	5g	$61	Buy
D1678	25g	$173	Buy
A15118	5g	$44.65	Buy

2,2,6,6-Tetramethyl-3,5-heptanedione Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID

Uses

suzuki reaction

Uses

2,2,6,6-Tetramethyl-3,5-heptanedione is a beta diketone with antibacterial activity.

Uses

2,2,6,6-tetramethyl-3,5-heptanedione was used in the synthesis of α-aryl-β-diketones1 and dicyanamidobenzene-bridge diruthenium complex.

Definition

2,2,6,6-Tetramethyl-3,5-heptanedioneis a stable, anhydrous reagent. It undergoes O-additions and C-additions. In various reactions, it acts as an air-stable ligand for metal catalysts. Furthermore, it serves as a substrate for heterocycles.

Synthesis Reference(s)

Journal of the American Chemical Society, 100, p. 5428, 1978 DOI: 10.1021/ja00485a030

General Description

Acylation, a replacement to silylation, allows the conversion of compounds that consist of active hydrogens (-OH, -SH and -NH) into esters, thioesters, and amides via the action of a carboxylic acid or derivative. The carbonyl group adjacent to the halogenated carbons is known to improve the electron capture detector (ECD) response. Acylation has several advantages:

It enhances the stability of compounds by protecting unstable groups.
It may confer volatility on substances like carbohydrates or amino acids, that have several polar groups that they are non-volatile and usually decompose on heating.
It facilitates the separations not possible with underivatized compounds.
Compounds are detectable at very low levels with an ECD.

2,2,6,6-Tetramethyl-3,5-heptanedione is a reagent used to form fragmentation-directing derivatives for GC/MS analysis.

Synthesis

Methyl pivalate and formamide could be used as starting materials to synthesize 2,2,6,6-Tetramethyl-3,5-heptanedione.

2,2,6,6-Tetramethyl-3,5-heptanedione synthesis

Synthesis of 2,2,6,6-Tetramethyl-3,5-heptanedione from 4-Heptyn-3-one, 2,2,6,6-tetramethyl-

2,2,6,6-Tetramethyl-3,5-heptanedione Preparation Products And Raw materials

Raw materials

Sodium hydride Ethanol N,N-Dimethylformamide Pinacolone Tetrahydrofuran

Diethyl ether Ethyl acetate Methyl trimethylacetate Hydrochloric acid 4-Heptyn-3-one, 2,2,6,6-tetramethyl-

Benzenemethanamine, N-(1,2,2-trimethylpropylidene)- Dipivaloylamine 2,2-Dimethylpropanoic acid phenyl ester Propanamide,2,2-dimethyl-N-(phenylmethyl)- 2,3,3-TRIMETHYL-2-BUTANOL

8-Hydroxyquinoline

1of4

Preparation Products

N,N-DIPHENYLQUINACRIDONE 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO POTASSIUM 3,5-Heptanedione, 4-bromo-2,2,6,6-tetramethyl-

2,2,6,6-Tetramethyl-3,5-heptanedione Suppliers

Global( 361)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	723	55
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	sales@anbuchem.com	China	3000	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	7838	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58

Supplier	Advantage
Speranza Chemical Co., Ltd.	55
Zhengzhou Anbu Chem Co.,Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Guanlang Biotechnology Co,.LTD	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from 2,2,6,6-Tetramethyl-3,5-heptanedione manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4	US $205.00-195.00 / KG	25KG	98%	500kg	Speranza Chemical Co., Ltd.
2024-04-09	2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4	US $0.00 / KG	1KG	≥98% HPLC	1000KG	Changsha Staherb Natural Ingredients Co., Ltd.
2023-11-08	2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE
1118-71-4
US $205.00-195.00 / KG
98%
Speranza Chemical Co., Ltd.

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE
1118-71-4
US $0.00 / KG
≥98% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE
1118-71-4
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

2,2,6,6-Tetramethyl-3,5-heptanedione Spectrum

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)MS 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)¹HNMR 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)¹³CNMR 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)IR1 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)Raman 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE(1118-71-4)ESR

1118-71-4(2,2,6,6-Tetramethyl-3,5-heptanedione)Related Search:

2,4-HEXANEDIONE 2,2,6,6-Tetramethyl-3,5-heptanedione copper(II) derivative, Cu(TMHD)2,2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE, COPPER(II) DERIVATIVE 2,2,6,6-Tetramethyl-3,5-heptanedione 2,2-DIMETHYL-3,5-HEXANEDIONE 3,5-HEPTANEDIONE

Barium bis(2,2,6,6-tetramethyl-3,5-heptanedionate) hydrate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)LEAD(II) GD(TMHD)3 BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)LEAD(II)

2,2-DIMETHYL-3-HEXANONE 2,6-DIMETHYL-3,5-HEPTANEDIONE BISMUTH TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATE) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)YTTRIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)YTTERBIUM

2,6-HEPTANEDIONE 2,2-DIMETHYL-3-HEPTANONE 4,4-DIMETHYL-3-OXO-PENTANAL

1of4

(CH3)3CCOCH2COC(CH3)3 2,2,6,6-tetramethyl-5-heptanedione 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE DIPIVALOYLMETHANE 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE Dipivaloylmethane~Dpm-H~Tmhd-H 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE, 95 % 2,2,6,6-Tetramethylheptane-3,5-dione,98%TMHD dpm-h 2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE TMHD 2,2,6,6-Tetramethyl-3,5-heptanedione, 99+% 2,2,6,6-Tetramethyl-3,5-heptanedione, 98+% 1,3-Di-tert-butyl-1,3-propanedione 2,2,6,6-Tetramethylheptane-3,5-dione, 99% TMHD 2,2,6,6-TetraMethyl-3,5-heptanedione, 98% 5GR 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE FOR 2,2,6,6-TetraMethyl-3,5-heptan Dipivaloylmethane, 3,5-Dioxo-2,2,6,6-tetramethylheptane 2,2,6,6-TetraMethylheptane-3,5-dione SynonyMs 1,3-Di-tert-butyl-1,3-propanedione 2,2,6,6-Tetramethylheptane-3,5-dione 98% 5-heptanedione 6-Tetramethyl-3 Dipivaloylmethane> DIPIVALOYALMETHANE -3,5-heptanedione 2,2,6,6-Tetramethylheptane-3,5-dione 1118-71-4 2,2,6,6-Tetramethyl heptanedione TMHD DIPIVALOYLMETHANE 2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE 3,5-Heptanedione, 2,2,6,6-tetramethyl- 2,2,6,6-Tetramethyl-3,5-heptadione butan-1-ol,propan-2-ol,titanium 1118-71-4 11188-71-4 C11H20O2 KETONE Ligands (Environmentally-friendly Oxidation) Environmentally-friendly Oxidation C11 to C12 Carbonyl Compounds Acylation Building Blocks Organic Building Blocks Ketones Achiral Oxygen organic compound Environmentally-friendly Oxidation Ligands (Environmentally-friendly Oxidation) Synthetic Organic Chemistry CHIRAL CHEMICALS