ChemicalBook >> CAS DataBase List >>Bupivacaine hydrochloride
Bupivacaine hydrochloride
- CAS No.
- 14252-80-3
- Chemical Name:
- Bupivacaine hydrochloride
- Synonyms
- Sensorcaine;ah-2250;Bupivocoine HCl;Bupivacaine HCI;Bupivacaine HCL API;marcainehydrochloride;Bupivacaine HCL (USP);BUPIVACAINE HYDROCHLORIDE;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride,>98%
- CBNumber:
- CB1386202
- Molecular Formula:
- C18H28N2O.ClH
- Molecular Weight:
- 324.89
- MDL Number:
- MFCD00941462
- MOL File:
- 14252-80-3.mol
Last updated:2024-04-19 20:05:26
| Melting point | 249-2510C |
|---|---|
| storage temp. | Refrigerator |
| solubility | Soluble in water, freely soluble in alcohol. |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChI | InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H |
| InChIKey | SIEYLFHKZGLBNX-UHFFFAOYSA-N |
| SMILES | C1(CCCCN1CCCC)C(=O)NC1C(C)=CC=CC=1C.Cl |
| CAS DataBase Reference | 14252-80-3(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | bupivacaine hydrochloride; Sensorcaine |
| FDA UNII | 7TQO7W3VT8 |
| NCI Drug Dictionary | bupivacaine hydrochloride |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H330-H300-H310 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 22-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TK6125000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2933399090 |
| Toxicity | LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand) |
Bupivacaine hydrochloride price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1078507 | Bupivacaine hydrochloride United States Pharmacopeia (USP) Reference Standard | 14252-80-3 | 300mg | $366 | 2021-12-16 | Buy |
| TRC | B780598 | Bupivacaine hydrochloride | 14252-80-3 | 100mg | $60 | 2021-12-16 | Buy |
| TRC | B780598 | Bupivacaine hydrochloride | 14252-80-3 | 500mg | $75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001784 | BUPIVACAINE HYDROCHLORIDE 95.00% | 14252-80-3 | 1G | $140.7 | 2021-12-16 | Buy |
| Chemenu | CM249371 | 1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamidehydrochloride 97% | 14252-80-3 | 100g | $210 | 2021-12-16 | Buy |
Bupivacaine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Bupivacaine Hydrochloride is the salt form of Bupivacaine (B689561); is a sodium channel blocker, local anesthetic.
Uses
antineoplastic
Definition
ChEBI: Bupivacaine hydrochloride (anhydrous) is a racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic. It has a role as an adrenergic antagonist, an amphiphile, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor and a local anaesthetic. It contains a levobupivacaine hydrochloride (anhydrous), a dextrobupivacaine hydrochloride (anhydrous) and a bupivacaine(1+).
brand name
Marcaine (Hospira); Sensorcaine (AstraZeneca).
Biological Functions
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.
Bupivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 327)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Godbullraw Chemical Co.,ltd | +undefined18986288449 | Alisasales@godbullraw.com | China | 560 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 | sales8@anhuiyiao.com | China | 253 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 248 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Wuhan Xinhao Biotechnology Co., Ltd | +86-18120578002 +86-18120578002 | xinhao-6@xinhaoshengwu.com | China | 350 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
Related articles
- Bupivacaine hydrochloride: mechanism of action, clinical applications and safety
- Bupivacaine Hydrochloride, a local anesthetic that blocks nerve impulses, is widely used but requires careful usage due to pot....
- Nov 20，2023
- Bupivacaine hydrochloride--Metabolism, Excretion, Pediatric use and recommended dose
- Bupivacaine hydrochloride has particularly long action, and some nerve blocks last more than 24 hours; this is often an advant....
- Oct 15，2020
View Lastest Price from Bupivacaine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | Bupivacaine hydrochloride
14252-80-3
|
US $0.00-0.00 / kg | 1kg | 99% | 500 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2024-04-19 | Bupivacaine hydrochloride
14252-80-3
|
US $3.00-1.00 / kg | 1kg | 99.9% | 10 tons | Shanghai Aosiris new Material Technology Co., LTD | |
 |
2024-04-02 | bupivacaine hydrochloride
14252-80-3
|
US $10.00-100.00 / kg | 1kg | 99% | 5000 MT/Month | Wuhan Xinhao Biotechnology Co., Ltd |
-
- Bupivacaine hydrochloride
14252-80-3
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Bupivacaine hydrochloride
14252-80-3
- US $3.00-1.00 / kg
- 99.9%
- Shanghai Aosiris new Material Technology Co., LTD
-
- bupivacaine hydrochloride
14252-80-3
- US $10.00-100.00 / kg
- 99%
- Wuhan Xinhao Biotechnology Co., Ltd
14252-80-3(Bupivacaine hydrochloride)Related Search:
BUPIVACAINE HYDROCHLORIDE
(+,-)-1-butyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate
Bupivacaine hydrochloride
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride
Bupivacaine Hydrochloride, USP
1-butyl-2’,6’-pipecoloxylididehydrochloride(+-)
2-piperidinecarboxamide,1-butyl-n-(2,6-dimethylphenyl)-monohydrochloride,m
ah-2250
marcainehydrochloride
dl-1-n-Butylpiperidine-2-carboxylic Acid 2,6-Dimethylanilide Hydrochloride
BUPIVACAINEHYDROCHLORIDE,MONOHYDRATE,USP
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride
2-PiperidinecarboxaMide, 1-butyl-N-(2,6-diMethylphenyl)-, hydrochloride (1:1)
2-PiperidinecarboxaMide, 1-butyl-N-(2,6-diMethylphenyl)-, hydrochloride
Bupivacaine HCL API
Bupivocoine HCl
Bupivacaine HCL (USP)
IN STOCK BUPIVACAINE HYDROCHLORIDE CAS NO.14252-80-3
BUPIVACAINE HYDROCHLORIDE CAS NO.14252-80-3
Local Anesthetic Pharmaceutical Raw Material Bupivacaine HCl CAS 14252-80-3
Bupivacaine hydrochloride,>98%
Bupivacaine hydrochloride USP/EP/BP
Bupivacaine Hydrochloride Bupivacaine HCl
Bupivacaine Hydrochloride (1078507)
Sensorcaine
Bupivacaine HCI
14252-80-3
14525-80-3
CAS NO.14252-80
76630-54-0
C18H28N2OHClH2O
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