ChemicalBook >> CAS DataBase List >>N-(Hydroxymethyl)phthalimide
N-(Hydroxymethyl)phthalimide
- CAS No.
- 118-29-6
- Chemical Name:
- N-(Hydroxymethyl)phthalimide
- Synonyms
- AURORA KA-454;N-(HydroxymethyL;AKOS BBS-00004724;IFLAB-BB F0777-0575;PHTHALIMIDOMETHANOL;N-(Hydroxymethyl)ph;oxymethylphthalimide;Phthalimidylmethanol;N-Methylolphthalimide;Oxymethyl phthalimide
- CBNumber:
- CB1392676
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD00005899
- MOL File:
- 118-29-6.mol
- MSDS File:
- SDS
Last updated:2024-04-16 14:59:45
| Melting point | 147-149 °C (lit.) |
|---|---|
| Boiling point | 309.06°C (rough estimate) |
| Density | 1.3312 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | Store below +30°C. |
| form | Fine Crystalline Powder |
| pka | 13.17±0.10(Predicted) |
| color | White |
| BRN | 140946 |
| InChIKey | MNSGOOCAMMSKGI-UHFFFAOYSA-N |
| CAS DataBase Reference | 118-29-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | G8L8BA278J |
| NIST Chemistry Reference | 1H-isoindole-1,3(2h)-dione, 2-(hydroxymethyl)-(118-29-6) |
| EPA Substance Registry System | N-(Hydroxymethyl)phthalimide (118-29-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TI5270000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29251995 | |||||||||
| NFPA 704 |
|
N-(Hydroxymethyl)phthalimide price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H41803 | N-(Hydroxymethyl)phthalimide 97% | 118-29-6 | 100g | $219 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.14422 | N-(Hydroxymethyl)-phthalimide for synthesis | 118-29-6 | 100g | $68.9 | 2024-03-01 | Buy |
| TCI Chemical | H0648 | N-Hydroxymethylphthalimide >98.0%(HPLC)(N) | 118-29-6 | 25g | $35 | 2024-03-01 | Buy |
| TCI Chemical | H0648 | N-Hydroxymethylphthalimide >98.0%(HPLC)(N) | 118-29-6 | 250g | $150 | 2024-03-01 | Buy |
| Alfa Aesar | B21292 | N-(Hydroxymethyl)phthalimide, 97% | 118-29-6 | 25g | $24.65 | 2024-03-01 | Buy |
N-(Hydroxymethyl)phthalimide Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
N-(Hydroxymethyl)phthalimide is used as a reactant in the synthesis of 5-[(3-aralkyl amido/imidoalkyl)phenyl]-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as antiviral agents.
Uses
For amidomethylation of aromatics in triflic acid.
Preparation
To a flask equipped with a mechanical stirrer and condenser is added 511 gm (3.47 moles) of phthalimide, 260 ml of 40% formalin (3.47 moles), and 1750 ml of water. The mixture is refluxed for about 5-10 min or until a clear solution results (if any insoluble material remains, it is first filtered). Then the mixture is cooled for several hours. The resulting product is filtered with suction, washed with cold water, and air-dried to afford 594 gm (96%), m.p. 137-141°C.
NOTE: The product should not be oven-dried since it decomposes with the loss of formaldehyde. Recrystallization of the product from ethanol affords 94% recovery of the original material with the same melting point range.
Definition
ChEBI: A primary alcohol comprising phthalimide carrying an N-hydroxymethyl substituent.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 1913, 1955 DOI: 10.1021/ja01612a068
N-(Hydroxymethyl)phthalimide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 377)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 | sarah@tnjone.com | China | 794 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from N-(Hydroxymethyl)phthalimide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-16 | N-(Hydroxymethyl)phthalimide
118-29-6
|
US $0.00 / kg | 1kg | 99% | 10000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-01-02 | N-(Hydroxymethyl)phthalimide
118-29-6
|
US $90.00-900.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2023-08-15 | N-(Hydroxymethyl)phthalimide
118-29-6
|
US $100.00 / KG | 1KG | 99% | 5000KG | Hebei Mojin Biotechnology Co., Ltd |
-
- N-(Hydroxymethyl)phthalimide
118-29-6
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- N-(Hydroxymethyl)phthalimide
118-29-6
- US $90.00-900.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- N-(Hydroxymethyl)phthalimide
118-29-6
- US $100.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
118-29-6(N-(Hydroxymethyl)phthalimide)Related Search:
2-methylolisoindoline-1,3-quinone
PHTHALIMIDOMETHANOL
N-(HYDROXYMETHYL)PHTHALIMIDE
HYDROXYMETHYL PHTHALIMIDE
IFLAB-BB F0777-0575
AURORA KA-454
2-(hydroxymethyl)-1h-isoindole-3(2h)-dione
2-Hydroxymethyl-isoindole-1,3-dione
Methanol, phthalimido-
n-(hydroxymethyl)-phthalimid
N-Methylolphthalimide
Oxymethyl phthalimide
AKOS BBS-00004724
2-(HYDROXYMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE
oxymethylphthalimide
Phthalimide, N-(hydroxymethyl)-
Phthalimidomethyl alcohol
phthalimidomethylalcohol
4-(Hydroxymethyl)phthalimide, 97%
1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-
N-Hydroxymethylphthalimide, 97 %
N-(Hydroxymethyl)phthalimide, 98+%
2-(Hydroxymethyl)-1,3-dihydro-2H-isoindole-1,3-dione
2-(Hydroxymethyl)isoindoline-1,3-dione
Phthalimidylmethanol
N-(Hydroxymethyl)phthalimide,Phthalimidomethanol
N-(Hydroxymethyl)ph
2-(hydroxymethyl)-1,3-isoindolinedione
2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione, (Phthalimid-1-yl)methanol
N-(HydroxyMrthyl)phthaliMide
N-(HYDROXYMETHYL)-PHTHALIMIDE FOR SYNTHE
N- hydroxyMethyladjacent benzenetwoMethyl iMide
N - hydroxy Methyl phthalates forMyl iMine
N-Hydroxymethylphthalimide
2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione, 2-(Hydroxymethyl)isoindolin-1,3-dione
N-(HydroxymethyL
N-Hydroxymethylphthalimide>
N-Hydroxyl-Methyl phthalimide
2-ACETYL-5-CHLORO-73-METHYLTHIANAPHTHENE
N-(-2-HYDROXYMETHYL) PHTHALIMIDE
118-29-6
N-Substituted Maleimides, Succinimides & Phthalimides
N-Substituted Phthalimides
ALCOHOL
Organic Building Blocks
Cyclic Imides
Carbonyl Compounds
Building Blocks
N-Substituted Maleimides, Succinimides & Phthalimides
N-Substituted Phthalimides
intermediates
fine chemicals
pharmacetical