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ChemicalBook >> CAS DataBase List >>L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Structure
L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID structure
CAS No.
42438-90-4
Chemical Name:
L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Synonyms
TCR;TNCA;L -CarL;H-TPI-OH;H-THNH(3)-OH;Lycoperodine 1;TNCA >=98% (HPLC);RARECHEM BK PT 0088;CYCLOMETHYLTRYPTOPHAN;Tryptophan Impurity M
CBNumber:
CB1395455
Molecular Formula:
C12H12N2O2
Molecular Weight:
216.24
MDL Number:
MFCD00272641
MOL File:
42438-90-4.mol
Last updated:2023-04-23 13:52:06
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L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Properties

Melting point 289 °C (dec.)(lit.)
Boiling point 485.0±45.0 °C(Predicted)
Density 1.377±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility soluble1.5mg/mL, clear (Solvent: 0.1N HCl:DMSO (1:1); warmed)
pka 2.28±0.20(Predicted)
form powder
color white to beige
optical activity [α]/D -57 to -67°, c = 1 (in MeOH:1N HCl (1:1))
InChIKey FSNCEEGOMTYXKY-JTQLQIEISA-N
CAS DataBase Reference 42438-90-4(CAS DataBase Reference)
NCI Dictionary of Cancer Terms TCR

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1711 (S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid ≥98% (HPLC) 42438-90-4 10mg $56.9 2024-03-01 Buy
Sigma-Aldrich SML1711 (S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid ≥98% (HPLC) 42438-90-4 50mg $233 2024-03-01 Buy
TRC T795458 L-1,2,3,4-Tetrahydronorharman-3-carboxylicAcid 42438-90-4 200mg $160 2021-12-16 Buy
AK Scientific Z5873 (S)-(?)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid 42438-90-4 1g $77 2021-12-16 Buy
Chem-Impex 06279 L-1,2,3,4-Tetrahydronorharman-3-carboxylicacid,98% 98% 42438-90-4 5G $78.4 2021-12-16 Buy
Product number Packaging Price Buy
SML1711 10mg $56.9 Buy
SML1711 50mg $233 Buy
T795458 200mg $160 Buy
Z5873 1g $77 Buy
06279 5G $78.4 Buy

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Biochem/physiol Actions

TNCA is a tryptophan derivative that binds the parathyroid Ca2+-sensing receptor (CaSR) extracellular domain (ECD) hinge region between two globular subdomains and acts as a high-affinity CaSR ligand (CaSRL) with co-agonist activity. TNCA is shown to potentiate both Mg++- and Ca++-evoked cellular calcium response (0.1-0.5 mM), as well as Mg++-evoked cellular ERK1/2 phosphorylation in CaSR-expressing HEK293 cells (0.5 mM). AC-265347 (Cat. No. SML0129), on the other hand, is a calcimimetic that functions as a CaSR agonist.

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd. 		+8618080483897 sales@biopurify.com China 3424 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
AFINE CHEMICALS LIMITED 		0571-85134551 info@afinechem.com CHINA 15377 58
BOC Sciences 		+16314854226 inquiry@bocsci.com United States 19743 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Wuhan Han Sheng New Material Technology Co.，Ltd 		+8617798174412 admin01@hsnm.com.cn China 2118 58
Wuhan BJM Pharm Inc 		+86-027-5234-1919 +8613545198479 sales03@benjaminpharmchem.com China 671 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Supplier Advantage
Chengdu Biopurify Phytochemicals Ltd. 		58
GL Biochem(Binhai) Ltd. 		58
AFINE CHEMICALS LIMITED 		58
BOC Sciences 		58
Nextpeptide Inc 		58
TargetMol Chemicals Inc. 		58
Wuhan Han Sheng New Material Technology Co.，Ltd 		58
Wuhan BJM Pharm Inc 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58

42438-90-4(L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID)Related Search:

BOC-D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID FMOC-D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID 1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE (S)-1,2,3,4-Tetrahydronorharman-3-carboxylic acid, N2-FMOC protected,FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID BOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
(1S,3S)-2,3,4,9-TETRAHYDRO-1-METHYL-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID (1S,3S)-1-ETHYL-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID BOC-TPI(FOR)-OH L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID FMOC-DL-6-METHOXY-1,2,3,4-TETRAHYDRONORHARMAN-1-CARBOXYLIC ACID
BOC-DL-6-METHOXY-1,2,3,4-TETRAHYDRONORHARMAN-1-CARBOXYLIC ACID D-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID CIS-1-(1,3-BENZODIOXOL-5-YL)-2-(CHLOROACETYL)-2,3,4,9-TETRAHYDRO-, 1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID METHYL ESTER 9-FORMYL-1,2,3,4-TETRAHYDRONORHARMAN-L-3-CARBOXYLIC ACID HYDROCHLORIDE 1,3,4,9-TETRAHYDRO-B-CARBOLINE-2-CARBOXYLIC ACID METHYL ESTER HCL
L-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE N-ALPHA-CARBOBENZOXY-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID H-TPI-OME

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L-TRYPTOLINE-3-CARBOXYLIC ACID H-TPI-OH H-THNH(3)-OH L-2,3,4-TETRAHYDRO-BETA-CARBOLINE-3-CARBOXYLIC ACID L-1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID 1,2,3,4-TETRAHYDRONORHARMAN-L-3-CARBOXYLIC ACID RARECHEM BK PT 0088 (S)-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID L-1,2,3,4-tetrahydronorharmane-3-carboxylic acid L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carb 2,3,4,9-Tetrahydro-1H-β-carboline-3-carboxylic acid (3S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (3S)-1,2,3,4-Tetrahydro-β-carboline-3α-carboxylic acid (3S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3α-carboxylic acid (S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid Lycoperodine 1 (3S)-2,3,4,9-Tetrahydro-1H-beta-carboline-3-carboxylic acid L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid, L-Tryptoline-3-carboxylic acid, H-Tpi-OH, L-1,2,3,4-Tetrahydro-b-carboline-3-carboxylic acid (3S)-1,3,4,9-tetrahydro-$b-carbolin-2-ium-3-carboxylate (3S)-1,3,4,9-tetrahydropyrido[5,4-b]indol-2-ium-3-carboxylate (3S)-2,3,4,9-tetrahydro-1H-$b-carboline-3-carboxylic acid (3S)-2,3,4,9-tetrahydro-1H-pyrido[5,4-b]indole-3-carboxylic acid CYCLOMETHYLTRYPTOPHAN TCR (S)-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid (3S)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylic acid TNCA 4-b]indole-3-carboxylic acid 4-Tetrahydro-9H-pyrido[3 4-Tetrahydro-b-carboline-3-carboxylic acid 9-Tetrahydro-1H-beta-carboline-3-carboxylic acid L -CarL 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-, (3S)- L-1,2,3,4-Tetrahydro-β-carbolin-3-carboxylic acid TNCA >=98% (HPLC) Tryptophan Impurity M 42438-90-4 2438-90-4 C12H12NO2 Phenylalanine analogs and other aromatic alpha amino acids