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2-Bromo-4-fluoroaniline

2-Bromo-4-fluoroaniline structure

CAS No.: 1003-98-1

Chemical Name:: 2-Bromo-4-fluoroaniline

Synonyms: 2-BROMO-4-FLUORO-PHENYLAMINE;Bromofluoroaniline1;2-Bromo-4-fluoroanil;4-FLUORO-2-BROMOANILINE;2-BROMO-4-FLUOROANILINE;2-Bromo-4-fluoroaniline99%;2-Bromo-4-fluoroaniline >2-Bromo-4-fluoroaniline 99%;2-BROMO-4-FLUOROANILINE 98+%;2-Bromo-4-fluoroaniline, 95%

CBNumber:: CB1402890

Molecular Formula:: C6H5BrFN

Molecular Weight:: 190.01

MDL Number:: MFCD00042462

MOL File:: 1003-98-1.mol

MSDS File:: SDS

Last updated:2026-01-13 11:13:41

Product description	Number	Pack Size	Price
2-Bromo-4-fluoroaniline 97%	369055	5g	$25.2
2-Bromo-4-fluoroaniline >98.0%(GC)	B1829	5g	$30
2-Bromo-4-fluoroaniline >98.0%(GC)	B1829	25g	$95
2-Bromo-4-fluoroaniline	B678945	1g	$45
2-Bromo-4-fluoroaniline 99%	PC1397	100g	$48
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2-Bromo-4-fluoroaniline Properties

Melting point	41
Boiling point	221 °C (lit.)
Density	1.67 g/mL at 25 °C (lit.)
refractive index	n20/D 1.583(lit.)
Flash point	220 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Liquid
pka	2.60±0.10(Predicted)
color	Clear yellow-brown
Specific Gravity	1.670
BRN	2802562
InChI	InChI=1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2
InChIKey	YLMFXCIATJJKQL-UHFFFAOYSA-N
SMILES	C1(N)=CC=C(F)C=C1Br
CAS DataBase Reference	1003-98-1(CAS DataBase Reference)
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,T

Risk Statements

36/37/38

Safety Statements

26-37/39

RIDADR

UN2810

WGK Germany

Hazard Note

Toxic

HazardClass

6.1

PackingGroup

III

HS Code

29214200

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		1

2-Bromo-4-fluoroaniline price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	369055	2-Bromo-4-fluoroaniline 97%	1003-98-1	5g	$25.2	2023-01-07	Buy
TCI Chemical	B1829	2-Bromo-4-fluoroaniline >98.0%(GC)	1003-98-1	5g	$30	2025-07-31	Buy
TCI Chemical	B1829	2-Bromo-4-fluoroaniline >98.0%(GC)	1003-98-1	25g	$95	2025-07-31	Buy
TRC	B678945	2-Bromo-4-fluoroaniline	1003-98-1	1g	$45	2021-12-16	Buy
Apolloscientific	PC1397	2-Bromo-4-fluoroaniline 99%	1003-98-1	100g	$48	2021-12-16	Buy

Product number	Packaging	Price	Buy
369055	5g	$25.2	Buy
B1829	5g	$30	Buy
B1829	25g	$95	Buy
B678945	1g	$45	Buy
PC1397	100g	$48	Buy

2-Bromo-4-fluoroaniline Chemical Properties,Uses,Production

Uses

2-Bromo-4-fluoroaniline is an organic compound that is an aniline derivative. It is mainly used as an organic synthesis reagent in experimental research.

Chemical Properties

Clear yellow-brown liquid

General Description

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

Synthesis

371-40-4

1003-98-1

The general procedure for the synthesis of 2-bromo-4-fluoroaniline from 4-fluoroaniline was as follows: 200 mL of distilled N,N-dimethylformamide (DMF) and 4-fluoroaniline (8.64 mL, 58.13 mmol) were added to a two-necked flask equipped with a stirring device. N-bromosuccinimide (11.4 g, 63.95 mmol) dissolved in DMF was added slowly and dropwise with stirring. After completion of the reaction, extraction was carried out using dichloromethane (CH2Cl2). The product was purified by column chromatography (eluent ratio of ethyl acetate: n-hexane = 1:4), and the target product 2-bromo-4-fluoroaniline was finally obtained in 95% yield.

References

[1] Patent: KR2018/50795, 2018, A. Location in patent: Paragraph 0134; 0135; 0152-0154
[2] Tetrahedron Letters, 2000, vol. 41, # 13, p. 2083 - 2085
[3] Journal of the American Chemical Society, 2011, vol. 133, # 18, p. 6868 - 6870
[4] Chemistry - A European Journal, 2011, vol. 17, # 49, p. 13665 - 13669
[5] Tetrahedron Letters, 2014, vol. 55, # 38, p. 5338 - 5341

2-Bromo-4-fluoroaniline synthesis

Synthesis of 2-Bromo-4-fluoroaniline from 4-Fluoroaniline

2-Bromo-4-fluoroaniline Preparation Products And Raw materials

Raw materials

4-Fluoroaniline N,N-Dimethylformamide N-Bromosuccinimide

Preparation Products

5-Fluoro-2-methylindole 2-AMINO-5-FLUOROPHENYL BORONIC ACID PINACOL ESTER (2-Bromo-4-fluorophenyl)(methyl)sulfane 2-AMINO-5-FLUOROBENZENEBORONIC ACID 2-Bromo-4-fluoronitrobenzene

Methyl 8-bromo-6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate 4-Chloro-6-fluorocinnoline 4-fluoro-2-(2-phenylethynyl)phenylaMine tert-Butyl (2-bromo-4-fluorophenyl)carbamate

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2-Bromo-4-fluoroaniline Suppliers

Global( 483)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Kinso Technology Co., LTD.	+86-571-56950601; +8619857958369	sales@kinsopharma.com	China	48	58
Shanghai Quedan biology science and technology co., ltd	+86-13004146052	lnzc@quedan.com.cn	China	1022	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5242	58
Shandong Huisheng Import & Export Co., Ltd.	+86-13176845580	da@zhongda-biotech.com	China	232	58
Anhui Zhongda Biotechnology Co., Ltd	+8619956560829	justine@zhongda-biotech.com	China	286	58
Anhui Zhongda Biotechnology Co., Ltd	+8615689548120	linda@zhongda-biotech.com	China	193	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13676	58

Supplier	Advantage
Zhejiang Kinso Technology Co., LTD.	58
Shanghai Quedan biology science and technology co., ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Shandong Huisheng Import & Export Co., Ltd.	58
Anhui Zhongda Biotechnology Co., Ltd	58
Anhui Zhongda Biotechnology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58

View Lastest Price from 2-Bromo-4-fluoroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-04	2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE 1003-98-1	US $0.00 / kg	0.1kg	99.0%MIN	15000KG	Hangzhou ICH Biofarm Co., Ltd
2025-06-20	2-Bromo-4-fluoroaniline 1003-98-1	US $40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2025-05-26	2-Bromo-4-fluoroaniline 1003-98-1	US $5.00-2.00 / KG	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD

2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE
1003-98-1
US $0.00 / kg
99.0%MIN
Hangzhou ICH Biofarm Co., Ltd

2-Bromo-4-fluoroaniline
1003-98-1
US $40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

2-Bromo-4-fluoroaniline
1003-98-1
US $5.00-2.00 / KG
99%
Hebei Chuanghai Biotechnology Co,.LTD

2-Bromo-4-fluoroaniline Spectrum

2-Bromo-4-fluoroaniline(1003-98-1)MS 2-Bromo-4-fluoroaniline(1003-98-1)¹HNMR 2-Bromo-4-fluoroaniline(1003-98-1)¹³CNMR 2-Bromo-4-fluoroaniline(1003-98-1)IR1 2-Bromo-4-fluoroaniline(1003-98-1)Raman

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4-FLUORO-2-BROMOANILINE 2-BROMO-4-FLUOROANILINE 98+% Bromofluoroaniline1 2-Bromo-4-fluoroaniline 99% 2-Bromo-4-fluoroaniline99% 2-BROMO-4-FLUOROANILINE 2-Bromo-4-fluoroanil Benzenamine, 2-bromo-4-fluoro- 2 - broMine - 4 - fluoro aniline 2-Bromo-4-fluoroaniline > 2-Bromo-4-fluoroaniline ISO 9001：2015 REACH TIANFU-CHEM 2-Bromo-4-fluoroaniline 2-BROMO-4-FLUORO-PHENYLAMINE 4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-74-THIOSEMICARBAZIDE 2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE 2-Bromo-4-fluoroaniline, 95% 1003-98-1 C2 to C6 Amines Building Blocks Organic Building Blocks Nitrogen Compounds amine| alkyl Fluorine| alkyl bromide Pyridines Miscellaneous Anilines, Amides & Amines Bromine Compounds Fluorine Compounds Amines C2 to C6 Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene 1003-98-1