ChemicalBook >> CAS DataBase List >>6-Aminopenicillanic acid
6-Aminopenicillanic acid
- CAS No.
- 551-16-6
- Chemical Name:
- 6-Aminopenicillanic acid
- Synonyms
- 6-APA;6-amino penicillanic acid(6-APA);6-Amino;Flucloxacillin EP Impurity C;AMoxicillin Related CoMpound A;6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;Amoxicillin Related Compound A (15 mg) ((2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid);penin;6-aps;penicin
- CBNumber:
- CB1410046
- Molecular Formula:
- C8H12N2O3S
- Molecular Weight:
- 216.26
- MDL Number:
- MFCD00005176
- MOL File:
- 551-16-6.mol
Last updated:2024-04-09 22:15:29
| Melting point | 198-200 °C (dec.)(lit.) |
|---|---|
| alpha | 276.3 º (c=1.2, 0.1N HCl 22 ºC) |
| Boiling point | 460.2±45.0 °C(Predicted) |
| Density | 1.3418 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | 2-8°C |
| solubility | 2.46g/l |
| form | Fine Powder |
| pka | pKa 2.3 (Uncertain) |
| color | White to cream |
| PH | 3.4 (100g/l, H2O) |
| optical activity | [α]22/D +276.3°, c = 1.2 in 0.1 M HCl |
| Water Solubility | Soluble in water and hydrochoric acid. |
| Merck | 14,458 |
| BRN | 15080 |
| Stability | Light sensitive |
| InChIKey | NGHVIOIJCVXTGV-SDKNWNMFSA-N |
| LogP | -3.87 at 22.5℃ |
| CAS DataBase Reference | 551-16-6(CAS DataBase Reference) |
| FDA UNII | QR0C4R7XVN |
| EPA Substance Registry System | 6-Aminopenicillanic acid (551-16-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 42/43 | |||||||||
| Safety Statements | 22-36/37-45-37-24-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | XH8225000 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
6-Aminopenicillanic acid price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2188 | Amoxicillin Related Compound A | 551-16-6 | 50MG | $534 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1031514 | Amoxicillin Related Compound A United States Pharmacopeia (USP) Reference Standard | 551-16-6 | 15mg | $1490 | 2024-03-01 | Buy |
| Sigma-Aldrich | 07307 | (+)-6-Aminopenicillanic acid analytical standard | 551-16-6 | 100mg | $80.4 | 2024-03-01 | Buy |
| TCI Chemical | A0800 | 6-Aminopenicillanic Acid >98.0%(HPLC) | 551-16-6 | 5g | $18 | 2024-03-01 | Buy |
| TCI Chemical | A0800 | 6-Aminopenicillanic Acid >98.0%(HPLC) | 551-16-6 | 25g | $53 | 2024-03-01 | Buy |
6-Aminopenicillanic acid Chemical Properties,Uses,Production
Chemical Properties
WHITE TO CREAM FINE POWDER
Uses
6-Aminopenicillanic acid is the basic unit in penicillin?s, which is obtained from the fermentation brew of the Penicillium mold. It acts as a starting material for the preparation of many semisynthetic penicillins. Further, it serves as apharmaceutical intermediate. In addition to this, it is used in antibiotics research and experimental application.
Uses
(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
Definition
ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.
General Description
Chemical structure: ?-lactam
Flammability and Explosibility
Non flammable
Safety Profile
Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Purification Methods
This acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]
6-Aminopenicillanic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of3
Global( 514)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12452 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 | sales@ichemie.com | China | 985 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9353 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
View Lastest Price from 6-Aminopenicillanic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-10 | Piperacillin Impurity H(EP)
551-16-6
|
US $0.00-0.00 / mg | 10mg | 90%+ | 500mg | Guangzhou PI PI BIOTECH INC | |
 |
2024-04-10 | Ampicillin Impurity A
551-16-6
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC | |
 |
2024-04-09 | Aminopenicillanic Acid
551-16-6
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. |
-
- Piperacillin Impurity H(EP)
551-16-6
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
-
- Ampicillin Impurity A
551-16-6
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
-
- Aminopenicillanic Acid
551-16-6
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
551-16-6(6-Aminopenicillanic acid)Related Search:
6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
(+)-6-AMINOPENICILLANIC ACID
6-AMINOPENICILLANIC ACID
6-AMINO PENICILLINIC ACID
7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID
(25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
(2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO-[3.2.0]HEPTANE-2-CARBOXYLIC ACID
aminopenicillanicacid
penicin
penin
phenacyl6-aminopenicillinate
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]-
6-Aminopenicillanic acid;6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA
6-Aminopenicillanicacid,98%
6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
6-Aminopenicillansure
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]
6-AMINOPENICILLANIC ACID 99%
(2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98%
(2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid
AMoxicillin IMpurity A (SulbactaM IMpurity B)
Piperacillin IMpurity H
Amoxicillin EP Impurity A
(+)-6-Aminopenicillanic acid, >=99.0%
Penicillan intermediate: penicillan core
6-Aminopenicillanic acid for synthesis
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-APA
6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-amino-3,3-dimethyl-7-oxo
5alpha,6beta)]-[2s-(2alpha
6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid
6-aps
6-APA, (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
(2S,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
(2β,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid
(6R)-6-Aminopenicillanic acid
6-Aminopenicillanic acid,96%
6-AMinopenicillanic acid, 96% 25GR
[2S-(2α,5α,6β)]-6-AMino-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
NSC 50071
4-AMino-5-nitroso-2,6-pyriMidinediol-13C2
5-Nitroso-6-aMinouracil-13C2
6-AMino-5-nitroso-2,4(1H,3H)-pyriMidinedione-13C2
6-AMino-5-nitroso-2,4-pyriMidinediol-13C2
6-AMino-5-nitroso-22,4(1H,3H)-pyriMidinedione-13C2
6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
6-APA
6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1
(+)-6-Aminopenicillanic acid,(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-APA
(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (6-Aminopenicillanic Acid)
SulbactaM IMpurity B (AMoxicillin IMpurity A)
Amoxicillin EP Impurity A(Sulbactam EP Impurity B)
Sulbactam impurity B
6-aminopenicilanic acid(6-APA)
Cloxacillin Impurity 3(Cloxacillin EP Impurity C)
Dicloxacillin Impurity 3(Dicloxacillin EP Impurity C)
Flucloxacillin Impurity 3(Flucloxacillin EP Impurity C)
Piperacillin Impurity 8(EP Impurity H)
Sulbactam Impurity 2(Sulbactam EP Impurity B)