ChemicalBook >> CAS DataBase List >>6-AZAURIDINE

6-AZAURIDINE

6-AZAURIDINE structure

CAS No.: 54-25-1

Chemical Name:: 6-AZAURIDINE

Synonyms: azauridine;6-azuridine;azur;6-azur;nsc32074;AZURIDINE;Aids008706;Aids-008706;6-AZAURIDINE;ribo-azuracil

CBNumber:: CB1413830

Molecular Formula:: C8H11N3O6

Molecular Weight:: 245.19

MDL Number:: MFCD00006472

MOL File:: 54-25-1.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:39

Request For Quotation

6-AZAURIDINE Properties

Melting point	157-159 °C(lit.)
Boiling point	388.15°C (rough estimate)
Density	1.4866 (rough estimate)
refractive index	1.7950 (estimate)
storage temp.	2-8°C
solubility	DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water
form	Powder
pka	6.70(at 25℃)
color	White
Water Solubility	It is soluble in water.
Merck	14,904
Stability	Hygroscopic
InChIKey	WYXSYVWAUAUWLD-YGWZKZRUSA-N
CAS DataBase Reference	54-25-1(CAS DataBase Reference)
FDA UNII	7BVB29RCPR
NCI Drug Dictionary	6-azauridine

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Warning
Hazard statements	H302+H312+H332-H351
Precautionary statements	P201-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
Hazard Codes	Xn
Risk Statements	20/21/22-40
Safety Statements	22-36
WGK Germany	3
RTECS	XY8575000
HS Code	29349990
Toxicity	LD50 oral in quail: > 316mg/kg

6-AZAURIDINE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A1882	6-Azauridine	54-25-1	1g	$86.1	2024-03-01	Buy
Sigma-Aldrich	A1882	6-Azauridine	54-25-1	5g	$481	2024-03-01	Buy
TCI Chemical	A0559	6-Azauridine >99.0%(HPLC)	54-25-1	10mg	$30	2024-03-01	Buy
Alfa Aesar	J61309	6-Azauridine	54-25-1	1g	$118.65	2024-03-01	Buy
Alfa Aesar	J61309	6-Azauridine	54-25-1	5g	$471.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
A1882	1g	$86.1	Buy
A1882	5g	$481	Buy
A0559	10mg	$30	Buy
J61309	1g	$118.65	Buy
J61309	5g	$471.65	Buy

6-AZAURIDINE Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

6-Azauridine (AzUrd) blocks the conversion of orotic acid into UMP and it is used in antiviral studies.

Uses

6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.

Uses

Research on cell formation and cancer.

Definition

ChEBI: 6-azauridine is a N-glycosyl-1,2,4-triazine. It has a role as an antineoplastic agent, an antimetabolite and a drug metabolite.

General Description

6-Azauridine is a pyrimidine nucleoside analog.

Biochem/physiol Actions

6-azauridine is a prodrug, upon conversion to 6-aza-UMP, inhibits uridine monophosphate synthase (UMPS). It is a broad spectrum anti-metabolite. It interferes with pyrimidine biosynthesis and affects the cellular nucleic acid levels. It is considered as a antineoplastic metabolite. It inhibits RNA viruses like chikungunya virus, semliki forest virus, and human coronavirus. It significantly inhibits the growth of Cryptosporidium parasites.

6-AZAURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

6-AZAURIDINE Suppliers

Global( 111)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10027	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49999	58

Supplier	Advantage
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
NewCan Biotech Limited	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from 6-AZAURIDINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	6-AZAURIDINE 54-25-1	US $1.00 / kg	1kg	95%-99%	as request	Career Henan Chemical Co
	2019-07-06	6-AZAURIDINE 54-25-1	US $1.00 / kg	1kg	95%-99%	100kg	Career Henan Chemical Co

6-AZAURIDINE
54-25-1
US $1.00 / kg
95%-99%
Career Henan Chemical Co

6-AZAURIDINE
54-25-1
US $1.00 / kg
95%-99%
Career Henan Chemical Co

6-AZAURIDINE Spectrum

6-AZAURIDINE(54-25-1)MS 6-AZAURIDINE(54-25-1)¹HNMR 6-AZAURIDINE(54-25-1)IR1 6-AZAURIDINE(54-25-1)Raman

54-25-1(6-AZAURIDINE)Related Search:

6-AZAURIDINE 2',3',5'-TRIACETATE Semicarbazide 2-Hydroxyethylhydrazine (Hydroxymethyl)urea 2-HYDROXYETHYLUREA

6-AZAURIDINE 3-Methylamino-1,2-propanediol 1,3-DIETHYLUREA 6-AZAURACIL N-Butylurea

6-Azauracil 6-AZA-2'-DEOXYURIDINE 6-AZAURIDINE-5'-MONOPHOSPHATE,6-Azauridine 5'-phosphoric acid N-ETHYL-N-FORMYLHYDRAZINE 5-Methyl-2'-deoxy-6-azauridine

2-THIO-6-AZAURIDINE 6-azauridine 5'-triphosphate 5-Azauridine

1of4

azur nsc32074 ribo-azuracil 2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5-diol 2-β-d-ribofuranosyl-1,2,4-triazine-3,5(2h,4h)-dione AZURIDINE TRIAZINE-3,5-DIONE,2-BETA-D-RIBOFURANOSYL- 6-Azauracil riboside, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione Ribo-Azauracil 1,2,4-Triazine-3,5(2H,4H)-dione, 2-.beta.-D-ribofuranosyl- Aids008706 Aids-008706 2-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione 1,2,4-Triazine-3,5(2H,4H)-dione,2-b-D-ribofuranosyl- Rib-Azauracil 6-AZAURIDINE CRYSTALLINE 6-AZA-2,4-DIHYDROXYPYRIMIDINE RIBOSIDE 6-AZAURIDINE MONOHYDRATE 6-AZAURACIL RIBOSIDE 6-AZAURACIL RIBOSIDE MONOHYDRATE 6-AZAURIDINE 2-BETA-D-RIBOFURANOSYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE AZAURIDINE, 6- 2-beta-d-ribofuranosyl-1,2,4-triazin-3,5(2h,4h)-dion 2-beta-d-ribofuranosyl-as-triazine-3,5(2h,4h)-dione 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazineriboside 4h)-dione,2-beta-d-ribofuranosyl-as-triazine-5(2h 4-triazine-3,5(2h,4h)-dione,2-beta-d-ribofuranosyl-2 6-azauracil1-riboside 6-azauracil-beta-d-riboside 6-azauracilribosid 6-azur 6-Azauridine> 1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl- 6-AZAURIDINE USP/EP/BP 6-Azauridine, antimetabolic antineoplastic agent 6-azuridine azauridine 1-(beta-D-Ribofuranosyl)-6-azauracil 54-25-1 C8H11N3O6H2O C8H11N3O6 Biochemicals and Reagents BioChemical Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs Biochemistry Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents Antibiotic Explorer Pyridines, Pyrimidines, Purines and Pteredines