ChemicalBook >> CAS DataBase List >>3-Indoleacetonitrile

3-Indoleacetonitrile

CAS No.
771-51-7
Chemical Name:
3-Indoleacetonitrile
Synonyms
IAN;3-ICN;usafcb-29;NSC 523272;USAF cb-29;3-Indolyl-acet;Indoleacetonitrile;Indolylacetonitril;3-Indolacetonitrile;Indolylacetonitrile
CBNumber:
CB1423479
Molecular Formula:
C10H8N2
Molecular Weight:
156.18
MDL Number:
MFCD00005628
MOL File:
771-51-7.mol
MSDS File:
SDS

3-Indoleacetonitrile Properties

Melting point 33-36 °C(lit.)
Boiling point 157-160 °C0.2 mm Hg(lit.)
Density 1.1566 (rough estimate)
refractive index 1.6085-1.6105
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, DMSO (Slightly), Methanol (Slightly)
pka 16.32±0.30(Predicted)
form Liquid
color Clear colorless to yellow
BRN 125488
InChIKey DMCPFOBLJMLSNX-UHFFFAOYSA-N
CAS DataBase Reference 771-51-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII AG97OFW8JW
NIST Chemistry Reference 1H-Indole-3-acetonitrile(771-51-7)
EPA Substance Registry System 1H-Indole-3-acetonitrile (771-51-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS07
Signal word  Danger
Hazard statements  H301+H311+H331-H302-H312-H332
Precautionary statements  P280h-P301+P312a-P304+P340-P321-P501a-P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P403+P233-P405-P501
Hazard Codes  Xn,Xi
Risk Statements  20/21/22
Safety Statements  36/37
RIDADR  3276
WGK Germany  3
RTECS  AM0700000
Hazard Note  Irritant
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29339990
NFPA 704
1
2 0

3-Indoleacetonitrile price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 129453 3-Indoleacetonitrile 98% 771-51-7 5g $56.9 2022-05-15 Buy
Sigma-Aldrich 129453 3-Indoleacetonitrile 98% 771-51-7 25g $142 2022-05-15 Buy
TCI Chemical I0024 3-Indoleacetonitrile >98.0%(GC) 771-51-7 1g $44 2022-04-27 Buy
TCI Chemical I0024 3-Indoleacetonitrile >98.0%(GC) 771-51-7 25g $306 2022-04-27 Buy
TRC I577355 Indole-3-acetonitrile 771-51-7 50g $250 2021-12-16 Buy
Product number Packaging Price Buy
129453 5g $56.9 Buy
129453 25g $142 Buy
I0024 1g $44 Buy
I0024 25g $306 Buy
I577355 50g $250 Buy

3-Indoleacetonitrile Chemical Properties,Uses,Production

Chemical Properties

clear yellow-brown to brown liquid after melting

Uses

Reactant for preparation of:

  • Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Histone deacetylase inhibitors
  • Potential kinase inhibitors
  • Kv7/KCNQ potassium channel activators
  • Kinesin-Specific MKLP-2 Inhibitor
  • Pesticides
  • Potential PET cancer imaging agents
  • Agonists of the Farnesoid X Receptor (FXR) as atherosclerosis treatment
  • Butyrylcholinesterase inhibitors
  • Necroptosis inhibitors

Definition

ChEBI: A nitrile that is acetonitrile where one of the methyl hydrogens is substituted by a 1H-indol-3-yl group.

Synthesis Reference(s)

Canadian Journal of Chemistry, 39, p. 1340, 1961 DOI: 10.1139/v61-169
Journal of the American Chemical Society, 75, p. 3589, 1953 DOI: 10.1021/ja01110a506

General Description

3-Indoleacetonitrile (Indolylacetonitrile) is a light-induced auxin-inhibitory substance that is isolated from light-grown cabbage (Brassica olearea L.) shoots. It inhibits the biofilm formation of both E. coli O157:H7 and P. aeruginosa without affecting its growth.

87-52-5
143-33-9
771-51-7
Synthesis of 3-Indoleacetonitrile from Gramine and Sodium cyanide
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Henan DaKen Chemical CO.,LTD.
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TargetMol Chemicals Inc.
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View Lastest Price from 3-Indoleacetonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2021-08-28 3-Indoleacetonitrile
771-51-7
US $9.85 / KG 1KG 99% 10 m Hebei Guanlang Biotechnology Co., Ltd.
2021-07-20 3-Indoleacetonitrile
771-51-7
US $0.00-0.00 / KG 5mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2020-06-02 Indole-3-acetonitrile in stock Factory
771-51-7
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 largest production capacity Factory Chemwill Asia Co.,Ltd.
3-Indolyl-acet Indole-3-acetonitrile,98% NSC 523272 INDOLYL-3-ACETONITRILE INDOLE-3-ACETONITRILE BETA-INDOLYLACETONITRILE 2-(1H-INDOL-3-YL)ACETONITRILE (1H-INDOL-3-YL)-ACETONITRILE 3-INDOLEACETONITRILE 3-INDOLYLACETONITRILE 3-((dimethylamino)methgl)-indole IAN 3-ICN INDOLE-3-ACETONITRILE(IAN) 3-Indolylacetonitrile,98% 3-Indoleacetonitrile,(3-Indolyl)acetonitrile 3-(Cyanomethyl)-1H-indole INDOLE-3-ACETONITRILE FOR SYNTHESIS Indole-3-acetonitrile (8CI) 3-Indoleacetonitrile 98% 1h-indole-3-acetonitrile 3-(Cyanomethyl)indole 3-Indolacetonitrile 3-indolyl-acetonitril Acetonitrile, 3-indolyl- beta-Indoleacetonitrile Indoleacetonitrile Indolylacetonitril Indolylacetonitrile USAF cb-29 usafcb-29 3-INDOLYLACETONITRILE PESTANAL, 250 MG 1H-INDOLE-3-ACETONITRILE:3-INDOLEACETONITRILE indol-3-ylacetonitrile Indole-3-acetonitrile in stock Factory (1H-Indol-3-yl)acetonitrile 98% 3-Indoleacetonitrile> Indole-3-acetonitrile 3-Indolylacetonitrile Indoleacetonitrile Indolylacetonitrile 771-51-7 C10H8N2 3-Indoleacetonitrile Indole-3-Acetonitrile pure, 99% 771-51-7 771-57-7 711-5-7 Heterocyclic Building Blocks Building Blocks Simple Indoles Indoles Indole Indoles Simple Indoles Pyrroles & Indoles indole derivative Indoles and derivatives Pyrroles & Indoles