METHYL (1-TRIMETHYLSILYL)ACRYLATE
- CAS No.
- 18269-31-3
- Chemical Name:
- METHYL (1-TRIMETHYLSILYL)ACRYLATE
- Synonyms
- Methyl 2-Trimethylsilylacrylate;METHYL (1-TRIMETHYLSILYL)ACRYLATE;2-Propenoic acid, 2-(trimethylsilyl)-, methyl ester
- CBNumber:
- CB1424461
- Molecular Formula:
- C7H14O2Si
- Molecular Weight:
- 158.27
- MDL Number:
- MFCD00466989
- MOL File:
- 18269-31-3.mol
METHYL (1-TRIMETHYLSILYL)ACRYLATE Chemical Properties,Uses,Production
Physical properties
bp 75 °C/50 mmHg, 152 °C/690 mmHg.
Uses
Methyl 2-Trimethylsilylacrylate is widely used as reactive, α-silyl Michael acceptor for conjugate addition of carbanions, enolate anions, organolithium reagents, and Grignard reagents; affords 3-cyclopentenecarboxylates and cyclohexanecarboxylates by [3 + 2] and [4 + 2] annulation methods; provides α-silyl esters and vinylsilanes by organolithium conjugate additions.
Preparation
Methyl 2-Trimethylsilylacrylate is prepared by the reaction of (E)-2- (trimethylsilyl)vinyllithium with methyl chloroformate or by carbonation of the corresponding Grignard reagent prepared from (1-bromovinyl)trimethylsilane, giving 2-trimethylsilylacrylic acid. The methyl ester is prepared from the acid by direct esterification with absolute methanol in the presence of mineral acid, by reaction with diazomethane at low temperature, or by treatment with BF3·MeOH complex.
METHYL (1-TRIMETHYLSILYL)ACRYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL (1-TRIMETHYLSILYL)ACRYLATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chempro Tech Co., Ltd. | -- | China | 6803 | 60 | |
| Guangzhou WeiBo Chemical Co., Ltd. | -- | weibochem@163.com | China | 6187 | 67 |
| 3B Scientific Corporation | -- | sales@3bsc.com | United States | 6744 | 47 |
| Fluorochem Ltd | -- | vernam@fluorochem.co.uk | United Kingdom | 6383 | 65 |
| Fluorochem Ltd. | -- | enquiries@fluorochem.co.uk | United Kingdom | 6406 | 74 |
| Supplier | Advantage |
|---|---|
| Chempro Tech Co., Ltd. | 60 |
| Guangzhou WeiBo Chemical Co., Ltd. | 67 |
| 3B Scientific Corporation | 47 |
| Fluorochem Ltd | 65 |
| Fluorochem Ltd. | 74 |