ChemicalBook >> CAS DataBase List >>2,4-DIETHYLPYRIDINE DICARBOXYLATE

2,4-DIETHYLPYRIDINE DICARBOXYLATE

CAS No.
41438-38-4
Chemical Name:
2,4-DIETHYLPYRIDINE DICARBOXYLATE
Synonyms
2,4-DPD;Ai3-17897;Diethyl-2,4-pdc;2,4-Pdc diethyl ester;2,4-Pyridinedicarboxylic;DIETHYL 2,4-PYRIDINECARBOXYLATE;2,4-DIETHYLPYRIDINE DICARBOXYLATE;Diethyl 2,4-pyridinedicarboxylate;diethyl pyridine-2,4-dicarboxylate;diethyl 2,4-pyridinedicarboxylic acid
CBNumber:
CB1454066
Molecular Formula:
C11H13NO4
Molecular Weight:
223.23
MDL Number:
MFCD00152168
MOL File:
41438-38-4.mol
Last updated:2023-06-08 17:06:33

2,4-DIETHYLPYRIDINE DICARBOXYLATE Properties

Melting point 31 °C
Boiling point 330.9±22.0 °C(Predicted)
Density 1.165±0.06 g/cm3(Predicted)
vapor pressure 0.022Pa at 25℃
storage temp. 2-8°C
solubility ≤50mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide
pka -0.69±0.10(Predicted)
form Crystalline
color White to Almost white
LogP 1.92 at 20℃ and pH7.82
Surface tension 56.3mN/m at 1g/L and 19.7℃
CAS DataBase Reference 41438-38-4
FDA UNII 4SN4572M5S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2933.39.9200
NFPA 704
3
2 0

2,4-DIETHYLPYRIDINE DICARBOXYLATE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5518 Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) 41438-38-4 200mg $62 2024-03-01 Buy
TCI Chemical D5518 Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) 41438-38-4 1g $186 2024-03-01 Buy
Cayman Chemical 71200 2,4-DPD ≥98% 41438-38-4 10mg $19 2024-03-01 Buy
Cayman Chemical 71200 2,4-DPD ≥98% 41438-38-4 25mg $41 2024-03-01 Buy
Cayman Chemical 71200 2,4-DPD ≥98% 41438-38-4 50mg $78 2024-03-01 Buy
Product number Packaging Price Buy
D5518 200mg $62 Buy
D5518 1g $186 Buy
71200 10mg $19 Buy
71200 25mg $41 Buy
71200 50mg $78 Buy

2,4-DIETHYLPYRIDINE DICARBOXYLATE Chemical Properties,Uses,Production

Biological Activity

2,4-dpd is a cell permeable, competitive inhibitor of the oxygen-sensing enzyme hif-α prolyl hydroxylase (hif-ph) [1].hypoxia-inducible factor (hif) is a transcription factor with a key role in cellular responses to hypoxia in a variety of organisms. the hif system plays an important role in angiogenesis, erythropoiesis, energy utilization, glucose/energy metabolism, tumour development, and ischaemic/hypoxic disease. genetic or pharmacological inactivation of the hif hydroxylases results in a constitutive activation of the hif pathway with little or even absent regulation by oxygen remaining. the oxygen-sensing enzyme hif-α prolyl hydroxylase catalyzes hydroxylation of specific prolyl and asparaginyl residues in the regulatory hif-α subunits [2].exposure to 2,4-dpd limited prolyl 4-hydroxylase activity in c. elegans., where their esters are hydrolyzed to form competitors of a -ketoglutarate. 2,4-dpd showed dramatic effects among the progeny. when exposed to a high level of 2,4-dpd (2.7 mm), all progeny died regardless of genotype of c. elegans. the dead embryos arrested at the twofold stage [1].

References

[1] friedman l, higgin j j, moulder g, et al. prolyl 4-hydroxylase is required for viability and morphogenesis in caenorhabditis elegans[j]. proceedings of the national academy of sciences, 2000, 97(9): 4736-4741.
[2] schofield c j, ratcliffe p j. signalling hypoxia by hif hydroxylases[j]. biochemical and biophysical research communications, 2005, 338(1): 617-626.

2,4-DIETHYLPYRIDINE DICARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 79)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30256 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9589 58
Wuhan Fortuna Chemical Co., Ltd
+86-27-59207850 +86-13986145403 info@fortunachem.com China 5981 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9427 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Aceschem Inc.
+1-817863-6948 +1-(817)863-6948 sales@aceschem.com United States 19639 58

View Lastest Price from 2,4-DIETHYLPYRIDINE DICARBOXYLATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diethyl 2,4-Pyridinedicarboxylate pictures 2022-07-30 Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
US $0.00-0.00 / g 1g 98.0% 1kg/month WUHAN FORTUNA CHEMICAL CO., LTD
DIETHYL 2,4-PYRIDINECARBOXYLATE Diethyl 2,4-pyridinedicarboxylate 2,4-Pyridinedicarboxylic acid, diethyl ester Pyridine-2,4-Dicarboxylic Acid Diethyl Ester 2,4-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER 2,4-DPD 2,4-DIETHYLPYRIDINE DICARBOXYLATE 2,4-Pyridinedicarboxylic 2,4-pyridinedicarboxylicacid,ethylester diethyl 2,4-pyridinedicarboxylic acid 2,4-Pdc diethyl ester Ai3-17897 Diethyl-2,4-pdc diethyl pyridine-2,4-dicarboxylate 2,4-pyridine dicarboxylic acid 2,4-diethyl ester 2,4-DIETHYL PYRIDINE-2,4-DICARBOXYLATE pyridine-2,4-dicarboxylic acid diethyl ester Collagen formation,Diethyl ester,Chick-embryo calvaria,2,4DPD,inhibit,Inhibitor,Prolyl hydroxylation,2,4 DPD,Procollagen 41438-38-4 Pyridines, Pyrimidines, Purines and Pteredines