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GM 1489

GM 1489 Structure
GM 1489 structure
CAS No.
171347-75-4
Chemical Name:
GM 1489
Synonyms
(3R)-3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-hexanoicacid;Hexanoic acid, 3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-, (3R)-
CBNumber:
CB14666490
Molecular Formula:
C27H33N3O4
Molecular Weight:
463.57
MDL Number:
MOL File:
171347-75-4.mol
Last updated:2023-05-21 10:59:17
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GM 1489 Properties

Boiling point 795.4±60.0 °C(Predicted)
Density 1.203±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form A crystalline solid
pka 4.71±0.10(Predicted)

GM 1489 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24313 GM 1489 ≥98% 171347-75-4 1mg $73 2024-03-01 Buy
Cayman Chemical 24313 GM 1489 ≥98% 171347-75-4 5mg $341 2024-03-01 Buy
Product number Packaging Price Buy
24313 1mg $73 Buy
24313 5mg $341 Buy

GM 1489 Chemical Properties,Uses,Production

Description

GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2''-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression as well as cell invasion in AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells. Topical administration of GM 1489 (100 μg) inhibits increases in ear thickness and epidermal hyperplasia induced by phorbol 12-myristate 13-acetate (TPA; ) and phorbol dibutyrate (PdiBu) in mice.

GM 1489 Preparation Products And Raw materials

Raw materials

Preparation Products

GM 1489 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24023 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5021 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Hexanoic acid, 3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-, (3R)- (3R)-3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-hexanoicacid 171347-75-4