ChemicalBook
Chinese Japanese Germany Korea

Enalapril maleate

Enalapril maleate
Enalapril maleate structure
CAS No.
76095-16-4
Chemical Name:
Enalapril maleate
Synonyms
BQL;Pres;Ednyt;Envas;Nuril;Xanef;MK-421;Enaloc;Enaril;Hytrol
CBNumber:
CB1467853
Molecular Formula:
C24H32N2O9
Formula Weight:
492.52
MOL File:
76095-16-4.mol

Enalapril maleate Properties

Melting point:
143-144,5°C
Boiling point:
0°C
alpha 
D25 -42.2° (c = 1 in methanol)
Flash point:
0°C
storage temp. 
-20°C Freezer
solubility 
methanol: ≥50 mg/mL, clear, colorless to yellow
form 
powder
pka
pKa1 3.0; pKa2 (25°) 5.4
color 
white to off-white
Water Solubility 
Soluble in water, methanol, and ethanol.
λmax
208nm(MeOH)(lit.)
Merck 
14,3567
CAS DataBase Reference
76095-16-4(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-62-63
Safety Statements  22-24/25-36/37-26
RIDADR  3077
WGK Germany  2
RTECS  TW3666000
HS Code  29339900
Hazardous Substances Data 76095-16-4(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.

Enalapril maleate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16616 Enalapril maleate salt analytical standard 76095-16-4 50mg $57.7 2018-11-13 Buy
Sigma-Aldrich 1235300 Enalapril maleate United States Pharmacopeia (USP) Reference Standard 76095-16-4 200mg $348 2018-11-13 Buy
TCI Chemical E1010 Enalapril Maleate >98.0%(HPLC)(T) 76095-16-4 1g $60 2018-11-22 Buy
TCI Chemical E1010 Enalapril Maleate >98.0%(HPLC)(T) 76095-16-4 5g $207 2018-11-22 Buy
Alfa Aesar J63932 Enalapril maleate salt 76095-16-4 5g $217 2018-11-13 Buy

Enalapril maleate Chemical Properties,Uses,Production

Description

Enalapril maleate is the second angiotensin converting enzyme inhibitor to reach the marketplace. Like captopril, the first entry in this area, enalapril is useful in the treatment of hypertension and congestive heart failure. It has a longer effective half-life than captopril, allowing once or twice-daily dosing, and appears to have a somewhat lower incidence of side effects.

Chemical Properties

White to Off-White Crystalline Powder

Originator

Merck (USA)

Uses

An antihypertensive. An angiotensin-converting enzyme (ACE) inhibitor.

Uses

sunscreen

Definition

ChEBI: The maleic acid salt of enalapril. It contains one molecule of maleic acid for each molecule of enalapril. Following oral administration, the ethyl ester group of enalapril is hydrolysed to afford the corresponding carboxylic acid, enalaprilat, an angioten in-converting enzyme (ACE) inhibitor. Enalapril is thus a prodrug for enalaprilat (which, unlike enalapril, is not absorbed by mouth), and its maleate is used in the treatment of hypertension and heart failure, for reduction of proteinuria and renal diseas in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients.

brand name

RENITEN

General Description

Enalapril maleate, 1-[N[(S)-1-carboxy-3-phenylpropyl]-L-alanyl]-L-proline 1 -ethyl estermaleate (Vasotec), is a long-acting ACE inhibitor. It requiresactivation by hydrolysis of its ethyl ester to form thediacid enalaprilat. Enalapril is devoid of the side effects ofrash and loss of taste seen with captopril. These side effectsare similar to those of the mercapto-containing drugpenicillamine. The absence of the thiol group in enalaprilmaleate may free it from these side effects. The half-life is11 hours.

Enalapril maleate Preparation Products And Raw materials

Raw materials

Preparation Products


Enalapril maleate Suppliers

Global( 281)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Jinan Jianfeng Chemical Co., Ltd
15562555968
info@pharmachemm.com CHINA 617 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8430 58
Jinan Tenglong Chemical Co.,Ltd
Whatsapp:+8615563263311 Skype:live:smions7080
smions7080@gmail.com CHINA 770 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58

View Lastest Price from Enalapril maleate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Enalapril maleate
76095-16-4
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-04-11 Enalapril maleate
76095-16-4
US $1.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.

76095-16-4(Enalapril maleate )Related Search:


Copyright 2017 © ChemicalBook. All rights reserved