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4-DiMethylaMino Antipyrine

4-DiMethylaMino Antipyrine
4-DiMethylaMino Antipyrine structure
CAS No.
58-15-1
Chemical Name:
4-DiMethylaMino Antipyrine
Synonyms
Febron;Dereuma;Dipirin;Dipyrin;Hyparon;Pirazon;Piridol;Amidozon;Amidofen;Dipyrine
CBNumber:
CB1476086
Molecular Formula:
C13H17N3O
Formula Weight:
231.29
MOL File:
58-15-1.mol

4-DiMethylaMino Antipyrine Properties

Melting point:
107-109 °C(lit.)
Boiling point:
373.38°C (rough estimate)
Density 
1.0744 (rough estimate)
refractive index 
1.6140 (estimate)
storage temp. 
Refrigerator
pka
pKa 5.0 (Uncertain)
form 
Crystalline Powder, Crystals and/or Chunks
color 
Off-white to brownish
Water Solubility 
5.55 g/100 mL
Sensitive 
Air & Light Sensitive
Merck 
14,474
Stability:
Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive. Degrades under the action of mild oxidizing agents in the presence of moisture or water.
InChIKey
RMMXTBMQSGEXHJ-UHFFFAOYSA-N
CAS DataBase Reference
58-15-1(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
01704YP3MO
ATC code
N02BB03
NIST Chemistry Reference
Aminopyrine(58-15-1)
EPA Substance Registry System
Aminopyrine (58-15-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335-H302
Precautionary statements  P261-P301+P310-P305+P351+P338-P264-P270-P301+P312a-P330-P501a
Hazard Codes  Xn
Risk Statements  22-36/37/38-21/22
Safety Statements  26-36-36/37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  CD2625000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29331190
Toxicity LD50 orally in rats: 1.7 g/kg (Hart)
NFPA 704
1
2 1

4-DiMethylaMino Antipyrine price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D8015 4-Dimethylaminoantipyrine reactive nitrogen species scavenger 58-15-1 25g $68.9 2021-03-22 Buy
Sigma-Aldrich D8015 4-Dimethylaminoantipyrine reactive nitrogen species scavenger 58-15-1 100g $190 2021-03-22 Buy
Alfa Aesar B21436 4-(Dimethylamino)antipyrine, 98+% 58-15-1 250g $165 2020-06-24 Buy
Alfa Aesar B21436 4-(Dimethylamino)antipyrine, 98+% 58-15-1 50g $45.3 2020-06-24 Buy
Cayman Chemical 15770 Aminophenazone ≥98% 58-15-1 25g $59 2021-03-22 Buy

4-DiMethylaMino Antipyrine Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Antipyretic; analgesic.

Uses

Antipyretic;ACTH secretor

Definition

ChEBI: A pyrazolone that is 1,2-dihydro-3H-pyrazol-3-one substituted by a dimethylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It exhibits analgesic, anti-inflammatory, and antipyretic proper ies.

brand name

Adexogan;Agevis;Algimicin anttitermico;Amidazopen;Amidozen;Anoixal;Antigripina;Areumal;Axiston;Balbion;Barsedan;Baukal suppositories;Bayer 1387 p;Bronchisan;Brufaneuseol;Butapyrine;Capsyka dr knapf;Capysal;Chinopyrin;Cibalgin;Ciclazon;Clinit;Coffan;Compral;Cusayth;Demolpas;Dentigoa;Depiral c;Dexa escopyrin;Dha 51;Dialpyrin;Digisab;Dimametten;Dimopyrin;Diprin;Dolo-attirin;Dolo-optineural;Dolorphen;Dolovosano;Donobin;Duerin;Dysmensan;Escopyrinus;Espasnatex;Eufibran;Euprogan;Febren;Febrosolvin;Fenodone;Fever;Flivalgin;Flumil;Framidone;Ftalazon;Funapon;Galenopyrin;Glucopirina;Glucopitina;Helvagit-f;Hemicraneal;Hisense-p;Influnal depot;Inst;Irgapyrine;Isoftal;Kalmine;Katareuma;Lagaflex;Latepyrine;Lauroanginol;Manslu;Medispanmin;Meloka;Neuro-demoplast;Nifedon;Nikartrone;Nostress;Optineural(analgesic);Optipax;Osadrine;Osmotipax;P.s.b.p.;Piracodid;Piradenil;Piradol;Pirasco;Piraseptolo.

World Health Organization (WHO)

Aminophenazone, a pyrazolone derivative, has been used as an antiinflammatory and analgesic agent for over a century. Its use has been associated with cases of bone marrow depression and agranulocytosis and more recently it has been claimed to have a carcinogenic potential. Products containing aminophenazone have been formally withdrawn in many countries and marketing has been voluntarily suspended in others. Elsewhere, however, proprietary preparations containing this ingredient may remain available. (Reference: (WHODI) WHO Drug Information, 3, 9, 1977)

General Description

Small colorless crystals or white crystalline powder. Aqueous solution slightly alkaline to litmus. pH (5% water solution) 7.5-9. Odorless. Slightly bitter taste.

Air & Water Reactions

Water soluble.

Reactivity Profile

Aminophenazone is sensitive to exposure to light. Aminophenazone is readily attacked by mild oxidizing agents in the presence of water. Aminophenazone is incompatible with acacia, apomorphine, aspirin, chloral hydrate, iodine and tannic acid.

Fire Hazard

Flash point data for Aminophenazone are not available; however, Aminophenazone is probably combustible.

Safety Profile

Human poison by unspecified route. Experimental poison by ingestion, subcutaneous, intramuscular,intravenous, and intraperitoneal routes. Moderately toxic by parenteral route. Experimental teratogenic and reproductive effects. Questionable carcinogen when mixed with NaNO2 (1:l). Mutation data reported. Can cause bone marrow depression resulting in leucopenia. Has been implicated in development of aplastic anemia. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

It crystallises from pet ether, sublimes between 80o and 90o, and forms metal complexes. [Beilstein 25 H 452, 25 III/IV 3555.]

4-DiMethylaMino Antipyrine Preparation Products And Raw materials

Raw materials

Preparation Products


4-DiMethylaMino Antipyrine Suppliers

Global( 257)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20911 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29955 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5912 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Standardpharm Co. Ltd.
86-714-3992388
overseasales1@yongstandards.com United States 14344 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47498 58

View Lastest Price from 4-DiMethylaMino Antipyrine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-03 4-DiMethylaMino Antipyrine
58-15-1
US $44.00 / KG 1KG 99% 1000kg/month Shanxi Lianxu New Material Co., LTD
2021-12-03 4-DiMethylaMino Antipyrine
58-15-1
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-11-16 AMinophenazone
58-15-1
US $0.00 / KG 1g 99% 50kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

4-DiMethylaMino Antipyrine Spectrum


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