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Ryanodine

Ryanodine
Ryanodine structure
CAS No.
15662-33-6
Chemical Name:
Ryanodine
Synonyms
Ryanex;ryania;RYANADOL;ryanexel;Ryanexcel;Ryanicide;RYANODINE;bonideryatox;ryaniapowder;Ryanodine,99%
CBNumber:
CB1480087
Molecular Formula:
C25H35NO9
Formula Weight:
493.55
MOL File:
15662-33-6.mol

Ryanodine Properties

alpha 
D25 +26° (methanol)
Boiling point:
586.95°C (rough estimate)
Density 
1.2805 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
White solid
Melting point:
219-220 °C
pka
10.66±0.70(Predicted)
color 
white to beige
CAS DataBase Reference
15662-33-6
FDA UNII
37H6ATE4SA
EPA Substance Registry System
Ryanodine (15662-33-6)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302+H312-H410
Precautionary statements  P273-P280-P501
Hazard Codes  Xn,N
Risk Statements  21/22-50/53
Safety Statements  36/37-60-61
RIDADR  UN 3077 9/PG 3
RTECS  VM4025000

Ryanodine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 559276 Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. 15662-33-6 500 μg $205.35 2021-03-22 Buy
Sigma-Aldrich 559276 Ryanodine, High Purity 15662-33-6 500ug $214 2020-08-18 Buy

Ryanodine Chemical Properties,Uses,Production

Description

Ryania insecticide is the ground stem wood of the tropical tree Ryania speciosa Vahl., and it contains over a dozen of several structurally related alkaloids. Nowadays, this botanical preparation is of minor importance, but one of its major ingredients, ryanodine, is a widely used pharmacological tool in studies of the calcium release channels in sarcoplasmic reticulum membranes of skeletal and cardiac muscle of both insects and mammals (11,12).

Chemical Properties

white to off-white solid

Uses

Insecticide.

Definition

ChEBI: An insecticide alkaloid isolated from South American plant Ryania speciosa.

Biological Activity

Potent inhibitor of Ca 2+ release from sarcoplasmic reticulum (IC 50 values are 10 and 2.8 nM in skeletal and cardiac muscle respectively).

References

Rogers et ai., J. Amer. Chem. Soc., 70, 3086 (1948)
Kelly, Whittingham, Wusner., Chem. Ind., 857 (1952)
Structure:
Wiesner, Valenta, Findlay., Tetrahedron Lett., 221 (1967)
Hollstein, Rapoport.,J. Amer. Chem. Soc., 90,3864 (1968)
Wong, Hollstein, Rapoport., ibid, 90, 3866 (1968)
Wiesner., Collect. Czech. Chem. Commun., 33, 2656 (1968)
Crystal structure:
Srivastava, Przybylska., Can. J. Chem., 46,795 (1968)

Ryanodine Preparation Products And Raw materials

Raw materials

Preparation Products


Ryanodine Suppliers

Global( 96)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 821-50328103-801
86-21-50328109 3bsc@sina.com China 15877 69
Ascent Scientific 4401179829988
4402030 700 369 customerservice@ascentscientific.co.uk United Kingdom 279 60
Sichuan Wei Keqi Biological Technology Co., Ltd. 18116577057 028-81700200-
028-81705658 2851167785@qq.com China 4701 56
Biyu Biotechnology (Shanghai) Co., ltd 021-26018599
support@biyubiotech.com China 270 56
Shenzhen Regent Biochemical Technology Co., Ltd. 18938635012 0755-85201366-
0755-85201366 sales@regentsciences.com China 9512 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 400-002-6226
sales@biochemall.cn China 54467 58
Absin Bioscience Inc. 15502157206
info@absin.cn China 23932 58
Energy Chemical 400-005-6266 021-58432009-
021-58436166 marketing1@energy-chemical.com China 45013 58

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